ID A0A1U7QND2_MESAU Unreviewed; 579 AA.
AC A0A1U7QND2;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=ETS-related transcription factor Elf-2 isoform X2 {ECO:0000313|RefSeq:XP_005077546.1};
GN Name=Elf2 {ECO:0000313|RefSeq:XP_005077546.1};
OS Mesocricetus auratus (Golden hamster).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea;
OC Cricetidae; Cricetinae; Mesocricetus.
OX NCBI_TaxID=10036 {ECO:0000313|Proteomes:UP000189706, ECO:0000313|RefSeq:XP_005077546.1};
RN [1] {ECO:0000313|RefSeq:XP_005077546.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|RuleBase:RU004019}.
CC -!- SIMILARITY: Belongs to the ETS family. {ECO:0000256|ARBA:ARBA00005562,
CC ECO:0000256|RuleBase:RU004019}.
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DR RefSeq; XP_005077546.1; XM_005077489.3.
DR AlphaFoldDB; A0A1U7QND2; -.
DR GeneID; 101828919; -.
DR CTD; 1998; -.
DR OrthoDB; 4245771at2759; -.
DR Proteomes; UP000189706; Unplaced.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IEA:InterPro.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR000418; Ets_dom.
DR InterPro; IPR046328; ETS_fam.
DR InterPro; IPR022084; TF_Elf_N.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR11849; ETS; 1.
DR PANTHER; PTHR11849:SF10; ETS-RELATED TRANSCRIPTION FACTOR ELF-2; 1.
DR Pfam; PF12310; Elf-1_N; 1.
DR Pfam; PF00178; Ets; 1.
DR PRINTS; PR00454; ETSDOMAIN.
DR SMART; SM00413; ETS; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS00345; ETS_DOMAIN_1; 1.
DR PROSITE; PS00346; ETS_DOMAIN_2; 1.
DR PROSITE; PS50061; ETS_DOMAIN_3; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|RuleBase:RU004019};
KW Nucleus {ECO:0000256|RuleBase:RU004019};
KW Reference proteome {ECO:0000313|Proteomes:UP000189706}.
FT DOMAIN 196..278
FT /note="ETS"
FT /evidence="ECO:0000259|PROSITE:PS50061"
FT REGION 1..30
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 135..187
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 579 AA; 61745 MW; 47403B0B8A60E19F CRC64;
MASAVVDSGG SVLELSSSGV ENKEGGDKVP EYPAVIVEPV PSARLEQGYA AQVLVYDDGT
YVMQDVAEEQ EVETENSEPV EASVHSSNAH CTDKTIEAAE ALLHMESPTC LRESRSPEFI
HAAMRPDVIT ETVVEVSTEE SEPMDASPIP TSPESHEPMK KKKVGRKPKT QQSPVSNGSP
ELGIKKKARE GKGNTTYLWE FLLDLLQDKN TCPRYIKWTQ REKGIFKLVD SKAVSKLWGK
HKNKPDMNYE TMGRALRYYY QRGILAKVEG QRLVYQFKDM PKNIVVIDDD TSEPCSEDLA
AAADEKSLER VSLSAESLLK AATSVRGGKS ASVNCSRAER GVARVVNVTS PAQDASPRSP
TTPASVPAAA PRTVRVAMQV PVVMTSLGQK ISTVAVQSVN AGAPLITSTS PTTATSPKVV
IQTIPTVVPA SAENGDKITM QPAKIITIPA TQLAQCQLQT KSNLTGSGSI NIVGAPLAVR
ALTPVSIAHG TPVMRLSVPA QQASGQTPPR VISAVIKGPE AKSEAVAKKQ EHDVKTLQLV
EEKGADGNKT VTHVVVVSAP SAIALPVTVK PEGLVTCDK
//
