ID A0A1U7QHQ9_MESAU Unreviewed; 487 AA.
AC A0A1U7QHQ9;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=TOM1-like protein 2 isoform X5 {ECO:0000313|RefSeq:XP_005067735.1};
GN Name=Tom1l2 {ECO:0000313|RefSeq:XP_005067735.1};
OS Mesocricetus auratus (Golden hamster).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea;
OC Cricetidae; Cricetinae; Mesocricetus.
OX NCBI_TaxID=10036 {ECO:0000313|Proteomes:UP000189706, ECO:0000313|RefSeq:XP_005067735.1};
RN [1] {ECO:0000313|RefSeq:XP_005067735.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the TOM1 family. {ECO:0000256|ARBA:ARBA00007708,
CC ECO:0000256|PIRNR:PIRNR036948}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR RefSeq; XP_005067735.1; XM_005067678.3.
DR AlphaFoldDB; A0A1U7QHQ9; -.
DR GeneID; 101842855; -.
DR CTD; 146691; -.
DR OrthoDB; 609735at2759; -.
DR Proteomes; UP000189706; Unplaced.
DR GO; GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
DR GO; GO:0043130; F:ubiquitin binding; IEA:InterPro.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-UniRule.
DR CDD; cd14238; GAT_TM1L2; 1.
DR CDD; cd16996; VHS_Tom1L2; 1.
DR Gene3D; 1.20.58.160; -; 1.
DR Gene3D; 1.25.40.90; -; 1.
DR InterPro; IPR008942; ENTH_VHS.
DR InterPro; IPR004152; GAT_dom.
DR InterPro; IPR038425; GAT_sf.
DR InterPro; IPR014645; TOM1.
DR InterPro; IPR027429; TOM1L2_VHS_dom.
DR InterPro; IPR002014; VHS_dom.
DR PANTHER; PTHR13856:SF31; TOM1-LIKE PROTEIN 2; 1.
DR PANTHER; PTHR13856; VHS DOMAIN CONTAINING PROTEIN FAMILY; 1.
DR Pfam; PF03127; GAT; 1.
DR Pfam; PF00790; VHS; 1.
DR PIRSF; PIRSF036948; TOM1; 1.
DR SMART; SM00288; VHS; 1.
DR SUPFAM; SSF48464; ENTH/VHS domain; 1.
DR SUPFAM; SSF89009; GAT-like domain; 1.
DR PROSITE; PS50909; GAT; 1.
DR PROSITE; PS50179; VHS; 1.
PE 3: Inferred from homology;
KW Protein transport {ECO:0000256|ARBA:ARBA00022927,
KW ECO:0000256|PIRNR:PIRNR036948};
KW Reference proteome {ECO:0000313|Proteomes:UP000189706};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|PIRNR:PIRNR036948}.
FT DOMAIN 20..152
FT /note="VHS"
FT /evidence="ECO:0000259|PROSITE:PS50179"
FT DOMAIN 219..307
FT /note="GAT"
FT /evidence="ECO:0000259|PROSITE:PS50909"
FT REGION 163..201
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 414..487
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 177..201
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 422..452
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 487 AA; 53256 MW; A716AEDA796593D2 CRC64;
MEFLLGNPFS TPVGQCLEKA TDGSLQSEDW TLNMEICDII NETEEGPKDA IRALKKRLSG
NRNYREVMLA LTVLETCVKN CGHRFHLLVA NRDFIDSVLV KIISPKNNPP TIVQDKVLAL
IQAWADAFRS SPDLTGVVHI YEELKRKGVE FPMADLDALS PIHTPQRSVP EMDPAATMPR
SQSQPRTSAG THSSPPPASY SALQAPALSV TGPITANSEQ IARLRSELDV VRGNTKVMSE
MLTEMVPGQE DSSDLELLQE LNRTCRAMQH RIVELISRVS NEEVTEELLH VNDDLNNVFL
RYERFERYRS GRSVQNASNG VLSEVTEDNL IDLGPGSPAV VSPMVGSTAP PSSLSSQLAG
LDLGTESVSG TLSSLQQCKP HDGFDMFAQT RGNSLAEQRK TVTYEDPQAV GGLASALDNR
KQSSDMKGDD LEEGVTSEEF DKFLEERAKA AETVPDLPSP PTEAPAPASN TSNRKKPERS
EDALFAL
//
