ID A0A1U7R421_MESAU Unreviewed; 955 AA.
AC A0A1U7R421;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE SubName: Full=Squamous cell carcinoma antigen recognized by T-cells 3 isoform X2 {ECO:0000313|RefSeq:XP_005078984.1};
GN Name=Sart3 {ECO:0000313|RefSeq:XP_005078984.1};
OS Mesocricetus auratus (Golden hamster).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea;
OC Cricetidae; Cricetinae; Mesocricetus.
OX NCBI_TaxID=10036 {ECO:0000313|Proteomes:UP000189706, ECO:0000313|RefSeq:XP_005078984.1};
RN [1] {ECO:0000313|RefSeq:XP_005078984.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_005078984.1; XM_005078927.3.
DR AlphaFoldDB; A0A1U7R421; -.
DR STRING; 10036.ENSMAUP00000012018; -.
DR GeneID; 101844583; -.
DR KEGG; maua:101844583; -.
DR CTD; 9733; -.
DR eggNOG; KOG0128; Eukaryota.
DR OrthoDB; 2879516at2759; -.
DR Proteomes; UP000189706; Unplaced.
DR GO; GO:0015030; C:Cajal body; IEA:Ensembl.
DR GO; GO:0071001; C:U4/U6 snRNP; IEA:Ensembl.
DR GO; GO:0005691; C:U6atac snRNP; IEA:Ensembl.
DR GO; GO:0042393; F:histone binding; IEA:Ensembl.
DR GO; GO:0030621; F:U4 snRNA binding; IEA:Ensembl.
DR GO; GO:0017070; F:U6 snRNA binding; IEA:Ensembl.
DR GO; GO:0030624; F:U6atac snRNA binding; IEA:Ensembl.
DR GO; GO:1990381; F:ubiquitin-specific protease binding; IEA:Ensembl.
DR GO; GO:0000902; P:cell morphogenesis; IEA:Ensembl.
DR GO; GO:0071425; P:hematopoietic stem cell proliferation; IEA:Ensembl.
DR GO; GO:0048872; P:homeostasis of number of cells; IEA:Ensembl.
DR GO; GO:0006334; P:nucleosome assembly; IEA:Ensembl.
DR GO; GO:0010468; P:regulation of gene expression; IEA:Ensembl.
DR GO; GO:0000244; P:spliceosomal tri-snRNP complex assembly; IEA:Ensembl.
DR GO; GO:0140673; P:transcription elongation-coupled chromatin remodeling; IEA:Ensembl.
DR CDD; cd12391; RRM1_SART3; 1.
DR CDD; cd12392; RRM2_SART3; 1.
DR Gene3D; 3.30.70.330; -; 2.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 2.
DR InterPro; IPR003107; HAT.
DR InterPro; IPR008669; LSM_interact.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR000504; RRM_dom.
DR InterPro; IPR034217; SART3_RRM1.
DR InterPro; IPR034218; SART3_RRM2.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR PANTHER; PTHR15481; RIBONUCLEIC ACID BINDING PROTEIN S1; 1.
DR PANTHER; PTHR15481:SF5; SQUAMOUS CELL CARCINOMA ANTIGEN RECOGNIZED BY T-CELLS 3; 1.
DR Pfam; PF16605; LSM_int_assoc; 1.
DR Pfam; PF05391; Lsm_interact; 1.
DR Pfam; PF00076; RRM_1; 2.
DR SMART; SM00386; HAT; 7.
DR SMART; SM00360; RRM; 2.
DR SUPFAM; SSF54928; RNA-binding domain, RBD; 2.
DR SUPFAM; SSF48452; TPR-like; 1.
DR PROSITE; PS50102; RRM; 2.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000189706};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|PROSITE-
KW ProRule:PRU00176}.
FT DOMAIN 697..775
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT DOMAIN 794..871
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT REGION 1..94
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 589..656
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 914..938
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 79..94
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 589..604
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 955 AA; 109042 MW; D159BF861CEEAD82 CRC64;
MATAAASSAS EPEVEPQAGP EAEGEEDEAK AASVDRKVLS RAVAADAAKG PGWDLQREGV
SESDGDEEDA MASSAESSPG EDEWEDEEEE EKNQLEIERL EEQLSINGYD YNCHVELIRL
LRLEGELNKV RMARQKMSEL FPLTEELWLE WLHDEISMAM DGLDREHVYE LFERAVKDYI
CPNIWLEYGQ YSVGGIGQKG GLEKVRSVFE RALSSVGLHV TKGLAIWEAY REFESAIVEA
ARLEKVHSLF RRQLAIPLYD MEATLAEYEE WSEDPIPESV LQSYQKALEQ LEKYKPYEEA
LLQAEAPRLA EYQAYIDFEM KIGDPARIQL IFERALVENC LVPDLWIRYS RYLDRQLKVK
DLVLSVHSRA VRNCPWTVAL WSRYLLAMER HGVDHQMISA TFENALSAGF IQATDYVEIW
QVYLDYLRRR VDFKQDSSKE LEELRSMFTR ALEYLQQEVE ERFNESGDPS CVIMQSWARV
EARLCNNMQK ARELWDSIMT RGNAKYANMW LEYYNLERAH GDTQHCRKAL HRAVQCTSDY
PEHVCEVLLT MERTEGTLED WDVAIQKTET RLARVNEQRM KAAEKEAALV QQEEERAEQR
KKVRAEKKAL KKKKKTHGAE KRKVDEEDEE EEEQPSKRRR VENSLASGVA STMQEDTELS
GKCVTIDVAS PSKQKEKAAS LKLDMPKVAH DSSKDRVTVF VSNLPYSMDE PEVKLRPLFE
ACGEVVQIRP VFSNRGDFRG YCYVEFKEEK SAQQALELDR KNVEGRPMFV SPCVDKSKNP
DFKVFRYSTT LEKHKLFISG LPFSCTKEEL EDICKAHGTV KDLRLVTNRA GKPKGLAYVE
YESESQASQA VMKMDGMTIK ENVIKVAISN PPQRKVPEKL EVRTAPGAPM LPRQMYGARG
KGRTQLSLLP RALQRHSAAP QAENGPAVGP AVTTSMATEA PKMSNADFAK LLLRK
//
