ID A0A1U7I340_9CYAN Unreviewed; 937 AA.
AC A0A1U7I340;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=TIR domain-containing protein {ECO:0000259|PROSITE:PS50104};
GN ORFNames=NIES2119_30845 {ECO:0000313|EMBL:OKH30477.1};
OS Phormidium ambiguum IAM M-71.
OC Bacteria; Cyanobacteriota; Cyanophyceae; Oscillatoriophycideae;
OC Oscillatoriales; Oscillatoriaceae; Phormidium.
OX NCBI_TaxID=454136 {ECO:0000313|EMBL:OKH30477.1, ECO:0000313|Proteomes:UP000185860};
RN [1] {ECO:0000313|EMBL:OKH30477.1, ECO:0000313|Proteomes:UP000185860}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=IAM M-71 {ECO:0000313|EMBL:OKH30477.1,
RC ECO:0000313|Proteomes:UP000185860};
RA Zhu T., Hou S., Lu X., Hess W.R.;
RT "Draft Genome Sequences of Nine Cyanobacterial Strains from Diverse
RT Habitats.";
RL Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton
CC {ECO:0000256|ARBA:ARBA00004245}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OKH30477.1}.
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DR EMBL; MRCE01000064; OKH30477.1; -; Genomic_DNA.
DR RefSeq; WP_073597318.1; NZ_MRCE01000064.1.
DR AlphaFoldDB; A0A1U7I340; -.
DR STRING; 454136.NIES2119_30845; -.
DR OrthoDB; 434800at2; -.
DR Proteomes; UP000185860; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd00200; WD40; 2.
DR Gene3D; 3.40.50.10140; Toll/interleukin-1 receptor homology (TIR) domain; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 5.
DR InterPro; IPR020472; G-protein_beta_WD-40_rep.
DR InterPro; IPR011044; Quino_amine_DH_bsu.
DR InterPro; IPR000157; TIR_dom.
DR InterPro; IPR035897; Toll_tir_struct_dom_sf.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR019775; WD40_repeat_CS.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR44129:SF1; PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE IB SUBUNIT BETA; 1.
DR PANTHER; PTHR44129; WD REPEAT-CONTAINING PROTEIN POP1; 1.
DR Pfam; PF13676; TIR_2; 1.
DR Pfam; PF00400; WD40; 14.
DR PRINTS; PR00320; GPROTEINBRPT.
DR SMART; SM00255; TIR; 1.
DR SMART; SM00320; WD40; 14.
DR SUPFAM; SSF52200; Toll/Interleukin receptor TIR domain; 1.
DR SUPFAM; SSF50978; WD40 repeat-like; 2.
DR SUPFAM; SSF50969; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR PROSITE; PS50104; TIR; 1.
DR PROSITE; PS00678; WD_REPEATS_1; 4.
DR PROSITE; PS50082; WD_REPEATS_2; 14.
DR PROSITE; PS50294; WD_REPEATS_REGION; 13.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000185860};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius};
KW WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW ProRule:PRU00221}.
FT TRANSMEM 203..224
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 1..128
FT /note="TIR"
FT /evidence="ECO:0000259|PROSITE:PS50104"
FT REPEAT 302..333
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 343..375
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 384..415
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 424..465
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 469..510
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 513..547
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 554..588
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 595..627
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 636..668
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 677..718
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 722..756
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 763..797
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 839..861
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 861..902
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
SQ SEQUENCE 937 AA; 104898 MW; 3935840A145E9D89 CRC64;
MTDIFISYSR KDKDFVKELH LRLIKLRRDV WVDWEDIPLT ADWKEEIYRG IEGTDNFLFI
LSPDSIKSLY CTEELEYAIK NHKRLIPVVY REVNPQDVHP TLAALNWIFI RNEDDFHSNF
EKLLEAIDTD LDYVRIHTRL LKRAIEWHSE KYDSSFLLRG KDLKTALEWL TDSQEQQPSP
TFLHKQYIIR SNEAESKRQK RTVTAISFGM SITTILTILS FGLYQRAEEL RLQAEKENLF
ALSKTSEALF VSEQKFDALV EAIRAGVKLK QSTWAIKEKP VQNLILTELQ QAILWVIESN
QIEGHIDSVQ AVAWSPDGEL IATASEDRTA KIWHRNGSLI ATLEGHKGTI WAVDWSQDSQ
LIATASDDKT VKIWNRQGQL LTTLTGHTAP VYAVVFSRNN IIATGGQDQT VKLWNSEGKL
LRTLQGQNSE VWWLTWTADG KKLATAGNDK LVRIWDLSNP KSLKPVFTLA GHTKEVNAVS
FSPDGQILAS ASADKTVKLW NVSRKKPILL HTLSGHTEQV YAISFAPNGK TVATGSFDNT
AKIWKIDGTL VKTLKGHKSE VYGVAWSPDS KMLITSSFDS SVKIWHLDKT VPKVISGHED
AVSAISFSSD GKNIVSASWD KTVKIWQPDG KLINTIKGHT GFVRRASFSP NGKMIATTSS
DNLVKLWNQQ GKELNTLIGH ESLINSLAWS HDGKLIASAS NDKAVKIWDV SGNKPLLLHT
ITAAHKAAVL DVAFSPDGKS LVTASADKLI KHWTVKGKLL ATFVGHTDVV NSVSFSPDGQ
LIVSSSDDKT VKVWQIQGKL LRTMRGHSDR VWEAIFSPQE KLILPVAKTN KTTEKHLIIA
SASIDRTVKL WELDGTELVS LKGHKDGVIS LSFSPDGKIL ASGGLDNNII LWNLQQVGTL
DKLLVKGCRW IEDYLKSNPN VEKSDRQLCK SVFTSQS
//
