ID A0A1U7R6V1_ALLSI Unreviewed; 138 AA.
AC A0A1U7R6V1;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Calcitonin {ECO:0000313|RefSeq:XP_006018294.1};
GN Name=CALCA {ECO:0000313|RefSeq:XP_006018294.1};
OS Alligator sinensis (Chinese alligator).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Crocodylia; Alligatoridae; Alligatorinae;
OC Alligator.
OX NCBI_TaxID=38654 {ECO:0000313|Proteomes:UP000189705, ECO:0000313|RefSeq:XP_006018294.1};
RN [1] {ECO:0000313|RefSeq:XP_006018294.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
CC -!- SIMILARITY: Belongs to the calcitonin family.
CC {ECO:0000256|ARBA:ARBA00009222}.
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DR RefSeq; XP_006018294.1; XM_006018232.3.
DR AlphaFoldDB; A0A1U7R6V1; -.
DR STRING; 38654.A0A1U7R6V1; -.
DR GeneID; 102369022; -.
DR KEGG; asn:102369022; -.
DR CTD; 796; -.
DR eggNOG; ENOG502RZI5; Eukaryota.
DR InParanoid; A0A1U7R6V1; -.
DR OrthoDB; 4002581at2759; -.
DR Proteomes; UP000189705; Unplaced.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0005179; F:hormone activity; IEA:InterPro.
DR InterPro; IPR021118; Calcitonin.
DR InterPro; IPR021117; Calcitonin-like.
DR InterPro; IPR021116; Calcitonin/adrenomedullin.
DR InterPro; IPR018360; Calcitonin_CS.
DR InterPro; IPR001693; Calcitonin_peptide-like.
DR PANTHER; PTHR10505:SF16; CALCITONIN; 1.
DR PANTHER; PTHR10505; CALCITONIN-RELATED; 1.
DR Pfam; PF00214; Calc_CGRP_IAPP; 1.
DR PRINTS; PR00270; CALCITONINA.
DR SMART; SM00113; CALCITONIN; 1.
DR PROSITE; PS00258; CALCITONIN; 1.
PE 3: Inferred from homology;
KW Cleavage on pair of basic residues {ECO:0000256|ARBA:ARBA00022685};
KW Disulfide bond {ECO:0000256|PIRSR:PIRSR621116-50};
KW Reference proteome {ECO:0000313|Proteomes:UP000189705};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..25
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 26..138
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5010583027"
FT DOMAIN 80..117
FT /note="Calcitonin peptide-like"
FT /evidence="ECO:0000259|SMART:SM00113"
FT DISULFID 82..88
FT /evidence="ECO:0000256|PIRSR:PIRSR621116-50"
SQ SEQUENCE 138 AA; 15360 MW; ECD1A10E191BD1CE CRC64;
MVMLKISSFL AVYALVVCQM DSFQAAPLRP GLESMTDRVT LSDYEARRLL NALVKEFIQM
TAEDLEKVTE GNSLDRPISK RCASLSTCVL GKLSQELHKL QTYPRTDVGA GTPGKKRNVL
NDLENERYAN YGESLGNN
//
