ID A0A1U7Q423_MESAU Unreviewed; 489 AA.
AC A0A1U7Q423;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=LOW QUALITY PROTEIN: keratin, type II cytoskeletal 72 {ECO:0000313|RefSeq:XP_005067339.2};
GN Name=LOC101835741 {ECO:0000313|RefSeq:XP_005067339.2};
OS Mesocricetus auratus (Golden hamster).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea;
OC Cricetidae; Cricetinae; Mesocricetus.
OX NCBI_TaxID=10036 {ECO:0000313|Proteomes:UP000189706, ECO:0000313|RefSeq:XP_005067339.2};
RN [1] {ECO:0000313|RefSeq:XP_005067339.2}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the intermediate filament family.
CC {ECO:0000256|RuleBase:RU000685}.
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DR RefSeq; XP_005067339.2; XM_005067282.2.
DR STRING; 10036.ENSMAUP00000019134; -.
DR eggNOG; ENOG502T3SC; Eukaryota.
DR OrthoDB; 4640531at2759; -.
DR Proteomes; UP000189706; Unplaced.
DR GO; GO:0045095; C:keratin filament; IEA:InterPro.
DR Gene3D; 1.20.5.170; -; 1.
DR Gene3D; 1.20.5.500; Single helix bin; 1.
DR Gene3D; 1.20.5.1160; Vasodilator-stimulated phosphoprotein; 1.
DR InterPro; IPR018039; IF_conserved.
DR InterPro; IPR039008; IF_rod_dom.
DR InterPro; IPR032444; Keratin_2_head.
DR InterPro; IPR003054; Keratin_II.
DR PANTHER; PTHR45616; GATA-TYPE DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR45616:SF2; KERATIN, TYPE II CYTOSKELETAL 72; 1.
DR Pfam; PF00038; Filament; 1.
DR Pfam; PF16208; Keratin_2_head; 1.
DR PRINTS; PR01276; TYPE2KERATIN.
DR SMART; SM01391; Filament; 1.
DR SUPFAM; SSF64593; Intermediate filament protein, coiled coil region; 3.
DR PROSITE; PS00226; IF_ROD_1; 1.
DR PROSITE; PS51842; IF_ROD_2; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Intermediate filament {ECO:0000256|ARBA:ARBA00022754,
KW ECO:0000256|RuleBase:RU000685}; Keratin {ECO:0000256|ARBA:ARBA00022744};
KW Reference proteome {ECO:0000313|Proteomes:UP000189706}.
FT DOMAIN 134..447
FT /note="IF rod"
FT /evidence="ECO:0000259|PROSITE:PS51842"
FT COILED 189..237
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 366..425
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 489 AA; 54223 MW; 3660B112F66BDE44 CRC64;
MSRQLTLYPG AERLGFSGCS AVISGRFSSS HASVRAGVKG AAFGSKSLFC MGGGRRLALS
SAGRSGGFAL GHGGASSGRP GGFVGTIFGS AGLGPTCPSV CPPGGIPQVI VNKSLLAPLN
LELDPEIQKV RAQEREQIKA LNNKFASFID KVRFLEQQNQ VLETKWELLQ QLDLNNCKRS
LEPVYESYIS NLQKQLEILS GDRVRLDSEL RNMREVVEDC KKRYEVEINR RTAAENEFVV
LKKDVDAAYM NKVDLQAKVD SLTSDIKFFK VLYEGEIAQM QSHISDTSVV LSMDNNRQLD
LDSILTEVRA QYEEIAVKSK AETENMYQCK IQELQATVGQ HGDDLKLTKT EITEINRLIQ
RIHSEIGNVK KQCSNLETAI ADAEQRGDCA LKDARAKLDQ LEGALQQAKE ELARMMREHQ
ELMNVKLALD MEIATYRKLL ESEESRMNGD YSHSVSISIP SHSFSSAVAX ESWCCVRGLN
HFSYLQGDD
//
