ID A0A1U7R0P3_ALLSI Unreviewed; 282 AA.
AC A0A1U7R0P3;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE RecName: Full=GPN-loop GTPase 3 {ECO:0000256|ARBA:ARBA00014587, ECO:0000256|RuleBase:RU365059};
GN Name=GPN3 {ECO:0000313|RefSeq:XP_006015275.1};
OS Alligator sinensis (Chinese alligator).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Crocodylia; Alligatoridae; Alligatorinae;
OC Alligator.
OX NCBI_TaxID=38654 {ECO:0000313|Proteomes:UP000189705, ECO:0000313|RefSeq:XP_006015275.1};
RN [1] {ECO:0000313|RefSeq:XP_006015275.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- FUNCTION: Small GTPase required for proper localization of RNA
CC polymerase II (RNAPII). May act at an RNAP assembly step prior to
CC nuclear import. {ECO:0000256|ARBA:ARBA00002411}.
CC -!- FUNCTION: Small GTPase required for proper nuclear import of RNA
CC polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly
CC step prior to nuclear import. {ECO:0000256|RuleBase:RU365059}.
CC -!- SUBUNIT: Binds to RNA polymerase II (RNAPII).
CC {ECO:0000256|RuleBase:RU365059}.
CC -!- SIMILARITY: Belongs to the GPN-loop GTPase family.
CC {ECO:0000256|ARBA:ARBA00005290, ECO:0000256|RuleBase:RU365059}.
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DR RefSeq; XP_006015275.1; XM_006015213.3.
DR STRING; 38654.A0A1U7R0P3; -.
DR GeneID; 102383162; -.
DR KEGG; asn:102383162; -.
DR CTD; 51184; -.
DR eggNOG; KOG1534; Eukaryota.
DR InParanoid; A0A1U7R0P3; -.
DR OrthoDB; 168004at2759; -.
DR Proteomes; UP000189705; Unplaced.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR CDD; cd17872; GPN3; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR004130; Gpn.
DR InterPro; IPR030228; Gpn3.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR21231:SF7; GPN-LOOP GTPASE 3; 1.
DR PANTHER; PTHR21231; XPA-BINDING PROTEIN 1-RELATED; 1.
DR Pfam; PF03029; ATP_bind_1; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW GTP-binding {ECO:0000256|RuleBase:RU365059};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU365059};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|RuleBase:RU365059};
KW Reference proteome {ECO:0000313|Proteomes:UP000189705}.
SQ SEQUENCE 282 AA; 32619 MW; 47524B9E6287EB44 CRC64;
MPRYAQLVMG PAGSGKSTYC STMVQHCEAL NRXXXXXXXX XEYFNYPVMA DIRELIEVDD
VMEDDSLRFG PNGGLVFCME YFANNFDWLE ESLGHVEDDY ILFDCPGQIE LYTHLPVMKQ
LVEQLQQWEF RVCGVFLVDS QFMVESFKFI SGVLAALSAM ISLEIPQVNI MTKMDLLSKK
AKKEIEKYLD PDMYPLIEDS TNILKSKMFK KLTTAICGLI DDYSMVRFLP YDRSDEESIN
IVLQHIDFTI QYGEDLEFKE PKDCEEVKSS LVDEYFQDQV DE
//
