ID A0A1U7QUB8_MESAU Unreviewed; 617 AA.
AC A0A1U7QUB8;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE SubName: Full=Zinc finger protein 276 isoform X1 {ECO:0000313|RefSeq:XP_005073210.1};
GN Name=Znf276 {ECO:0000313|RefSeq:XP_005073210.1};
OS Mesocricetus auratus (Golden hamster).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea;
OC Cricetidae; Cricetinae; Mesocricetus.
OX NCBI_TaxID=10036 {ECO:0000313|Proteomes:UP000189706, ECO:0000313|RefSeq:XP_005073210.1};
RN [1] {ECO:0000313|RefSeq:XP_005073210.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR RefSeq; XP_005073210.1; XM_005073153.3.
DR AlphaFoldDB; A0A1U7QUB8; -.
DR STRING; 10036.ENSMAUP00000018962; -.
DR GeneID; 101829431; -.
DR KEGG; maua:101829431; -.
DR CTD; 92822; -.
DR eggNOG; KOG1721; Eukaryota.
DR OrthoDB; 5315505at2759; -.
DR Proteomes; UP000189706; Unplaced.
DR GO; GO:0000776; C:kinetochore; IEA:Ensembl.
DR GO; GO:0005634; C:nucleus; IEA:InterPro.
DR GO; GO:1990837; F:sequence-specific double-stranded DNA binding; IEA:Ensembl.
DR GO; GO:0008270; F:zinc ion binding; IEA:UniProtKB-UniRule.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 4.
DR InterPro; IPR012934; Znf_AD.
DR InterPro; IPR036236; Znf_C2H2_sf.
DR InterPro; IPR013087; Znf_C2H2_type.
DR PANTHER; PTHR23235; KRUEPPEL-LIKE TRANSCRIPTION FACTOR; 1.
DR PANTHER; PTHR23235:SF149; LOW QUALITY PROTEIN: ZINC FINGER PROTEIN 239-RELATED; 1.
DR Pfam; PF07776; zf-AD; 1.
DR Pfam; PF00096; zf-C2H2; 2.
DR SMART; SM00355; ZnF_C2H2; 5.
DR SUPFAM; SSF57667; beta-beta-alpha zinc fingers; 2.
DR PROSITE; PS51915; ZAD; 1.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 3.
DR PROSITE; PS50157; ZINC_FINGER_C2H2_2; 4.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Metal-binding {ECO:0000256|PROSITE-ProRule:PRU01263};
KW Reference proteome {ECO:0000313|Proteomes:UP000189706};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU01263};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00042}.
FT DOMAIN 81..167
FT /note="ZAD"
FT /evidence="ECO:0000259|PROSITE:PS51915"
FT DOMAIN 468..498
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 499..526
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 527..554
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 557..585
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT REGION 1..43
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 273..298
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 321..427
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 590..617
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 14..31
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 275..298
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 349..427
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 83
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01263"
FT BINDING 86
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01263"
FT BINDING 140
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01263"
FT BINDING 143
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01263"
SQ SEQUENCE 617 AA; 67927 MW; F4E040B8852F8273 CRC64;
MKRDRLGRFL SPGTARQRGS SGGSCGSGRT RGRPSRTGGA SADGAAALTA AQLSWGSTRS
CGDTGEDGTD EAGAGRTLAM GHCRLCHGKF SSRSLRSISD RVPGETSERL SRGERVFIRD
FQRLLGVAVH QDPALPQFVC KSCYTQFYQC HSLLRSFLQR VNVSPAGQRK PCTKVGVQPP
TVAEEGACMA DLITSSPRCL HSLVGWVHEH AASCGSLPSL QRTLSSEYCG IIQAVWGCDQ
GHDFTMDTDS SCRALFLDSA LAVRWAWGKE MPPRLSQNSE LNTTGAASQL CQARETQAAS
ETKTLPSVDV ALLHLHGDSV GPGIGPCTQP NLAPSEAPGQ LGEKQVPSST SDDRVKDEFS
DLSEGDFLSE DENDKKQNPQ SSDESFEPYP EKKVSGKKSE SKDAKKPEEP KIRKKPGPKP
GWKKKLRSER EELPTIYKCP YQGCTAVYRG ADGMKKHIKE HHEEVRERPC PHPGCNKVFM
IDRYLQRHVK LIHTEVRNYI CDECGQTFKQ RKHLLVHQMR HSGAKPLQCE VCGFQCRQRA
SLKYHMTKHK AETELDFACD QCGRRFEKAH NLNVHMSMVH PLTQTQDRAL PLEAEPPPGP
LSLSGTMEGQ AVKPEPT
//
