ID A0A1U7MFA2_9FIRM Unreviewed; 1023 AA.
AC A0A1U7MFA2;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 24-JAN-2024, entry version 23.
DE SubName: Full=Multidrug resistance protein MdtC {ECO:0000313|EMBL:OLS56116.1};
GN Name=mdtC_2 {ECO:0000313|EMBL:OLS56116.1};
GN ORFNames=SPSPH_25050 {ECO:0000313|EMBL:OLS56116.1};
OS Sporomusa sphaeroides DSM 2875.
OC Bacteria; Bacillota; Negativicutes; Selenomonadales; Sporomusaceae;
OC Sporomusa.
OX NCBI_TaxID=1337886 {ECO:0000313|EMBL:OLS56116.1, ECO:0000313|Proteomes:UP000186950};
RN [1] {ECO:0000313|EMBL:OLS56116.1, ECO:0000313|Proteomes:UP000186950}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 2875 {ECO:0000313|EMBL:OLS56116.1,
RC ECO:0000313|Proteomes:UP000186950};
RA Poehlein A., Daniel R.;
RT "Genome sequence of Sporomusa sphaeroides DSM 2875.";
RL Submitted (FEB-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OLS56116.1}.
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DR EMBL; LSLJ01000002; OLS56116.1; -; Genomic_DNA.
DR RefSeq; WP_075756190.1; NZ_LSLJ01000002.1.
DR AlphaFoldDB; A0A1U7MFA2; -.
DR STRING; 1337886.SPSPH_25050; -.
DR OrthoDB; 8270at2; -.
DR Proteomes; UP000186950; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 3.30.70.1430; Multidrug efflux transporter AcrB pore domain; 2.
DR Gene3D; 3.30.70.1440; Multidrug efflux transporter AcrB pore domain; 1.
DR Gene3D; 3.30.70.1320; Multidrug efflux transporter AcrB pore domain like; 1.
DR Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR InterPro; IPR027463; AcrB_DN_DC_subdom.
DR InterPro; IPR001036; Acrflvin-R.
DR PANTHER; PTHR32063; -; 1.
DR PANTHER; PTHR32063:SF0; SWARMING MOTILITY PROTEIN SWRC; 1.
DR Pfam; PF00873; ACR_tran; 1.
DR PRINTS; PR00702; ACRIFLAVINRP.
DR SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000186950};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..32
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 332..351
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 358..379
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 385..409
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 429..449
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 461..484
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 531..550
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 847..867
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 879..897
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 903..924
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 952..971
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 983..1006
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 1023 AA; 109276 MW; F4F2AF6E1C46BC18 CRC64;
MKLTEISIKR PVFATVIILA LVVIGMVSYM SLDVDQYPSV EIPVVAVQVL YPGAAPEQVE
SKITKEVEDA VGVVAGVDHI MSTVSEGVST TIIQFTMDTN ADSAAQSVRD KLGTLQAKLP
DEAKTPTVLR FDPDDTPIMS IALTGNLSQR ELTILAEDLL EKRLQAVNGV AAVELKGALE
REIQIHLDNN QMSAYGLTIP EVLNSLRNEN IDSPGGKITD GQRKTDLRAV GKINETSQFL
TVPVASRGGV QLYLKNIADV KDTTAEVETL TKVNGTPALG IDIMKQSGSN TVKTVAVVKK
ELETIKKELP SGVDLVVVRD NSKTIEESVE DVQFNLVVGG VLAVAIVFLF LGNWRSTIIS
GITIPVSVIA SFVVMKALGF SLNTMSLLAL SLAVGLLIDD AIVVIENIVR HLEMGKDKMT
AALEGTAEIG LAVMATTFTL VAVFLPVGMM SGIVGQFFKE FGITVAASVL VSLFVAFTLT
PMLSSKYLNH ASIKGTGKLS QAWLTWNGKF DELTAKYGEF LRQALGHRGK VLLAAAVLFV
GSLLLTPLLG TTFVPDADNG EFTVTATVDP GMSVAAVGDM ADAMSQIIGA IPEVEMTYSV
ANTREISIFS QLVPKSERSI SDNEIIAGLR QQLKDIPGAD ISVMKQSGLS GGKPVSLVIQ
GQSLDTLAMI AEQVQQAVAG IPGAVEVSSS YEPGNPDAQF IVNRDRAADL GISSASIADT
LQTMFNGKVV TQYKDGDDSH DVRVILDPEE RRSLGNVNKV YLSGTARDEA GQAVMVPVSQ
VTDTVYATSP AQIKRYDNQQ QITISANLSG ITLGEFNSAF EKKAAEIDMP EGYQFVATGQ
TESMNDVFSS MVLALGMAVL FIFFVLAAQF ESYLDPFSIM LALPLAIIGA IIGLLVMGSE
LSMMSLIGII MLMGLVTKNA ILLVDFAKQR REQGVERNQA LVEAAIQRMR PIIMTTAAMI
FGMLPLALGI GPGAEARAPM AHAIIGGLVT STILTLVVVP VVYTVFDDIQ QGKFSLKKVF
RKA
//
