ID A0A1U7R7I0_ALLSI Unreviewed; 431 AA.
AC A0A1U7R7I0;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE SubName: Full=Forkhead box protein N2 {ECO:0000313|RefSeq:XP_006014785.1, ECO:0000313|RefSeq:XP_025058619.1};
GN Name=FOXN2 {ECO:0000313|RefSeq:XP_006014785.1,
GN ECO:0000313|RefSeq:XP_025058619.1};
OS Alligator sinensis (Chinese alligator).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Crocodylia; Alligatoridae; Alligatorinae;
OC Alligator.
OX NCBI_TaxID=38654 {ECO:0000313|Proteomes:UP000189705, ECO:0000313|RefSeq:XP_006014785.1};
RN [1] {ECO:0000313|RefSeq:XP_006014785.1, ECO:0000313|RefSeq:XP_025058619.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|PROSITE-ProRule:PRU00089}.
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DR RefSeq; XP_006014785.1; XM_006014723.3.
DR RefSeq; XP_025058619.1; XM_025202834.1.
DR STRING; 38654.A0A1U7R7I0; -.
DR GeneID; 102387390; -.
DR KEGG; asn:102387390; -.
DR CTD; 3344; -.
DR eggNOG; KOG2294; Eukaryota.
DR OrthoDB; 5385885at2759; -.
DR Proteomes; UP000189705; Unplaced.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR CDD; cd20058; FH_FOXN2; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR047403; FH_FOXN2.
DR InterPro; IPR001766; Fork_head_dom.
DR InterPro; IPR047119; FOXN2/3-like.
DR InterPro; IPR018122; TF_fork_head_CS_1.
DR InterPro; IPR030456; TF_fork_head_CS_2.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR13962:SF19; FORKHEAD BOX PROTEIN N2; 1.
DR PANTHER; PTHR13962; FORKHEAD BOX PROTEIN N3-LIKE PROTEIN-RELATED; 1.
DR Pfam; PF00250; Forkhead; 1.
DR PRINTS; PR00053; FORKHEAD.
DR SMART; SM00339; FH; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS00657; FORK_HEAD_1; 1.
DR PROSITE; PS00658; FORK_HEAD_2; 1.
DR PROSITE; PS50039; FORK_HEAD_3; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU00089}; Nucleus {ECO:0000256|PROSITE-ProRule:PRU00089};
KW Reference proteome {ECO:0000313|Proteomes:UP000189705}.
FT DOMAIN 112..199
FT /note="Fork-head"
FT /evidence="ECO:0000259|PROSITE:PS50039"
FT DNA_BIND 112..199
FT /note="Fork-head"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00089"
FT REGION 1..21
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 275..314
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 281..314
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 431 AA; 47086 MW; 61375DA0289D9EA5 CRC64;
MGPVTGMTPD KKAETPGAGK AAGLRQIYRM GSLPEAVDAA PPKATLVDSE SADDELTNLN
WLHESTNLLT NFSLGSEGLP MVSPLYDIEG DNVPSFSPSC YQNMEKKSAT SKPPYSFSLL
IYMAIEHSPN KSLPVKEIYS WILERFPYFA TAPTGWKNSV RHNLSLNKCF RKVERSHGKV
NGKGSLWCVD PEYKPNLIQA LKKQPFPSAL AFYTPPASPP SRPSSPHYLT SVLKQNHGRS
LKESDIDAAT AMMLLNTSIE QGMLDCEKPQ PLKTAKKRSY GSAFNPHSSV NLQENDSAAT
NIDPKKDHNY SVSSVASQRC ASRSSVSSLS SVDEVYEFIS KTSHAGSDSS EGFHSEVDTD
VDYEDDPLGD SGYASQPCVN TSDRVFKELC QEIDEELKEA AGSLLHLAGI HTCLGSLIST
AKAHSQKQRK K
//
