ID A0A1U7LN09_NEOID Unreviewed; 1147 AA.
AC A0A1U7LN09;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 22-FEB-2023, entry version 21.
DE SubName: Full=Cell division control protein 45 {ECO:0000313|EMBL:OLL23973.1};
GN ORFNames=NEOLI_003419 {ECO:0000313|EMBL:OLL23973.1};
OS Neolecta irregularis (strain DAH-3).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Neolectales;
OC Neolectaceae; Neolecta.
OX NCBI_TaxID=1198029 {ECO:0000313|EMBL:OLL23973.1, ECO:0000313|Proteomes:UP000186594};
RN [1] {ECO:0000313|EMBL:OLL23973.1, ECO:0000313|Proteomes:UP000186594}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DAH-3 {ECO:0000313|EMBL:OLL23973.1,
RC ECO:0000313|Proteomes:UP000186594};
RA Cisse O., Nguyen A., Hewitt D.A., Jedd G., Stajich J.E.;
RT "Evolutionary innovation and constraint leading to complex multicellularity
RT in the Ascomycota.";
RL Submitted (APR-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the CDC45 family.
CC {ECO:0000256|ARBA:ARBA00010727}.
CC -!- SIMILARITY: Belongs to the major facilitator superfamily. Sugar
CC transporter (TC 2.A.1.1) family. {ECO:0000256|ARBA:ARBA00010992}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OLL23973.1}.
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DR EMBL; LXFE01001049; OLL23973.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1U7LN09; -.
DR STRING; 1198029.A0A1U7LN09; -.
DR OrthoDB; 1698487at2759; -.
DR Proteomes; UP000186594; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR GO; GO:0006270; P:DNA replication initiation; IEA:InterPro.
DR Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 1.
DR InterPro; IPR003874; CDC45.
DR InterPro; IPR020846; MFS_dom.
DR InterPro; IPR005828; MFS_sugar_transport-like.
DR InterPro; IPR036259; MFS_trans_sf.
DR PANTHER; PTHR10507; CDC45-RELATED PROTEIN; 1.
DR PANTHER; PTHR10507:SF0; CELL DIVISION CONTROL PROTEIN 45 HOMOLOG; 1.
DR Pfam; PF02724; CDC45; 1.
DR Pfam; PF00083; Sugar_tr; 2.
DR SUPFAM; SSF103473; MFS general substrate transporter; 1.
DR PROSITE; PS50850; MFS; 1.
PE 3: Inferred from homology;
KW Cell cycle {ECO:0000256|ARBA:ARBA00023306};
KW Cell division {ECO:0000313|EMBL:OLL23973.1};
KW DNA replication {ECO:0000256|ARBA:ARBA00022705};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000186594};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 91..110
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 117..139
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 194..216
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 222..242
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 273..293
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 313..332
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 339..360
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 366..383
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 404..423
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 443..461
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 49..465
FT /note="Major facilitator superfamily (MFS) profile"
FT /evidence="ECO:0000259|PROSITE:PS50850"
FT REGION 667..720
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 673..718
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1147 AA; 128397 MW; 13E317D361ED0F35 CRC64;
MTALPIHDKG TVSGPLISQI STDSIPTDVF SSDKGDPEVP KSALERLINI FACGSVLFSD
GYLNGVIGPV NTILKTIYPQ EYQNSNYSKK VSSIVFAGTV VGQLLFGYLS DKQGRRFGML
SATIILIVFS VLSAGSMGLK HSIHGMLDAL TAWRFFLGIG IGAEYPAGSV ACSEASSEQE
EGSRHAWFVM FTNFQIDLGF VLSSLIPFIL ICIFSQDHLH IIWRLALGFG ALPPLSVFYF
RLTMKEPAAY KKGNMKNTRI PYGLVVKKYW KRLVPIATVW FLYDFSAYSF SIYSTSILQK
IVPDGSLRKN FGWNTLIMTF YLPGAMCGGF AADRFGPRMV LFVGLMLQAL VGFLMSGLYS
HLMNNIGAFC VVYGLFLTFG EFGPGDNIGL IAAKSSPTAI RGQFYGIAAA VGKVGAFVGS
FVFPDIIKRF GGPETIRGNS GPFYIGSALA VVSGLIGLFF LPNVSQQSLE EEDAEFSRYL
QENNFDITTM GLQCRLDVEQ AAIVERDGRL TALYIWRLMG YITRNNYAKA YQKLRPLSFQ
GSCSVLLFVA LDVDALCACK MLARMMKRDY IPHKIHPVAG YQDLEKANRE LVQDDEELKF
IFMINCGALI DLVGYLQPRQ GLTIYVIDSH RPWNLDNLFV EGEVVVWDDG EIEMDMKEEK
EAYIELSEMP EVSSDDEENK VVQDTTRKRK SRSRSDEEES DSSINSRPRQ RRKTSSASET
ADSFKYVENP YLALRRKRGK HQSTISTYYD RGTWYGESVS GVIYSLASEL SLEDNDLLWL
AIIGLTNQDL SRRGKYSHYY PLLKDEVNRL NPPPLSGERR INGRNPSDKS IKAECEFRFM
MVRHWSLYDS MLHSPYLSAK LHLWSENGRK KLHKLLAKIG FSLVQCRQIY SHMDMDLKRT
LRDKLGGMAG MYGLDQIIFE SFTRCWGFKV TLSASDAAYA LGAILEMGVP EKENTVSLSE
SKELGEEWSK NFYTAMDSLD DIDRLRRGLS TAMDLQKAIV RTGTVLLEKR LIRQLSAFRM
AIVKDGPDLA IFTHPQALGK LALWISEAIA EQEKEQFRRH PLPFVIASLD ESTDGYLIVG
TSVSSSSSHE SVPKHPGLNR FGLAFQEVAR TSGARVRIDS FEASVVECRK DDFVGFLEGL
SLRAALD
//
