ID A0A1U7QX26_MESAU Unreviewed; 580 AA.
AC A0A1U7QX26;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE SubName: Full=Tripartite motif-containing protein 45 {ECO:0000313|RefSeq:XP_005076572.1};
GN Name=Trim45 {ECO:0000313|RefSeq:XP_005076572.1};
OS Mesocricetus auratus (Golden hamster).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea;
OC Cricetidae; Cricetinae; Mesocricetus.
OX NCBI_TaxID=10036 {ECO:0000313|Proteomes:UP000189706, ECO:0000313|RefSeq:XP_005076572.1};
RN [1] {ECO:0000313|RefSeq:XP_005076572.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the TRIM/RBCC family.
CC {ECO:0000256|ARBA:ARBA00008518}.
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DR RefSeq; XP_005076572.1; XM_005076515.3.
DR AlphaFoldDB; A0A1U7QX26; -.
DR STRING; 10036.ENSMAUP00000013649; -.
DR GeneID; 101826539; -.
DR KEGG; maua:101826539; -.
DR CTD; 80263; -.
DR eggNOG; KOG2177; Eukaryota.
DR OrthoDB; 2916643at2759; -.
DR Proteomes; UP000189706; Unplaced.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd19809; Bbox1_TRIM45_C-X; 1.
DR CDD; cd19785; Bbox2_TRIM45_C-X; 1.
DR CDD; cd16588; RING-HC_TRIM45_C-VII; 1.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR003649; Bbox_C.
DR InterPro; IPR017868; Filamin/ABP280_repeat-like.
DR InterPro; IPR001298; Filamin/ABP280_rpt.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR014756; Ig_E-set.
DR InterPro; IPR047153; TRIM45/56/19.
DR InterPro; IPR000315; Znf_B-box.
DR InterPro; IPR018957; Znf_C3HC4_RING-type.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR InterPro; IPR017907; Znf_RING_CS.
DR PANTHER; PTHR25462; BONUS, ISOFORM C-RELATED; 1.
DR PANTHER; PTHR25462:SF291; TRIPARTITE MOTIF-CONTAINING PROTEIN 45; 1.
DR Pfam; PF00630; Filamin; 1.
DR Pfam; PF00643; zf-B_box; 1.
DR Pfam; PF00097; zf-C3HC4; 1.
DR SMART; SM00502; BBC; 1.
DR SMART; SM00336; BBOX; 2.
DR SMART; SM00557; IG_FLMN; 1.
DR SMART; SM00184; RING; 1.
DR SUPFAM; SSF57845; B-box zinc-binding domain; 1.
DR SUPFAM; SSF81296; E set domains; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR PROSITE; PS50194; FILAMIN_REPEAT; 1.
DR PROSITE; PS50119; ZF_BBOX; 2.
DR PROSITE; PS00518; ZF_RING_1; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000189706};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00024}.
FT DOMAIN 29..98
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT DOMAIN 130..176
FT /note="B box-type"
FT /evidence="ECO:0000259|PROSITE:PS50119"
FT DOMAIN 186..222
FT /note="B box-type"
FT /evidence="ECO:0000259|PROSITE:PS50119"
FT REPEAT 394..497
FT /note="Filamin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00087"
FT COILED 249..323
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 580 AA; 64029 MW; CF9E3C0F5E2C30C8 CRC64;
MSENRKPLLG FVHKVPDANA SGNSGKTHCP SCLGLFKAPR LLPCLHTVCT TCLEKLEPFS
VVDIRGGDSD TSSEGSIFQE PKSRSLQPQI GILCPVCDAQ VDLPLGGVKA LTIDHLAMND
VMLESLRGEG QGLVCDLCSD REVEKRCQTC KANLCHFCCQ AHRRQKKTMY HTMVDLKDLK
GYSRVGKPIL CPAHPAEELR LFCELCDRPV CRDCVVGEHR EHPYDFTSNV IHKHGDSVRE
LLRGTQPHVE ALEEALAQIK AMNSGLQERV EAVAADVRAF SEGYIKAIEE HRDKLLKQLD
DIRVQKENSL QLQKAQLEQL LADMRTGVEF TEHLLTSGSD LEILITKGVV VDRLRKLNKV
EYIARPGVND KICFSPQEKA GQCRGYEVYG TINTKEVDPA KCVLQGEDLH RAREKQPASF
TLLCKDAAGE NMGRGGDNVQ VAVVPKDKKD SPIRTVVQDN KDGSYHVSFT PKEAGVYTVW
VCIREQHVQG SPFTVTVRRK HRPHPGVFHC CTFCSSGGQK TARCACGGTM PGGYLGCGHG
HKGHPGRPHW SCCGKFIEKS ECTYTGGQSA PRSLLRTVAL
//
