ID A0A1U7QZR8_MESAU Unreviewed; 410 AA.
AC A0A1U7QZR8;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE RecName: Full=Transcription factor {ECO:0000256|PIRNR:PIRNR009404};
GN Name=Tfdp1 {ECO:0000313|RefSeq:XP_005082679.1,
GN ECO:0000313|RefSeq:XP_021090055.1, ECO:0000313|RefSeq:XP_021090056.1,
GN ECO:0000313|RefSeq:XP_021090057.1};
OS Mesocricetus auratus (Golden hamster).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea;
OC Cricetidae; Cricetinae; Mesocricetus.
OX NCBI_TaxID=10036 {ECO:0000313|Proteomes:UP000189706, ECO:0000313|RefSeq:XP_005082679.1};
RN [1] {ECO:0000313|RefSeq:XP_005082679.1, ECO:0000313|RefSeq:XP_021090055.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|PIRNR:PIRNR009404,
CC ECO:0000256|RuleBase:RU003796}.
CC -!- SIMILARITY: Belongs to the E2F/DP family.
CC {ECO:0000256|ARBA:ARBA00010940, ECO:0000256|PIRNR:PIRNR009404,
CC ECO:0000256|RuleBase:RU003796}.
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DR RefSeq; XP_005082679.1; XM_005082622.3.
DR RefSeq; XP_021090055.1; XM_021234396.1.
DR RefSeq; XP_021090056.1; XM_021234397.1.
DR RefSeq; XP_021090057.1; XM_021234398.1.
DR STRING; 10036.ENSMAUP00000009243; -.
DR GeneID; 101840311; -.
DR KEGG; maua:101840311; -.
DR CTD; 7027; -.
DR eggNOG; KOG2829; Eukaryota.
DR OrthoDB; 1343784at2759; -.
DR Proteomes; UP000189706; Unplaced.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0005667; C:transcription regulator complex; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0051726; P:regulation of cell cycle; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd14458; DP_DD; 1.
DR Gene3D; 1.20.140.80; Transcription factor DP; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR037241; E2F-DP_heterodim.
DR InterPro; IPR003316; E2F_WHTH_DNA-bd_dom.
DR InterPro; IPR038168; TF_DP_C_sf.
DR InterPro; IPR014889; Transc_factor_DP_C.
DR InterPro; IPR015648; Transcrpt_fac_DP.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR12548; TRANSCRIPTION FACTOR DP; 1.
DR PANTHER; PTHR12548:SF4; TRANSCRIPTION FACTOR DP-1; 1.
DR Pfam; PF08781; DP; 1.
DR Pfam; PF02319; E2F_TDP; 1.
DR PIRSF; PIRSF009404; Transcription_factor_DP; 1.
DR SMART; SM01138; DP; 1.
DR SMART; SM01372; E2F_TDP; 1.
DR SUPFAM; SSF144074; E2F-DP heterodimerization region; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|PIRNR:PIRNR009404, ECO:0000256|RuleBase:RU003796};
KW Nucleus {ECO:0000256|PIRNR:PIRNR009404, ECO:0000256|RuleBase:RU003796};
KW Reference proteome {ECO:0000313|Proteomes:UP000189706};
KW Transcription {ECO:0000256|PIRNR:PIRNR009404,
KW ECO:0000256|RuleBase:RU003796};
KW Transcription regulation {ECO:0000256|PIRNR:PIRNR009404,
KW ECO:0000256|RuleBase:RU003796}.
FT DOMAIN 111..193
FT /note="E2F/DP family winged-helix DNA-binding"
FT /evidence="ECO:0000259|SMART:SM01372"
FT DOMAIN 200..344
FT /note="Transcription factor DP C-terminal"
FT /evidence="ECO:0000259|SMART:SM01138"
FT REGION 77..114
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 370..410
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 77..102
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 370..387
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 393..410
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 410 AA; 45200 MW; 7A891F44EE67BBB7 CRC64;
MAKDASLIEA NGELKVFIDQ NLSPGKGVVS LVAVHPSTVS TLGKQLLPKT FGQSNVNITQ
QVVIGTPQRP AASNTIVVGS PHTPNTHFVS QNQPSDSSPW SAGKRNRKGE KNGKGLRHFS
MKVCEKVQRK GTTSYNEVAD ELVAEFSAAD NHILPNESAY DQKNIRRRVY DALNVLMAMN
IISKEKKEIK WIGLPTNSAQ ECQNLEVERQ RRLERIKQKQ SQLQELILQQ IAFKNLVQRN
RQAEQQARRP PPPNSVIHLP FIIVNTSRKT VIDCSISNDK FEYLFNFDNT FEIHDDIEVL
KRMGMACGLE SGNCSAEDLK VARSLVPKAL EPYVTEMAQG SIGGVFVTTT GSTSNGTRLS
ASDLSNGADG MLATSSNGSQ YSGSRVETPV SYVGEDDDDD DDFNENDEED
//
