ID A0A1U7LPB5_NEOID Unreviewed; 515 AA.
AC A0A1U7LPB5;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Putative hydroxymethylpyrimidine/phosphomethylpyrimidine kinase 2 isoform A {ECO:0000313|EMBL:OLL24495.1};
DE SubName: Full=Putative hydroxymethylpyrimidine/phosphomethylpyrimidine kinase 2 isoform B {ECO:0000313|EMBL:OLL24496.1};
GN ORFNames=NEOLI_004528 {ECO:0000313|EMBL:OLL24495.1};
OS Neolecta irregularis (strain DAH-3).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Neolectales;
OC Neolectaceae; Neolecta.
OX NCBI_TaxID=1198029 {ECO:0000313|EMBL:OLL24495.1, ECO:0000313|Proteomes:UP000186594};
RN [1] {ECO:0000313|EMBL:OLL24495.1, ECO:0000313|Proteomes:UP000186594}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DAH-3 {ECO:0000313|EMBL:OLL24495.1,
RC ECO:0000313|Proteomes:UP000186594};
RA Cisse O., Nguyen A., Hewitt D.A., Jedd G., Stajich J.E.;
RT "Evolutionary innovation and constraint leading to complex multicellularity
RT in the Ascomycota.";
RL Submitted (APR-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OLL24495.1}.
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DR EMBL; LXFE01000766; OLL24495.1; -; Genomic_DNA.
DR EMBL; LXFE01000766; OLL24496.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1U7LPB5; -.
DR STRING; 1198029.A0A1U7LPB5; -.
DR OMA; FWEMFPY; -.
DR OrthoDB; 5477821at2759; -.
DR Proteomes; UP000186594; Unassembled WGS sequence.
DR GO; GO:0008972; F:phosphomethylpyrimidine kinase activity; IEA:InterPro.
DR GO; GO:0050334; F:thiaminase activity; IEA:InterPro.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR GO; GO:0009228; P:thiamine biosynthetic process; IEA:InterPro.
DR CDD; cd01169; HMPP_kinase; 1.
DR CDD; cd19367; TenA_C_ScTHI20-like; 1.
DR Gene3D; 3.40.1190.20; -; 1.
DR Gene3D; 1.20.910.10; Heme oxygenase-like; 1.
DR InterPro; IPR016084; Haem_Oase-like_multi-hlx.
DR InterPro; IPR004399; HMP/HMP-P_kinase_dom.
DR InterPro; IPR013749; PM/HMP-P_kinase-1.
DR InterPro; IPR029056; Ribokinase-like.
DR InterPro; IPR004305; Thiaminase-2/PQQC.
DR InterPro; IPR027574; Thiaminase_II.
DR NCBIfam; TIGR00097; HMP-P_kinase; 1.
DR NCBIfam; TIGR04306; salvage_TenA; 1.
DR PANTHER; PTHR20858:SF17; HYDROXYMETHYLPYRIMIDINE_PHOSPHOMETHYLPYRIMIDINE KINASE THI20-RELATED; 1.
DR PANTHER; PTHR20858; PHOSPHOMETHYLPYRIMIDINE KINASE; 1.
DR Pfam; PF08543; Phos_pyr_kin; 1.
DR Pfam; PF03070; TENA_THI-4; 1.
DR SUPFAM; SSF48613; Heme oxygenase-like; 1.
DR SUPFAM; SSF53613; Ribokinase-like; 1.
PE 4: Predicted;
KW Kinase {ECO:0000313|EMBL:OLL24495.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000186594};
KW Transferase {ECO:0000313|EMBL:OLL24495.1}.
FT DOMAIN 17..277
FT /note="Pyridoxamine kinase/Phosphomethylpyrimidine kinase"
FT /evidence="ECO:0000259|Pfam:PF08543"
FT DOMAIN 299..508
FT /note="Thiaminase-2/PQQC"
FT /evidence="ECO:0000259|Pfam:PF03070"
SQ SEQUENCE 515 AA; 57091 MW; B0EE96A1F979CA28 CRC64;
METSKYLSRV LVIAGSDSSG GAGIQADLKV LTAHGVYGMT AITALTSQNT QEVNGIEVMD
SQFVRKQIDT CIEDIGIDVL KTGMLASPEI VAEVAAAIDR HKLINTVVDP VMVSTSGSVL
LSPSAVETYA KLLLPRTLIL TPNRDEARLL LCQTNSNCSD SKDDAMSLAR DIKALGPSYV
LVKGGQCPYM ENLTDANTIK KKFVIDILYD GSRFWEFKSE FVDSTSTHGT GCSLAAAIAS
NLALSQPVIQ AVENAIHYVQ AALSEAVSLG KGHGPINHTV SIYRLPFYKG KFYDYLIRHP
KICNIWTEYV DHSFVRQLAE GTLDKKAFMY YLVQDYMWLR HYARAHSLAG YKASTLSQSA
SSAAIVLYIE REIVLHKSFF DDFGISENDI NTTPESVESM AYSRYLLDLG LQGDWMGLQV
GLSPCLLGYG VIAKRLLTDS KIKRENNPYH RWIENYAGQD YERAVRLGQE LLEEHALKQS
TSRIAELVDI FAHATRLEAA FWQMGLDYVT KLMNT
//
