ID A0A1U7QJR3_MESAU Unreviewed; 613 AA.
AC A0A1U7QJR3;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE SubName: Full=T-box transcription factor TBX18 {ECO:0000313|RefSeq:XP_005073719.1};
GN Name=Tbx18 {ECO:0000313|RefSeq:XP_005073719.1};
OS Mesocricetus auratus (Golden hamster).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea;
OC Cricetidae; Cricetinae; Mesocricetus.
OX NCBI_TaxID=10036 {ECO:0000313|Proteomes:UP000189706, ECO:0000313|RefSeq:XP_005073719.1};
RN [1] {ECO:0000313|RefSeq:XP_005073719.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|PROSITE-ProRule:PRU00201}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00201}.
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DR RefSeq; XP_005073719.1; XM_005073662.3.
DR AlphaFoldDB; A0A1U7QJR3; -.
DR STRING; 10036.ENSMAUP00000010180; -.
DR GeneID; 101832368; -.
DR KEGG; maua:101832368; -.
DR CTD; 9096; -.
DR eggNOG; KOG3586; Eukaryota.
DR OrthoDB; 5323209at2759; -.
DR Proteomes; UP000189706; Unplaced.
DR GO; GO:0005654; C:nucleoplasm; IEA:Ensembl.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IEA:InterPro.
DR GO; GO:0045893; P:positive regulation of DNA-templated transcription; IEA:InterPro.
DR GO; GO:0098907; P:regulation of SA node cell action potential; IEA:Ensembl.
DR GO; GO:0060931; P:sinoatrial node cell development; IEA:Ensembl.
DR GO; GO:0060930; P:sinoatrial node cell fate commitment; IEA:Ensembl.
DR GO; GO:0072189; P:ureter development; IEA:Ensembl.
DR CDD; cd20191; T-box_TBX15_18_22-like; 1.
DR Gene3D; 2.60.40.820; Transcription factor, T-box; 1.
DR InterPro; IPR008967; p53-like_TF_DNA-bd_sf.
DR InterPro; IPR046360; T-box_DNA-bd.
DR InterPro; IPR036960; T-box_sf.
DR InterPro; IPR001699; TF_T-box.
DR InterPro; IPR018186; TF_T-box_CS.
DR PANTHER; PTHR11267; T-BOX PROTEIN-RELATED; 1.
DR PANTHER; PTHR11267:SF20; T-BOX TRANSCRIPTION FACTOR TBX18; 1.
DR Pfam; PF00907; T-box; 1.
DR PRINTS; PR00937; TBOX.
DR SMART; SM00425; TBOX; 1.
DR SUPFAM; SSF49417; p53-like transcription factors; 1.
DR PROSITE; PS01283; TBOX_1; 1.
DR PROSITE; PS01264; TBOX_2; 1.
DR PROSITE; PS50252; TBOX_3; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU00201};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW ProRule:PRU00201}; Reference proteome {ECO:0000313|Proteomes:UP000189706};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 149..336
FT /note="T-box"
FT /evidence="ECO:0000259|PROSITE:PS50252"
FT REGION 30..85
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 114..142
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 32..46
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 613 AA; 65530 MW; 70563378B99231FA CRC64;
MAEKRRGSPC SMLSLKAHAF SVEALIGAEK QQQLQKKRRK LTTEEAAGAP DDAGCSRGGG
VGDQGCSEAD EDAAPPPLPA GAASGTARSC ADVERSCGSR GAAGSCEDGF LQGASPLASP
RGSPKGSPVP GLARTGTPLP ALQAPRVDLQ GAELWKRFHE IGTEMIITKA GRRMFPAMRV
KISGLDPHQQ YYIAMDIVPV DNKRYRYVYH SSKWMVAGNA DSPVPPRVYI HPDSPASGET
WMRQVVSFDK LKLTNNELDD QGHIILHSMH KYQPRVHVIR KDCGDDLSPI KPVPSGEGVK
AFSFPETVFT TVTAYQNQQI TRLKIDRNPF AKGFRDSGRN RMGLEALVES YAFWRPSLRT
LTFEDIPGIP KQGNTSSSTL LQGTGNGVPA AHPHLLSGSS CSSPAFHLGP NTSQLCSLAP
ADYSACARSG LALNRYSTSL AETYNRLTNQ GSETFAPPRT PSYVGVSSSP SVNMSMGGTD
GDTFSCPQTS LSMQISGMSP QLQYIMPSPS SNAFAANQTH QGSYNTFRLH SPCALYGYNF
STSPKLAASP EKIVSSQGSF LGSSPSGTMT DRQMLPPVEG VHLLSSGGQQ SFFDSRTLGS
LTLSSSQVSA HMV
//
