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Database: UniProt
Entry: A0A1U7QMZ4_MESAU
LinkDB: A0A1U7QMZ4_MESAU
Original site: A0A1U7QMZ4_MESAU 
ID   A0A1U7QMZ4_MESAU        Unreviewed;       668 AA.
AC   A0A1U7QMZ4;
DT   10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT   10-MAY-2017, sequence version 1.
DT   10-OCT-2018, entry version 10.
DE   SubName: Full=protein-glutamine gamma-glutamyltransferase 4 {ECO:0000313|RefSeq:XP_005082423.1};
GN   Name=Tgm4 {ECO:0000313|RefSeq:XP_005082423.1};
OS   Mesocricetus auratus (Golden hamster).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
OC   Muroidea; Cricetidae; Cricetinae; Mesocricetus.
OX   NCBI_TaxID=10036 {ECO:0000313|Proteomes:UP000189706, ECO:0000313|RefSeq:XP_005082423.1};
RN   [1] {ECO:0000313|RefSeq:XP_005082423.1}
RP   IDENTIFICATION.
RG   RefSeq;
RL   Submitted (JUN-2017) to UniProtKB.
CC   -!- COFACTOR:
CC       Name=Ca(2+); Xref=ChEBI:CHEBI:29108;
CC         Evidence={ECO:0000256|PIRSR:PIRSR000459-2};
CC       Note=Binds 1 Ca(2+) ion per subunit.
CC       {ECO:0000256|PIRSR:PIRSR000459-2};
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DR   RefSeq; XP_005082423.1; XM_005082366.1.
DR   Ensembl; ENSMAUT00000017259; ENSMAUP00000013349; ENSMAUG00000013411.
DR   GeneID; 101833014; -.
DR   CTD; 7047; -.
DR   Proteomes; UP000189706; Genome assembly.
DR   GO; GO:0031012; C:extracellular matrix; IEA:Ensembl.
DR   GO; GO:0005794; C:Golgi apparatus; IEA:Ensembl.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003810; F:protein-glutamine gamma-glutamyltransferase activity; IEA:InterPro.
DR   GO; GO:0018149; P:peptide cross-linking; IEA:InterPro.
DR   Gene3D; 2.60.40.10; -; 3.
DR   Gene3D; 3.90.260.10; -; 1.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR014756; Ig_E-set.
DR   InterPro; IPR038765; Papain_like_cys_pep_sf.
DR   InterPro; IPR002931; Transglutaminase-like.
DR   InterPro; IPR036985; Transglutaminase-like_sf.
DR   InterPro; IPR023608; Transglutaminase_animal.
DR   InterPro; IPR008958; Transglutaminase_C.
DR   InterPro; IPR036238; Transglutaminase_C_sf.
DR   InterPro; IPR001102; Transglutaminase_N.
DR   Pfam; PF00927; Transglut_C; 1.
DR   Pfam; PF01841; Transglut_core; 1.
DR   Pfam; PF00868; Transglut_N; 1.
DR   PIRSF; PIRSF000459; TGM_EBP42; 1.
DR   SMART; SM00460; TGc; 1.
DR   SUPFAM; SSF49309; SSF49309; 2.
DR   SUPFAM; SSF54001; SSF54001; 1.
DR   SUPFAM; SSF81296; SSF81296; 1.
PE   4: Predicted;
KW   Calcium {ECO:0000256|PIRSR:PIRSR000459-2};
KW   Complete proteome {ECO:0000313|Proteomes:UP000189706};
KW   Metal-binding {ECO:0000256|PIRSR:PIRSR000459-2};
KW   Reference proteome {ECO:0000313|Proteomes:UP000189706};
KW   Transferase {ECO:0000313|RefSeq:XP_005082423.1}.
FT   DOMAIN      246    339       TGc. {ECO:0000259|SMART:SM00460}.
FT   ACT_SITE    254    254       {ECO:0000256|PIRSR:PIRSR000459-1}.
FT   ACT_SITE    313    313       {ECO:0000256|PIRSR:PIRSR000459-1}.
FT   ACT_SITE    336    336       {ECO:0000256|PIRSR:PIRSR000459-1}.
FT   METAL       376    376       Calcium. {ECO:0000256|PIRSR:PIRSR000459-
FT                                2}.
FT   METAL       378    378       Calcium. {ECO:0000256|PIRSR:PIRSR000459-
FT                                2}.
FT   METAL       428    428       Calcium. {ECO:0000256|PIRSR:PIRSR000459-
FT                                2}.
FT   METAL       433    433       Calcium. {ECO:0000256|PIRSR:PIRSR000459-
FT                                2}.
SQ   SEQUENCE   668 AA;  75072 MW;  1746C89FB9680322 CRC64;
     MDTSNALEVS SVNWKKTENT AAHHTSAFQI DKLVLRRGQI FNLKVTLNRP LQPQDEMKLE
     FSTGKNSSPY VELDPMTSFR SQGWQVKIAK QSGSKVTLSI ISAADAVVGQ YSLHMNSYNA
     GVFLLIFNPW CADDTVYLPS EEEREEYILN DTGYIYMGFA KQIKEKPWTF GQFEENILDC
     CIYLLDNLDP HELHSPVSVS RAICTMMCSV NNGVLMGNWS GDYKGGTAPY VWTSSVPILQ
     QHFATKSPVC FGQCWVFSGI LTTALRAMGI PARSVTNFES AHDTGKNLTV DIYLDESGKT
     IADLTKDSIW NFHVWTDAWM KRPDLPLGHD GWQVLDATPQ EVSEGRFRTG PSPLSAIRQG
     AVQIQYDTKF VFTEVNGDKF IWLVKQNQDK EKNILIAVET ASIGKNISTK MVGENKREDV
     TLQYKFPEGS PEERKAMENA SGKHLDEDKP NHPSSHGLKI YVLQNSVELG YPITLTLVLK
     RKTEVLQNVN ISCSLDLQTY TGSNKTNLGI IQKTVQVQGQ ESEVILNMDA NSYIYKLGMV
     DDEMVIKGFI IAEVMETGDK VATDMILSFL YPAFSVEMPD TGKVSWPLTI KCSFKNTLPI
     PLTEIRFSVE SLALSHMQSW EHGTLLPGKF IHFQMKCTPE KTGPRKFIVK FTSRQVKEVH
     SEKIVLIT
//
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