ID A0A1U7ML96_9FIRM Unreviewed; 797 AA.
AC A0A1U7ML96;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 24-JAN-2024, entry version 21.
DE SubName: Full=ComEC family competence protein {ECO:0000313|EMBL:OLS58351.1};
GN ORFNames=SPSPH_18890 {ECO:0000313|EMBL:OLS58351.1};
OS Sporomusa sphaeroides DSM 2875.
OC Bacteria; Bacillota; Negativicutes; Selenomonadales; Sporomusaceae;
OC Sporomusa.
OX NCBI_TaxID=1337886 {ECO:0000313|EMBL:OLS58351.1, ECO:0000313|Proteomes:UP000186950};
RN [1] {ECO:0000313|EMBL:OLS58351.1, ECO:0000313|Proteomes:UP000186950}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 2875 {ECO:0000313|EMBL:OLS58351.1,
RC ECO:0000313|Proteomes:UP000186950};
RA Poehlein A., Daniel R.;
RT "Genome sequence of Sporomusa sphaeroides DSM 2875.";
RL Submitted (FEB-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OLS58351.1}.
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DR EMBL; LSLJ01000001; OLS58351.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1U7ML96; -.
DR STRING; 1337886.SPSPH_18890; -.
DR Proteomes; UP000186950; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0030420; P:establishment of competence for transformation; IEA:InterPro.
DR CDD; cd07731; ComA-like_MBL-fold; 1.
DR Gene3D; 3.60.15.10; Ribonuclease Z/Hydroxyacylglutathione hydrolase-like; 1.
DR InterPro; IPR035681; ComA-like_MBL.
DR InterPro; IPR004477; ComEC_N.
DR InterPro; IPR004797; Competence_ComEC/Rec2.
DR InterPro; IPR025405; DUF4131.
DR InterPro; IPR001279; Metallo-B-lactamas.
DR InterPro; IPR036866; RibonucZ/Hydroxyglut_hydro.
DR NCBIfam; TIGR00360; ComEC_N-term; 1.
DR NCBIfam; TIGR00361; ComEC_Rec2; 1.
DR PANTHER; PTHR30619; DNA INTERNALIZATION/COMPETENCE PROTEIN COMEC/REC2; 1.
DR PANTHER; PTHR30619:SF1; RECOMBINATION PROTEIN 2; 1.
DR Pfam; PF03772; Competence; 1.
DR Pfam; PF13567; DUF4131; 1.
DR Pfam; PF00753; Lactamase_B; 1.
DR SMART; SM00849; Lactamase_B; 1.
DR SUPFAM; SSF56281; Metallo-hydrolase/oxidoreductase; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000186950};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 6..25
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 32..50
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 56..74
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 257..278
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 285..304
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 355..372
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 384..408
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 420..442
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 449..471
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 477..497
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 518..535
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 548..750
FT /note="Metallo-beta-lactamase"
FT /evidence="ECO:0000259|SMART:SM00849"
SQ SEQUENCE 797 AA; 85971 MW; F6DDF134C5D3EEF4 CRC64;
MITEQINTII VFACAAFAAG IWQAGIYSWH SLTLIVLAVL LLLTALWRVV RNYQQAFWPI
IGLFFIAGML CANLDSIVPA DAISHHIGKT VTVTGIVDAV PEISQANTHG KQVRYVVKVQ
NVELEKTGAN SASSGKVRIN VLYKENGELA VYGDKITVYG KVRELRGYNN PGQIDMTVAL
KREGITARMS VQEQNIKLNT AYAGYSWRAA LADWQAGIVR ALQKVMPVND AAILTAVLFG
GYQGINKNVV DDFAATGLIH ILSVSGAHIA LVAGLIRWFG NQLRLGSRTT TVVAVLAIVF
YACISGFTPP VIRSMIMGII SLLAILVERE SYAPAALAIT ALGMLVYQPL LLYDISFQLS
FAATAGLVFL YKPTYDYLSA FLPAWLAGPL AVTASAQLGV LPIIAWYFNN FSLISFAANI
LVLPVVELVI ILGLTGVIIY TVVPVIGNLV FVISSLLIGL VMMLTALLAA VPYSSVYIPS
VGISGSAAYY LLLAWFYGWR PLAVPGPGQL VRQRPGTCAT TVMVIIGLLA VYTWYPRPLS
VHFIDVGQGD AALIITPRGK AVLVDTGGSF SSSNYDIGER VVAPYLKHYG VTTVDYLILT
HGHQDHAGGA AGIAGRVSVN KVMLPREEYS QAVQALVHTK PAIAIIPTYT DQRFQLDGVD
VGIEHAVGEN GRNQAVTGNE VSSVVRVSYG RHSFLITGDL EAKGEEALLA AKAVKPCTVL
KVGHHGSKTS TTAAFLQALD PEYAVISVGY ANRFGHPHPE TIRRLTDRQT VIYRTDTHGA
VVFKSDGRKL EVDTYIK
//
