ID   A0A1U7QJ20_MESAU        Unreviewed;       608 AA.
AC   A0A1U7QJ20;
DT   10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT   10-MAY-2017, sequence version 1.
DT   27-MAR-2024, entry version 25.
DE   SubName: Full=GRAM domain-containing protein 4 {ECO:0000313|RefSeq:XP_005067121.2};
GN   Name=Gramd4 {ECO:0000313|RefSeq:XP_005067121.2};
OS   Mesocricetus auratus (Golden hamster).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea;
OC   Cricetidae; Cricetinae; Mesocricetus.
OX   NCBI_TaxID=10036 {ECO:0000313|Proteomes:UP000189706, ECO:0000313|RefSeq:XP_005067121.2};
RN   [1] {ECO:0000313|RefSeq:XP_005067121.2}
RP   IDENTIFICATION.
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   RefSeq; XP_005067121.2; XM_005067064.3.
DR   AlphaFoldDB; A0A1U7QJ20; -.
DR   STRING; 10036.ENSMAUP00000025609; -.
DR   GeneID; 101828428; -.
DR   KEGG; maua:101828428; -.
DR   CTD; 23151; -.
DR   eggNOG; ENOG502QPMR; Eukaryota.
DR   OrthoDB; 3028864at2759; -.
DR   Proteomes; UP000189706; Unplaced.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0006915; P:apoptotic process; IEA:InterPro.
DR   CDD; cd13221; PH-GRAM_GRAMDC4; 1.
DR   Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR   InterPro; IPR004182; GRAM.
DR   InterPro; IPR037847; GRAMDC4.
DR   InterPro; IPR037845; GRAMDC4_PH-GRAM.
DR   InterPro; IPR011993; PH-like_dom_sf.
DR   PANTHER; PTHR37402; GRAM DOMAIN-CONTAINING PROTEIN 4; 1.
DR   PANTHER; PTHR37402:SF1; GRAM DOMAIN-CONTAINING PROTEIN 4; 1.
DR   Pfam; PF02893; GRAM; 1.
DR   SMART; SM00568; GRAM; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000189706};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        276..298
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          475..553
FT                   /note="GRAM"
FT                   /evidence="ECO:0000259|SMART:SM00568"
FT   REGION          47..84
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          157..191
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        161..191
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   608 AA;  69473 MW;  DC6431AE32371623 CRC64;
     MRVGPDLPAG EASRHVQVRP RSAVLNMLRR LDRIRFRGHR REDFLDLAES PNASDTECGD
     EIPLKTPRPS PRDSEELRDP AGPGTLIMAA GVQDFSRTEF DRLNEIKGHL EIALLEKHFL
     QEELRKLREE TNSEMLRQEL DRERQRRIEL EQKMQEVLKA RSEEQPTQPQ QPPKGQSQAS
     NGTGTDRSSQ GLSARVQKWF YERFGEYVED FRFQPEENTV ETEEPLSARR LTENMRRLKR
     GAKPVTNFVK NLSALSDWYS IYTSAIAFTV YMNAVWHGWA IPMFLFLAIL RLSLNYLIAR
     GWRIQWSIVP EVSEAVEPAK EDLTVSEKFQ LVLDVAQKAQ NLFGKMADIL EKIKNLFMWV
     QPEITQKLYV ALWAAFLASC FFPYRLVGLA VGLYAGIKFF LIDFIFKRCP RLRAKYDTPY
     IIWKNLPTDP QLKERAGATV SRRLQTTSSR SYVSSAPAGL SKDEDAGRFH STKKGNFHEI
     FNLTENERPL AVCENGWRCC LINRDRKMPT DYIRNGVLYV TENYLCFESS KSGSSKRNKV
     IKLADITDIQ KYKVLSVLPG SGMGIAVSTP STQKPLVFGA MVHRDEAFET IFSQYVKITS
     AAASGGDS
//