ID A0A1U7QKA1_MESAU Unreviewed; 260 AA.
AC A0A1U7QKA1;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE RecName: Full=Endoplasmic reticulum resident protein 29 {ECO:0000256|ARBA:ARBA00014173, ECO:0000256|PIRNR:PIRNR027352};
GN Name=Erp29 {ECO:0000313|RefSeq:XP_005080707.1};
OS Mesocricetus auratus (Golden hamster).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea;
OC Cricetidae; Cricetinae; Mesocricetus.
OX NCBI_TaxID=10036 {ECO:0000313|Proteomes:UP000189706, ECO:0000313|RefSeq:XP_005080707.1};
RN [1] {ECO:0000313|RefSeq:XP_005080707.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- FUNCTION: Does not seem to be a disulfide isomerase.
CC {ECO:0000256|PIRNR:PIRNR027352}.
CC -!- SUBUNIT: Homodimer. {ECO:0000256|PIRNR:PIRNR027352}.
CC -!- SUBCELLULAR LOCATION: Endoplasmic reticulum lumen
CC {ECO:0000256|PIRNR:PIRNR027352}. Melanosome
CC {ECO:0000256|PIRNR:PIRNR027352}.
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DR RefSeq; XP_005080707.1; XM_005080650.3.
DR AlphaFoldDB; A0A1U7QKA1; -.
DR STRING; 10036.ENSMAUP00000017453; -.
DR GeneID; 101832481; -.
DR KEGG; maua:101832481; -.
DR CTD; 10961; -.
DR eggNOG; ENOG502QSHC; Eukaryota.
DR OrthoDB; 5403558at2759; -.
DR Proteomes; UP000189706; Unplaced.
DR GO; GO:0009986; C:cell surface; IEA:Ensembl.
DR GO; GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.
DR GO; GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.
DR GO; GO:0010629; P:negative regulation of gene expression; IEA:Ensembl.
DR GO; GO:0050709; P:negative regulation of protein secretion; IEA:Ensembl.
DR GO; GO:0010628; P:positive regulation of gene expression; IEA:Ensembl.
DR GO; GO:0001934; P:positive regulation of protein phosphorylation; IEA:Ensembl.
DR GO; GO:0009306; P:protein secretion; IEA:InterPro.
DR GO; GO:1902235; P:regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway; IEA:Ensembl.
DR CDD; cd00238; ERp29c; 1.
DR CDD; cd03007; PDI_a_ERp29_N; 1.
DR Gene3D; 1.20.1150.12; Endoplasmic reticulum resident protein 29, C-terminal domain; 1.
DR Gene3D; 3.40.30.10; Glutaredoxin; 1.
DR InterPro; IPR016855; ERp29.
DR InterPro; IPR011679; ERp29_C.
DR InterPro; IPR036356; ERp29_C_sf.
DR InterPro; IPR012883; ERp29_N.
DR InterPro; IPR036249; Thioredoxin-like_sf.
DR PANTHER; PTHR12211; ENDOPLASMIC RETICULUM PROTEIN ERP29; 1.
DR PANTHER; PTHR12211:SF0; ENDOPLASMIC RETICULUM RESIDENT PROTEIN 29; 1.
DR Pfam; PF07749; ERp29; 1.
DR Pfam; PF07912; ERp29_N; 1.
DR PIRSF; PIRSF027352; ER_p29; 1.
DR SUPFAM; SSF47933; ERP29 C domain-like; 1.
DR SUPFAM; SSF52833; Thioredoxin-like; 1.
PE 4: Predicted;
KW Endoplasmic reticulum {ECO:0000256|ARBA:ARBA00022824,
KW ECO:0000256|PIRNR:PIRNR027352};
KW Reference proteome {ECO:0000313|Proteomes:UP000189706};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..32
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 33..260
FT /note="Endoplasmic reticulum resident protein 29"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5010553548"
FT DOMAIN 33..155
FT /note="ERp29 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF07912"
FT DOMAIN 156..250
FT /note="Endoplasmic reticulum resident protein 29 C-
FT terminal"
FT /evidence="ECO:0000259|Pfam:PF07749"
SQ SEQUENCE 260 AA; 28636 MW; 89B56EF7FC808A9F CRC64;
MAAAVPGAVS LSPLLSILLG LLLLSAPHGG SGLHTKGALP LDTITFYKVI PKSKFVLVKF
DTQYPYGEKQ DEFKRLAENS ASSDDLLVAE VGISDYGDKL NMELSEKYKL DKENYPVFYL
FQNGDFENPI PYSGAIKVGA IQRWLKGQGV YLGMPGCLPA YDALAGEFIK ASSVEARQAI
LKQGQDGLSG VKETEKKWAS QYLKIMGKIL DQGEDFPASE MTRISKLIEN KMSDSKKEEL
QKSLNILTAF RKKGVEKEEL
//
