ID A0A1U7QJX5_MESAU Unreviewed; 237 AA.
AC A0A1U7QJX5;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE RecName: Full=Ferritin {ECO:0000256|RuleBase:RU361145};
GN Name=Ftmt {ECO:0000313|RefSeq:XP_005069181.1};
OS Mesocricetus auratus (Golden hamster).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea;
OC Cricetidae; Cricetinae; Mesocricetus.
OX NCBI_TaxID=10036 {ECO:0000313|Proteomes:UP000189706, ECO:0000313|RefSeq:XP_005069181.1};
RN [1] {ECO:0000313|RefSeq:XP_005069181.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- FUNCTION: Stores iron in a soluble, non-toxic, readily available form.
CC Important for iron homeostasis. Iron is taken up in the ferrous form
CC and deposited as ferric hydroxides after oxidation.
CC {ECO:0000256|RuleBase:RU361145}.
CC -!- SIMILARITY: Belongs to the ferritin family.
CC {ECO:0000256|ARBA:ARBA00007513, ECO:0000256|RuleBase:RU361145}.
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DR RefSeq; XP_005069181.1; XM_005069124.2.
DR AlphaFoldDB; A0A1U7QJX5; -.
DR STRING; 10036.ENSMAUP00000019395; -.
DR GeneID; 101828443; -.
DR KEGG; maua:101828443; -.
DR CTD; 94033; -.
DR eggNOG; KOG2332; Eukaryota.
DR OrthoDB; 4611704at2759; -.
DR Proteomes; UP000189706; Unplaced.
DR GO; GO:0005739; C:mitochondrion; IEA:Ensembl.
DR GO; GO:0008199; F:ferric iron binding; IEA:InterPro.
DR GO; GO:0004322; F:ferroxidase activity; IEA:Ensembl.
DR GO; GO:0006879; P:intracellular iron ion homeostasis; IEA:UniProtKB-KW.
DR GO; GO:0006826; P:iron ion transport; IEA:InterPro.
DR GO; GO:0008284; P:positive regulation of cell population proliferation; IEA:Ensembl.
DR CDD; cd01056; Euk_Ferritin; 1.
DR Gene3D; 1.20.1260.10; -; 1.
DR InterPro; IPR001519; Ferritin.
DR InterPro; IPR012347; Ferritin-like.
DR InterPro; IPR009040; Ferritin-like_diiron.
DR InterPro; IPR009078; Ferritin-like_SF.
DR InterPro; IPR014034; Ferritin_CS.
DR InterPro; IPR008331; Ferritin_DPS_dom.
DR PANTHER; PTHR11431; FERRITIN; 1.
DR PANTHER; PTHR11431:SF30; FERRITIN, MITOCHONDRIAL; 1.
DR Pfam; PF00210; Ferritin; 1.
DR SUPFAM; SSF47240; Ferritin-like; 1.
DR PROSITE; PS00540; FERRITIN_1; 1.
DR PROSITE; PS00204; FERRITIN_2; 1.
DR PROSITE; PS50905; FERRITIN_LIKE; 1.
PE 3: Inferred from homology;
KW Iron {ECO:0000256|ARBA:ARBA00023004, ECO:0000256|RuleBase:RU361145};
KW Iron storage {ECO:0000256|ARBA:ARBA00022434,
KW ECO:0000256|RuleBase:RU361145};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723,
KW ECO:0000256|RuleBase:RU361145};
KW Reference proteome {ECO:0000313|Proteomes:UP000189706}.
FT DOMAIN 66..215
FT /note="Ferritin-like diiron"
FT /evidence="ECO:0000259|PROSITE:PS50905"
SQ SEQUENCE 237 AA; 26868 MW; 071509C40FDBEBFE CRC64;
MLSCFWFFSK HIGPALMSLP RVLHRCTVPP CLAARYPLGT IPVSPRRLLA SVASSQGSAG
PARVRQNFHP DSEAAINRQI NMELYASYVY LSMAYYFSRD DVALYNFSKY FLRQSLEERE
HAEKLMRLQN QRGGRICLQD IKKPDQDDWE SGLRAMECAL LLEKSVNQSL LDLHTLASEK
GDPHLCDFLE THYLNEQVKS IKELGDHVHN LVTMGAPAAG LAEYLFDKHT LGSESKH
//
