ID   A0A1U7Q5S9_MESAU        Unreviewed;       244 AA.
AC   A0A1U7Q5S9;
DT   10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT   10-MAY-2017, sequence version 1.
DT   27-MAR-2024, entry version 25.
DE   RecName: Full=Fibroblast growth factor {ECO:0000256|RuleBase:RU049442};
DE            Short=FGF {ECO:0000256|RuleBase:RU049442};
GN   Name=Fgf8 {ECO:0000313|RefSeq:XP_005063583.1};
OS   Mesocricetus auratus (Golden hamster).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea;
OC   Cricetidae; Cricetinae; Mesocricetus.
OX   NCBI_TaxID=10036 {ECO:0000313|Proteomes:UP000189706, ECO:0000313|RefSeq:XP_005063583.1};
RN   [1] {ECO:0000313|RefSeq:XP_005063583.1}
RP   IDENTIFICATION.
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
CC   -!- SIMILARITY: Belongs to the heparin-binding growth factors family.
CC       {ECO:0000256|ARBA:ARBA00007936, ECO:0000256|RuleBase:RU049442}.
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DR   RefSeq; XP_005063583.1; XM_005063526.2.
DR   AlphaFoldDB; A0A1U7Q5S9; -.
DR   GeneID; 101830284; -.
DR   CTD; 2253; -.
DR   OrthoDB; 4098345at2759; -.
DR   Proteomes; UP000189706; Unplaced.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0008083; F:growth factor activity; IEA:UniProtKB-KW.
DR   CDD; cd00058; FGF; 1.
DR   Gene3D; 2.80.10.50; -; 1.
DR   InterPro; IPR002209; Fibroblast_GF_fam.
DR   InterPro; IPR008996; IL1/FGF.
DR   PANTHER; PTHR11486; FIBROBLAST GROWTH FACTOR; 1.
DR   PANTHER; PTHR11486:SF3; FIBROBLAST GROWTH FACTOR 8; 1.
DR   Pfam; PF00167; FGF; 1.
DR   PRINTS; PR00262; IL1HBGF.
DR   SMART; SM00442; FGF; 1.
DR   SUPFAM; SSF50353; Cytokine; 1.
DR   PROSITE; PS00247; HBGF_FGF; 1.
PE   3: Inferred from homology;
KW   Growth factor {ECO:0000256|ARBA:ARBA00023030};
KW   Reference proteome {ECO:0000313|Proteomes:UP000189706};
KW   Secreted {ECO:0000256|ARBA:ARBA00022525};
KW   Signal {ECO:0000256|RuleBase:RU049442}.
FT   SIGNAL          1..22
FT                   /evidence="ECO:0000256|RuleBase:RU049442"
FT   CHAIN           23..244
FT                   /note="Fibroblast growth factor"
FT                   /evidence="ECO:0000256|RuleBase:RU049442"
FT                   /id="PRO_5010399617"
SQ   SEQUENCE   244 AA;  27566 MW;  0990DD4BD7666BDD CRC64;
     MGSPRSALSC LLLHLLVLCL QAQEGPGGGP ALGREPASLL RAGREPQGVS QQVTVQSSPN
     FTQHVREQSL VTDQLSRRLI RTYQLYSRTS GKHVQVLANK RINAMAEDGD PFAKLIVETD
     TFGSRVRVRG AETGLYICMN KKGKLIAKSN GKGKDCVFTE IVLENNYTAL QNAKYEGWYM
     AFTRKGRPRK GSKTRQHQRE VHFMKRLPRG HHTTEQSLRF EFLNYPPFTR SLRGSQRTWA
     PEPR
//