ID A0A1U7QCW6_MESAU Unreviewed; 1057 AA.
AC A0A1U7QCW6;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE SubName: Full=Protocadherin-10 isoform X1 {ECO:0000313|RefSeq:XP_005069728.1};
GN Name=Pcdh10 {ECO:0000313|RefSeq:XP_005069728.1};
OS Mesocricetus auratus (Golden hamster).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea;
OC Cricetidae; Cricetinae; Mesocricetus.
OX NCBI_TaxID=10036 {ECO:0000313|Proteomes:UP000189706, ECO:0000313|RefSeq:XP_005069728.1};
RN [1] {ECO:0000313|RefSeq:XP_005069728.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_005069728.1; XM_005069671.3.
DR AlphaFoldDB; A0A1U7QCW6; -.
DR STRING; 10036.ENSMAUP00000001999; -.
DR GeneID; 101829160; -.
DR KEGG; maua:101829160; -.
DR CTD; 57575; -.
DR eggNOG; KOG3594; Eukaryota.
DR OrthoDB; 4259465at2759; -.
DR Proteomes; UP000189706; Unplaced.
DR GO; GO:0005886; C:plasma membrane; IEA:InterPro.
DR GO; GO:0005509; F:calcium ion binding; IEA:UniProtKB-UniRule.
DR GO; GO:0007156; P:homophilic cell adhesion via plasma membrane adhesion molecules; IEA:Ensembl.
DR CDD; cd11304; Cadherin_repeat; 6.
DR Gene3D; 2.60.40.60; Cadherins; 6.
DR InterPro; IPR002126; Cadherin-like_dom.
DR InterPro; IPR015919; Cadherin-like_sf.
DR InterPro; IPR032455; Cadherin_C.
DR InterPro; IPR020894; Cadherin_CS.
DR InterPro; IPR013164; Cadherin_N.
DR PANTHER; PTHR24028; CADHERIN-87A; 1.
DR PANTHER; PTHR24028:SF0; PROTOCADHERIN-10; 1.
DR Pfam; PF00028; Cadherin; 4.
DR Pfam; PF08266; Cadherin_2; 1.
DR Pfam; PF16492; Cadherin_C_2; 1.
DR PRINTS; PR00205; CADHERIN.
DR SMART; SM00112; CA; 6.
DR SUPFAM; SSF49313; Cadherin-like; 6.
DR PROSITE; PS00232; CADHERIN_1; 4.
DR PROSITE; PS50268; CADHERIN_2; 6.
PE 4: Predicted;
KW Calcium {ECO:0000256|ARBA:ARBA00022837, ECO:0000256|PROSITE-
KW ProRule:PRU00043}; Cell adhesion {ECO:0000256|ARBA:ARBA00022889};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000189706};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}; Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..18
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 19..1057
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5010545458"
FT TRANSMEM 714..738
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 16..122
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 123..250
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 251..358
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 359..463
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 464..574
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 590..680
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT REGION 685..708
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 899..930
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 908..924
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1057 AA; 114831 MW; 46B3019B866D0FC6 CRC64;
MIVLLFFALL WMVDGVFSQL HYTVQEEQEH GTFVGNIAED LGLDITKLSA RRFQTVANSR
TPYLDLNLET GVLYVNEKID REQICKQSPS CVLHLEVFLE NPLELFRVEI EVLDINDNPP
SFPEPDLTVE ISESATPGTR FPLESAFDPD VGTNSLRDYE ITPNSYFSLD VQTQGDGNRF
AELVLEKPLD REQQAVHRYV LTAVDGGGGG GGGEGGGGGG GVGLPPQQQR TGTALLTIRV
LDSNDNVPAF DQPVYTVSLP ENSPPGTLVI QLNATDPDEG QNGEVVYSFS SHISPRAREL
FGLSPRTGRL EVSGELDYEE SPVYQVYVQA KDLGPNAVPA HCKVLVRVLD ANDNAPEISF
STVKEAVSEG AAPGTVVALF SVTDRDSEEN GQVQCELLGD VPFRLKSSFK NYYTIVTEAP
LDREAGDSYT LTVVARDRGE PALSTSKSIQ VQVSDVNDNA PRFSQPVYDV YVTENNVPGA
YIYAVSATDR DEGANAKLTY SILECQIQGM SVFTYVSINS DNGYLYALRS FDYEQIKDFS
FQVEARDAGS PQALAGNATV NILIVDQNDN APAIVAPLPG RNGTPAREVL PRSAEPGYLL
TRVAAVDADD GENARLTYSI VRGNEMNLFR LDWRTGELRT ARRVPAKRDP QRPYELVIEV
RDHGQPPLSS TATLVVQLVD GAVEPQGGGG GGGGGPGEHQ RPSRSGGGET SLDLTLILII
ALGSVSFIFL LAMIVLAVRC QKEKKLNIYT CLASDCCLCC CCCGSGGPTC CGRQARARKK
KLSKSDIMLV QSANVPSNPA QVPVEETGSF GSHHHNQNYC YQVCLTPESA KTDLMFLKPC
SPSRSTDAEH NPCGAIVTGY SDQQPDIISN GSILSNENKH QRAELSYLVD RPRRVNSSAF
QEADIVSSKD SGHGDSEQGD SDHDVTNRGQ SAGMDLFSNC TEECKALGHS DRCWMPSFVP
SDGRQAADYR SNLHVPGMDS VPDTEVFEPP EAQPGAERSF STFGKEKALH GTLERKELDG
LLSNTRAPYK PPYLKTLWMQ LRGEAHLTKD GGKQPTT
//
