ID A0A1U7QUF3_MESAU Unreviewed; 501 AA.
AC A0A1U7QUF3;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE RecName: Full=Centrosomal protein 57kDa-like protein 1 {ECO:0000256|ARBA:ARBA00041218};
DE AltName: Full=Cep57-related protein {ECO:0000256|ARBA:ARBA00042578};
GN Name=Cep57l1 {ECO:0000313|RefSeq:XP_005073285.2};
OS Mesocricetus auratus (Golden hamster).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea;
OC Cricetidae; Cricetinae; Mesocricetus.
OX NCBI_TaxID=10036 {ECO:0000313|Proteomes:UP000189706, ECO:0000313|RefSeq:XP_005073285.2};
RN [1] {ECO:0000313|RefSeq:XP_005073285.2}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, microtubule organizing
CC center, centrosome {ECO:0000256|ARBA:ARBA00004300}.
CC -!- SIMILARITY: Belongs to the translokin family.
CC {ECO:0000256|ARBA:ARBA00008179}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR RefSeq; XP_005073285.2; XM_005073228.3.
DR AlphaFoldDB; A0A1U7QUF3; -.
DR GeneID; 101827671; -.
DR KEGG; maua:101827671; -.
DR CTD; 285753; -.
DR eggNOG; ENOG502QTVF; Eukaryota.
DR OrthoDB; 5324077at2759; -.
DR Proteomes; UP000189706; Unplaced.
DR GO; GO:0005813; C:centrosome; IEA:UniProtKB-SubCell.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0005874; C:microtubule; IEA:UniProtKB-KW.
DR GO; GO:0043015; F:gamma-tubulin binding; IEA:InterPro.
DR GO; GO:0042802; F:identical protein binding; IEA:InterPro.
DR GO; GO:0008017; F:microtubule binding; IEA:InterPro.
DR Gene3D; 1.20.58.90; -; 1.
DR InterPro; IPR025913; Cep57_CLD.
DR InterPro; IPR024957; Cep57_MT-bd_dom.
DR PANTHER; PTHR19336:SF10; CENTROSOMAL PROTEIN CEP57L1; 1.
DR PANTHER; PTHR19336; UNCHARACTERIZED DUF1167; 1.
DR Pfam; PF14073; Cep57_CLD; 1.
DR Pfam; PF06657; Cep57_MT_bd; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Microtubule {ECO:0000256|ARBA:ARBA00022701};
KW Reference proteome {ECO:0000313|Proteomes:UP000189706}.
FT DOMAIN 95..272
FT /note="Cep57 centrosome localisation"
FT /evidence="ECO:0000259|Pfam:PF14073"
FT DOMAIN 355..425
FT /note="Cep57 centrosome microtubule-binding"
FT /evidence="ECO:0000259|Pfam:PF06657"
FT REGION 416..474
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 93..155
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 181..257
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 416..431
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 432..446
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 501 AA; 58357 MW; C42A44A4B795133E CRC64;
MLPTASVCDR NYNPHMPPQH LPLPANQRFW RPGFTENVHL TMDPELSHSV IGSYLNPPER
KYLPSFIQNE ASQNGHPVNS EVTPPKMFNS PNNRALVSAL KTLQEKIHRL ELERTQAEDN
LNSLCREAAQ YKKALENETN ERNLAHQELI KQKKDISIQL SSAQSRCTLL EKQLEYTKRM
VLNVEREKAM ILEQQAQLQR EKEQDQMKLH AKLEKLDVLE KECFRLTTTQ QTAEDKIKYL
EEKLKEEEHQ RKLFQDKACE LQTGLEISRI LMSTVSHSKL CKEKKKPLKK TKCLKREPPQ
QMDPKFRALS LEGGKMLHPY GLHYFQKPVL LPESRCLYKS LRTTSQDNAE PLNSGESISI
CDNLSELLMA MQEELDQMTM QHRELLKQMM QTRSHSDSDD IEHELEQLVK KMESKGDQIS
KLKKHQDSVR KLQQKVQNSR INASSGFLRE LGNPKGSKDT KNSPRKCLNE TNPFQKRVSF
RPVQAHNLQV KLRRDDIKWE Q
//
