ID A0A1U7LGB7_NEOID Unreviewed; 1024 AA.
AC A0A1U7LGB7;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE RecName: Full=Exportin-T {ECO:0000256|ARBA:ARBA00018928, ECO:0000256|RuleBase:RU366037};
DE AltName: Full=Exportin(tRNA) {ECO:0000256|RuleBase:RU366037};
DE AltName: Full=tRNA exportin {ECO:0000256|RuleBase:RU366037};
GN ORFNames=NEOLI_004020 {ECO:0000313|EMBL:OLL21700.1};
OS Neolecta irregularis (strain DAH-3).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Neolectales;
OC Neolectaceae; Neolecta.
OX NCBI_TaxID=1198029 {ECO:0000313|EMBL:OLL21700.1, ECO:0000313|Proteomes:UP000186594};
RN [1] {ECO:0000313|EMBL:OLL21700.1, ECO:0000313|Proteomes:UP000186594}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DAH-3 {ECO:0000313|EMBL:OLL21700.1,
RC ECO:0000313|Proteomes:UP000186594};
RA Cisse O., Nguyen A., Hewitt D.A., Jedd G., Stajich J.E.;
RT "Evolutionary innovation and constraint leading to complex multicellularity
RT in the Ascomycota.";
RL Submitted (APR-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: tRNA nucleus export receptor which facilitates tRNA
CC translocation across the nuclear pore complex.
CC {ECO:0000256|RuleBase:RU366037}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496,
CC ECO:0000256|RuleBase:RU366037}. Nucleus
CC {ECO:0000256|RuleBase:RU366037}. Note=Shuttles between the nucleus and
CC the cytoplasm. {ECO:0000256|RuleBase:RU366037}.
CC -!- SIMILARITY: Belongs to the exportin family.
CC {ECO:0000256|ARBA:ARBA00009466, ECO:0000256|RuleBase:RU366037}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OLL21700.1}.
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DR EMBL; LXFE01004390; OLL21700.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1U7LGB7; -.
DR STRING; 1198029.A0A1U7LGB7; -.
DR OMA; HEMFLFG; -.
DR OrthoDB; 2546268at2759; -.
DR Proteomes; UP000186594; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0031267; F:small GTPase binding; IEA:InterPro.
DR GO; GO:0000049; F:tRNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0071528; P:tRNA re-export from nucleus; IEA:UniProtKB-UniRule.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 2.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR013598; Exportin-1/Importin-b-like.
DR InterPro; IPR045546; Exportin-T_C.
DR InterPro; IPR040017; XPOT.
DR PANTHER; PTHR15952:SF11; EXPORTIN-T; 1.
DR PANTHER; PTHR15952; EXPORTIN-T/LOS1; 1.
DR Pfam; PF19282; Exportin-T; 1.
DR Pfam; PF08389; Xpo1; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|RuleBase:RU366037};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|RuleBase:RU366037};
KW Reference proteome {ECO:0000313|Proteomes:UP000186594};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|RuleBase:RU366037};
KW Transport {ECO:0000256|RuleBase:RU366037};
KW tRNA-binding {ECO:0000256|ARBA:ARBA00022555,
KW ECO:0000256|RuleBase:RU366037}.
FT DOMAIN 160..309
FT /note="Exportin-1/Importin-beta-like"
FT /evidence="ECO:0000259|Pfam:PF08389"
FT DOMAIN 374..1021
FT /note="Exportin-T C-terminal"
FT /evidence="ECO:0000259|Pfam:PF19282"
FT REGION 72..125
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 76..125
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1024 AA; 114332 MW; 259BF87A4CFEE7B4 CRC64;
MDAQIEQAVA CALDAAGDAD VKAQAIAFCE QLKRSADGLR VCLALFMHRP RRSDAARLFA
LQVVEAALQA DGEMRDGGHT SGHIDDRIHP DGDRLDDRID SDRIDSEHTS EHTDSDHGNR
IHPDDRDLNH ALSPIDIART ALYRWLCAEI AAAGPDMVGP PFLRNRLAHT LTLLYVHSHP
AAWPSFFSDL LALLRPPAPR PLVTEFVLRV LADIHLEIAD VAVHRSPRAL SKNHRLKDTI
RARDIHTVIP FCLHVAVEYT PTHPRIAAAS LDVLAKWAAW TDLALILNSP FVAHISSFLA
HKDIQIATSA ALTEIVRKKM KPQDKLALIQ TLNLNTVFGQ LDLVPDLEFG ESLGSLINAQ
GQELVRVLHD SSASALARSL FLEMFPHILR CLASEYDDIS ETVLFVLTDF LTSLRKDAKS
GCAHSDELAT LPLLLEISMR KSRYDSESNW GPDADSDEDA LFQELRRKLR NFEEIICAID
PALFEQATLS LVLEPLKSFS KHSNWRDLEL ILHLMFDFGE TMPGNPTYVS DQGPTALGKM
MTHLIESDIL SFPHPAVQLQ YLEVVVRYHG FFKLYPNAIP SLLASLVGGQ GVHHPETRVR
TRAWYLFHRF VKSLRAKIGI VAEDVLYAMQ DMLVIKANDI SRQAIHVDAG IITLDVGPFD
SLLYLFETAG ILVSVDAISP SKRAILTQAV VGPLILDMKA ADTTSPVAIV QLHHSFMSLG
NFAKGFPENK NKDGIESIFE ESAEALLSAL QVHKQHRIIR EAARFTFSRL CGVLDLTILS
KTPRLLNALV ENAGVEELSD VLPYLGQLVF RFTTEVCDML NAVIMPLFQR VLEALQVAPE
GTDDSIGLVQ LQKAYLTFII MIFSNDVDKI FYSPENISFL ETLLQSIIHY ASDSADASTK
RLAFSVLAKM VSKWSSGSDS QPVQGFDEFV FKYVSRMCFQ VATTPSFNLR DGQGILLLNE
IASLQKTIFE KNKDVYVQYL GNIYFPSMNL TGSLSLDYIQ ALVRLDLKDF RKFFKGWIQQ
LRYT
//
