ID   A0A1U7LQR0_NEOID        Unreviewed;       491 AA.
AC   A0A1U7LQR0;
DT   10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT   10-MAY-2017, sequence version 1.
DT   27-MAR-2024, entry version 18.
DE   SubName: Full=Hormone-sensitive lipase {ECO:0000313|EMBL:OLL25010.1};
GN   ORFNames=NEOLI_000116 {ECO:0000313|EMBL:OLL25010.1};
OS   Neolecta irregularis (strain DAH-3).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Neolectales;
OC   Neolectaceae; Neolecta.
OX   NCBI_TaxID=1198029 {ECO:0000313|EMBL:OLL25010.1, ECO:0000313|Proteomes:UP000186594};
RN   [1] {ECO:0000313|EMBL:OLL25010.1, ECO:0000313|Proteomes:UP000186594}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DAH-3 {ECO:0000313|EMBL:OLL25010.1,
RC   ECO:0000313|Proteomes:UP000186594};
RA   Cisse O., Nguyen A., Hewitt D.A., Jedd G., Stajich J.E.;
RT   "Evolutionary innovation and constraint leading to complex multicellularity
RT   in the Ascomycota.";
RL   Submitted (APR-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OLL25010.1}.
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DR   EMBL; LXFE01000515; OLL25010.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1U7LQR0; -.
DR   STRING; 1198029.A0A1U7LQR0; -.
DR   OMA; FPEGWRY; -.
DR   OrthoDB; 37251at2759; -.
DR   Proteomes; UP000186594; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0016787; F:hydrolase activity; IEA:InterPro.
DR   Gene3D; 3.40.50.1820; alpha/beta hydrolase; 2.
DR   InterPro; IPR029058; AB_hydrolase.
DR   InterPro; IPR013094; AB_hydrolase_3.
DR   InterPro; IPR033140; Lipase_GDXG_put_SER_AS.
DR   PANTHER; PTHR23025:SF3; HORMONE-SENSITIVE LIPASE; 1.
DR   PANTHER; PTHR23025; TRIACYLGLYCEROL LIPASE; 1.
DR   Pfam; PF07859; Abhydrolase_3; 2.
DR   SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
DR   PROSITE; PS01174; LIPASE_GDXG_SER; 1.
PE   4: Predicted;
KW   Lipid metabolism {ECO:0000256|ARBA:ARBA00023098};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136};
KW   Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW   Reference proteome {ECO:0000313|Proteomes:UP000186594}.
FT   DOMAIN          74..219
FT                   /note="Alpha/beta hydrolase fold-3"
FT                   /evidence="ECO:0000259|Pfam:PF07859"
FT   DOMAIN          276..357
FT                   /note="Alpha/beta hydrolase fold-3"
FT                   /evidence="ECO:0000259|Pfam:PF07859"
FT   ACT_SITE        156
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU10038"
SQ   SEQUENCE   491 AA;  55994 MW;  8B4E85E42883D69F CRC64;
     MLNLYQFTHR TAEQLRVSLA KVSSPYLKFF VGLSKPRLKI KRKIVIPRNS AEPSEVWIYF
     NGSEEELKFQ RKLVFFIHGG GFISTNPECY EEVTFAWASE LNVPVVAINY KKAPEYPFPY
     ALYECRDLYL EIVKTNGAII GFEHSQPLTI AFAGDSAGGN LATSLIILLL TEHLDIPIPA
     GLVLVYPALD LNLTCWMTNE NMCLLRQESV RDVSDAVIDS KLNYEKRKSV LQPYSDNYSP
     RKSLVKIFQT PPPKEAEKCF SPTPRMKNAR TKLAMTSRVS FFQDRILSPE MLRAMVLLYV
     GPQNRPNFET DYLLCPLRAP TEVLAKFPKT YLLCGEKDAM VDDTVLLAGR IREAKRAALN
     RRQNLQMTSL SSSENDWIEI VLLRGVSHGF FQMAFILPEA KKAISKCRGW LKEILDDQSF
     ISPSFEDDDE PVEMKSSNSL LFPMGPTLPI SAMIPQNKEG HDTWERFVMQ ESDLLNRRRE
     GVMRGLQFTE S
//