ID A0A1U7LNR2_NEOID Unreviewed; 1032 AA.
AC A0A1U7LNR2;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=GTPase-activating protein {ECO:0000313|EMBL:OLL24295.1};
GN ORFNames=NEOLI_003595 {ECO:0000313|EMBL:OLL24295.1};
OS Neolecta irregularis (strain DAH-3).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Neolectales;
OC Neolectaceae; Neolecta.
OX NCBI_TaxID=1198029 {ECO:0000313|EMBL:OLL24295.1, ECO:0000313|Proteomes:UP000186594};
RN [1] {ECO:0000313|EMBL:OLL24295.1, ECO:0000313|Proteomes:UP000186594}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DAH-3 {ECO:0000313|EMBL:OLL24295.1,
RC ECO:0000313|Proteomes:UP000186594};
RA Cisse O., Nguyen A., Hewitt D.A., Jedd G., Stajich J.E.;
RT "Evolutionary innovation and constraint leading to complex multicellularity
RT in the Ascomycota.";
RL Submitted (APR-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OLL24295.1}.
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DR EMBL; LXFE01000886; OLL24295.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1U7LNR2; -.
DR STRING; 1198029.A0A1U7LNR2; -.
DR OMA; EAYMITL; -.
DR OrthoDB; 24454at2759; -.
DR Proteomes; UP000186594; Unassembled WGS sequence.
DR GO; GO:0005938; C:cell cortex; IEA:UniProt.
DR GO; GO:0032153; C:cell division site; IEA:UniProt.
DR GO; GO:0000776; C:kinetochore; IEA:InterPro.
DR GO; GO:0005096; F:GTPase activator activity; IEA:UniProt.
DR GO; GO:0000070; P:mitotic sister chromatid segregation; IEA:InterPro.
DR CDD; cd05132; RasGAP_GAPA; 1.
DR InterPro; IPR013950; Mis14/Nsl1.
DR InterPro; IPR000593; RasGAP_C.
DR InterPro; IPR023152; RasGAP_CS.
DR InterPro; IPR001936; RasGAP_dom.
DR InterPro; IPR008936; Rho_GTPase_activation_prot.
DR PANTHER; PTHR14149:SF17; GTPASE-ACTIVATING PROTEIN; 1.
DR PANTHER; PTHR14149; RAS GTPASE-ACTIVATING PROTEIN WITH IQ MOTIF; 1.
DR Pfam; PF08641; Mis14; 1.
DR Pfam; PF00616; RasGAP; 1.
DR Pfam; PF03836; RasGAP_C; 1.
DR SMART; SM00323; RasGAP; 1.
DR SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR SUPFAM; SSF143885; RGC domain-like; 1.
DR PROSITE; PS00509; RAS_GTPASE_ACTIV_1; 1.
DR PROSITE; PS50018; RAS_GTPASE_ACTIV_2; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000186594}.
FT DOMAIN 182..398
FT /note="Ras-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50018"
FT REGION 1..37
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 55..82
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 17..37
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1032 AA; 116331 MW; B0D2807E376C98C7 CRC64;
MSLLSANGPP PSPGISRLAS RRTTTFSSHS DSSRSARSSK RYSVTAIYSI AAEQDVEVQD
ELSRAQRKLR ELKAKISVQS KKNFVLERDV RYLDSRIALL IQNRMALDEQ NEVASHLEGA
EELLVGTFPD DRKLNLYSNL FFLLQTEPRH IASLCRLVTL TEIDTLLQTV MFTIYGQQYE
SREEHLLLTM FQSVLSAQFE ATTEFASLLR QNTPVSRMMN TYTRRGPGQA YLRTVLAERI
NSLIEHKDLN LEINPLKVYE QMLNQIEQES GKLPGHLPRG VSAEVAALND DTVAIIRPRL
TMLMEVANSF LNTIIGSIDA VPYGIRWICK QIRSLTRRKY PEGSELAVCS LIGGFFFLRF
INPAIVTPHA YMLVDGVPRD SPRRTLTLVA KMLQNLANKP SYAKEPYMTN LSPFIDSNKA
RINKFLNDLC EVGDFYESLE IDQYIALSKK DLRLNITLNE VYSTHALLEK HLGVISPDSN
SHLRIILNEL GHAPAPLPRK ENRAIEVELY SRWESPVSEL TEALDITSSD LLFMETKSAF
VQLIRSLPPS SSALKYPLDL QKVADTAAKL KDAGLVRKGI KALDMLRELA ELHVVDKNDR
FNPLVDEVDQ ELAHLGSLRE KVIRETRSLD SVYKTICDHN EYLRSQLETY KSYLQNVRSG
GVSGGVGLVT VGGKEKKAPK SQLLGPYKFT FQQLEKEGII VASSIPEQRR SHTFFDLSSP
VPGTFIIALK YKGRSKGLLE LDLKLDDLLE MQQNNMNKLD LEYVHLDVGV GSVLVDISAI
IDLNLTPRIP FTFCDVFFFL MFEVGLVVYS KFGHPAMTGQ DPQTLPKIEL ESLKDLLFLS
DNLSRAAHEK LEQNLPSTNE DDPVRQAVDK ALQQFLTRTF ELALPSIRVN GMNADVVQFR
EATKESTEVF EPYNPDLIHQ VEDLQKEIED TTLSISQLRR NAPKKIAQIY ASSLEPDVAQ
TLPVDENDPM EEAISVPFIP REESVRSEYI HLMENLQKLT KTIPSAVAHV ERAHDVVRTL
SGAAKSRIPP HS
//
