ID   A0A1U7LHW9_NEOID        Unreviewed;       347 AA.
AC   A0A1U7LHW9;
DT   10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT   10-MAY-2017, sequence version 1.
DT   27-MAR-2024, entry version 17.
DE   SubName: Full=2-alkenal reductase (NADP(+)-dependent) {ECO:0000313|EMBL:OLL22247.1};
GN   ORFNames=NEOLI_004823 {ECO:0000313|EMBL:OLL22247.1};
OS   Neolecta irregularis (strain DAH-3).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Neolectales;
OC   Neolectaceae; Neolecta.
OX   NCBI_TaxID=1198029 {ECO:0000313|EMBL:OLL22247.1, ECO:0000313|Proteomes:UP000186594};
RN   [1] {ECO:0000313|EMBL:OLL22247.1, ECO:0000313|Proteomes:UP000186594}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DAH-3 {ECO:0000313|EMBL:OLL22247.1,
RC   ECO:0000313|Proteomes:UP000186594};
RA   Cisse O., Nguyen A., Hewitt D.A., Jedd G., Stajich J.E.;
RT   "Evolutionary innovation and constraint leading to complex multicellularity
RT   in the Ascomycota.";
RL   Submitted (APR-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OLL22247.1}.
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DR   EMBL; LXFE01003628; OLL22247.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1U7LHW9; -.
DR   STRING; 1198029.A0A1U7LHW9; -.
DR   OMA; PIKNIHN; -.
DR   OrthoDB; 179761at2759; -.
DR   Proteomes; UP000186594; Unassembled WGS sequence.
DR   GO; GO:0016628; F:oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR   CDD; cd05288; PGDH; 1.
DR   Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR013149; ADH-like_C.
DR   InterPro; IPR041694; ADH_N_2.
DR   InterPro; IPR011032; GroES-like_sf.
DR   InterPro; IPR045010; MDR_fam.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR020843; PKS_ER.
DR   PANTHER; PTHR43205; PROSTAGLANDIN REDUCTASE; 1.
DR   PANTHER; PTHR43205:SF7; PROSTAGLANDIN REDUCTASE 1; 1.
DR   Pfam; PF16884; ADH_N_2; 1.
DR   Pfam; PF00107; ADH_zinc_N; 1.
DR   SMART; SM00829; PKS_ER; 1.
DR   SUPFAM; SSF50129; GroES-like; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE   4: Predicted;
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW   Reference proteome {ECO:0000313|Proteomes:UP000186594}.
FT   DOMAIN          22..343
FT                   /note="Enoyl reductase (ER)"
FT                   /evidence="ECO:0000259|SMART:SM00829"
SQ   SEQUENCE   347 AA;  38318 MW;  464A904648954734 CRC64;
     MSQLSNNAVL FNNIPESMPV KGKDLVFVQQ SFDLNQILLN PGDFVLQTLY LSLDPFMRFR
     MRDPKVKSYV DAFELGKPVI NLGIGRVIKS ENSQYPIGVL LEGILPFQEY ITVVSNNSNC
     IRSVVKEIPG IPLSAYLGLL GVSCWTAFIG LYDIGRIKSG ETIFVSAASG AVGQLVVQLA
     KLEGLRVIAS AGSAEKVEFL KNELGCDEAF NYKQEQPRVA LKKYCPNGLD VFFDNVGGAT
     LEAALSMAND HARFIECGMI SQYNSSGLPG PRNLTLIVTK RIRMEGFIIS DHKHKFKEYT
     NKMIQLVLDR RIVFKEHVSY GIENAIDGLI GMLKGDKLGK ALVKLAD
//