ID A0A1U7MRF8_9MICO Unreviewed; 534 AA.
AC A0A1U7MRF8;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 24-JAN-2024, entry version 20.
DE SubName: Full=dTDP-glucose 4,6-dehydratase {ECO:0000313|EMBL:OLT21791.1};
GN ORFNames=BJF81_14670 {ECO:0000313|EMBL:OLT21791.1};
OS Ornithinimicrobium sp. CNJ-824.
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales;
OC Ornithinimicrobiaceae; Ornithinimicrobium.
OX NCBI_TaxID=1904966 {ECO:0000313|EMBL:OLT21791.1, ECO:0000313|Proteomes:UP000185694};
RN [1] {ECO:0000313|EMBL:OLT21791.1, ECO:0000313|Proteomes:UP000185694}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CNJ-824 {ECO:0000313|EMBL:OLT21791.1,
RC ECO:0000313|Proteomes:UP000185694};
RX PubMed=27902408; DOI=10.1099/mic.0.000386;
RA Schorn M.A., Alanjary M.M., Aguinaldo K., Korobeynikov A., Podell S.,
RA Patin N., Lincecum T., Jensen P.R., Ziemert N., Moore B.S.;
RT "Sequencing rare marine actinomycete genomes reveals high density of unique
RT natural product biosynthetic gene clusters.";
RL Microbiology 162:2075-2086(2016).
CC -!- SIMILARITY: Belongs to the polysaccharide synthase family.
CC {ECO:0000256|ARBA:ARBA00007430}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OLT21791.1}.
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DR EMBL; MKKA01000018; OLT21791.1; -; Genomic_DNA.
DR RefSeq; WP_075957959.1; NZ_MKKA01000018.1.
DR AlphaFoldDB; A0A1U7MRF8; -.
DR STRING; 1904966.BJF81_14670; -.
DR OrthoDB; 9803111at2; -.
DR Proteomes; UP000185694; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd05237; UDP_invert_4-6DH_SDR_e; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR003869; Polysac_CapD-like.
DR PANTHER; PTHR43318:SF1; POLYSACCHARIDE BIOSYNTHESIS PROTEIN EPSC-RELATED; 1.
DR PANTHER; PTHR43318; UDP-N-ACETYLGLUCOSAMINE 4,6-DEHYDRATASE; 1.
DR Pfam; PF13727; CoA_binding_3; 1.
DR Pfam; PF02719; Polysacc_synt_2; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 2.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000185694};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..31
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 37..57
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 219..497
FT /note="Polysaccharide biosynthesis protein CapD-like"
FT /evidence="ECO:0000259|Pfam:PF02719"
SQ SEQUENCE 534 AA; 58329 MW; 4614A14D1C6E1DDA CRC64;
MVRHMRGSFD EVTSVVKTAL ITGLAIIAIA WATPEVFLPR SVAVLAPALA IVLMLAVRFT
VRTYRSRQVA QNPDGERVIV LGAGLAGRRL ISNMLHDDRS EFAPVGLLDD DRSKRRLKIE
GIPVMGTRGD LAAVAERTQA RYLAVAIPRA DSDLLREIQE QTREAGLQVK TLPPIEQWLR
ASDPQATDLR DINLEDLLGR RAVELDQEAI ADHLTGKVVL VTGAGGSIGS ELCRQIQRFS
PARLVMLDRD ESALHAVQLS MTGRGLLEGE DLLLADIRDE ARLQDAFAEI RPDVVFHAAA
LKHLSLLERY PHEAWQTNVL GTRNVLHAAS AAGVGTFVNI STDKAARPTS VLGYSKRMAE
RLTAYYAETK PGRYVSVRFG NVLGSRGSVI PAFTEQIRRG GPVTVTHPDV ERYFMLIPEA
CQLVLQAGAI GRDGQVMVLD MGKPVKIVEV ARELISLSGR SIDIEFTGLR PGEKLTEVLF
TQGDSHVSVG HPAMTAVTVP PLSMETVQSS FSHSDASRFL MMHEGRGFNA PIEV
//
