ID A0A1U7QRI8_MESAU Unreviewed; 174 AA.
AC A0A1U7QRI8;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=Tumor necrosis factor ligand superfamily member 18 {ECO:0000313|RefSeq:XP_005071526.1};
GN Name=Tnfsf18 {ECO:0000313|RefSeq:XP_005071526.1};
OS Mesocricetus auratus (Golden hamster).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea;
OC Cricetidae; Cricetinae; Mesocricetus.
OX NCBI_TaxID=10036 {ECO:0000313|Proteomes:UP000189706, ECO:0000313|RefSeq:XP_005071526.1};
RN [1] {ECO:0000313|RefSeq:XP_005071526.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the tumor necrosis factor family.
CC {ECO:0000256|ARBA:ARBA00008670}.
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DR RefSeq; XP_005071526.1; XM_005071469.3.
DR AlphaFoldDB; A0A1U7QRI8; -.
DR STRING; 10036.ENSMAUP00000010578; -.
DR GeneID; 101832448; -.
DR KEGG; maua:101832448; -.
DR CTD; 8995; -.
DR eggNOG; ENOG502SWIC; Eukaryota.
DR OrthoDB; 5263857at2759; -.
DR Proteomes; UP000189706; Unplaced.
DR GO; GO:0009986; C:cell surface; IEA:Ensembl.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0042802; F:identical protein binding; IEA:Ensembl.
DR GO; GO:0005164; F:tumor necrosis factor receptor binding; IEA:InterPro.
DR GO; GO:2000329; P:negative regulation of T-helper 17 cell lineage commitment; IEA:Ensembl.
DR GO; GO:0045785; P:positive regulation of cell adhesion; IEA:Ensembl.
DR GO; GO:0050729; P:positive regulation of inflammatory response; IEA:Ensembl.
DR GO; GO:0010759; P:positive regulation of macrophage chemotaxis; IEA:Ensembl.
DR GO; GO:0090026; P:positive regulation of monocyte chemotaxis; IEA:Ensembl.
DR GO; GO:2000508; P:regulation of dendritic cell chemotaxis; IEA:Ensembl.
DR GO; GO:0043254; P:regulation of protein-containing complex assembly; IEA:Ensembl.
DR GO; GO:0042129; P:regulation of T cell proliferation; IEA:Ensembl.
DR GO; GO:0002309; P:T cell proliferation involved in immune response; IEA:Ensembl.
DR GO; GO:0033209; P:tumor necrosis factor-mediated signaling pathway; IEA:Ensembl.
DR Gene3D; 2.60.120.40; -; 1.
DR InterPro; IPR006052; TNF_dom.
DR InterPro; IPR042380; TNFSF18.
DR InterPro; IPR008983; Tumour_necrosis_fac-like_dom.
DR PANTHER; PTHR15267; TUMOR NECROSIS FACTOR LIGAND SUPERFAMILY MEMBER 18; 1.
DR PANTHER; PTHR15267:SF1; TUMOR NECROSIS FACTOR LIGAND SUPERFAMILY MEMBER 18; 1.
DR Pfam; PF00229; TNF; 1.
DR SUPFAM; SSF49842; TNF-like; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000189706};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 21..45
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 78..166
FT /note="TNF family profile"
FT /evidence="ECO:0000259|Pfam:PF00229"
SQ SEQUENCE 174 AA; 19604 MW; CF9208BBE6BCF5B7 CRC64;
MEQIPLNPPS PRRGAQRFRR PWLLCVVPLL LLLSYTTGAL IFSSLKPTAK EPCMVKFELS
PSKWHMTSPQ PFCVNMTSDG KLEILQDGVY LIYGQVTPVN KEDIKIPVDF IVELVKEGDV
LQSATNDFQV ITIGGIYELH AGDSIYLKFN SDDHVQKNNT YWGIVLMPDL SFSS
//
