ID A0A1U7R8I7_ALLSI Unreviewed; 1114 AA.
AC A0A1U7R8I7;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=Transient receptor potential cation channel subfamily A member 1 {ECO:0000313|RefSeq:XP_006015374.1};
GN Name=TRPA1 {ECO:0000313|RefSeq:XP_006015374.1};
OS Alligator sinensis (Chinese alligator).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Crocodylia; Alligatoridae; Alligatorinae;
OC Alligator.
OX NCBI_TaxID=38654 {ECO:0000313|Proteomes:UP000189705, ECO:0000313|RefSeq:XP_006015374.1};
RN [1] {ECO:0000313|RefSeq:XP_006015374.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_006015374.1; XM_006015312.1.
DR AlphaFoldDB; A0A1U7R8I7; -.
DR STRING; 38654.A0A1U7R8I7; -.
DR GeneID; 102367987; -.
DR KEGG; asn:102367987; -.
DR CTD; 8989; -.
DR eggNOG; KOG0510; Eukaryota.
DR InParanoid; A0A1U7R8I7; -.
DR OrthoDB; 2910129at2759; -.
DR Proteomes; UP000189705; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005216; F:monoatomic ion channel activity; IEA:InterPro.
DR GO; GO:0050896; P:response to stimulus; IEA:UniProtKB-KW.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 3.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR005821; Ion_trans_dom.
DR PANTHER; PTHR47143; TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL PROTEIN PAINLESS; 1.
DR PANTHER; PTHR47143:SF3; TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL PROTEIN PAINLESS; 1.
DR Pfam; PF12796; Ank_2; 6.
DR Pfam; PF00520; Ion_trans; 1.
DR PRINTS; PR01415; ANKYRIN.
DR SMART; SM00248; ANK; 14.
DR SUPFAM; SSF48403; Ankyrin repeat; 2.
DR PROSITE; PS50297; ANK_REP_REGION; 6.
DR PROSITE; PS50088; ANK_REPEAT; 9.
PE 4: Predicted;
KW ANK repeat {ECO:0000256|ARBA:ARBA00023043, ECO:0000256|PROSITE-
KW ProRule:PRU00023};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Receptor {ECO:0000313|RefSeq:XP_006015374.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000189705};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Sensory transduction {ECO:0000256|ARBA:ARBA00022606};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 725..745
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 768..786
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 830..850
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 870..892
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 935..961
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REPEAT 102..134
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 169..201
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 243..275
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 313..345
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 346..378
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 417..449
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 450..482
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 486..511
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 552..584
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT DOMAIN 775..970
FT /note="Ion transport"
FT /evidence="ECO:0000259|Pfam:PF00520"
SQ SEQUENCE 1114 AA; 125643 MW; 485EED3C7475B093 CRC64;
MRRSLLKLFQ GREKAADPDT YHGVVCEADA ASVASQDVFK VISDGSTCRL RSFIKKNRSG
LSKVDELHAT PLHHAAEGGQ IELMQMIIDD SSYEVLNVTD SSGNTPLHWA TKKNQIESVK
LLLRKGANPN ILNSNMMAPL HMSVQSLQNE IVKILVQHSS TDVNLEGEAG NTPIIVACYK
DNPEALTLLI ENGGKICKPN KTGCMPIHAA AFSGAKTCME ILLKKGEELG YSAKTHINFT
NNGKCSPLHL AVQSGDLEMI RMCIEVGAQI DLKQNEKCTA LHFAATQGAT EIVKLMMSSY
AGDESLIDAV DGNKETLLHR TALFDHYELA EYLLSMGANI NSIDTEGRSP LLLATSCASW
KIVNLLLSKG ANVSLKDQLG RNFLHLTVLQ PGGLQHLNET FLQMKHIKEL VVDEDNEGCT
PLHYACRQGV ALSVNKLLNL NVSIYSKSRD KKSPLHFAAS YGRINTCQRL LRDMEDTRLL
NEGDRKGMTP LHLASQNGHE KVVQLLLKKG ALFLCDYKGW TALHHAAFGG FTRTMQIILD
TNAKCTDKVD EEGNTALHLA AREGHPKAVK LLLDHGAKIL LNKAVASFFH EAIHSRQKDV
VSVIILNKRW EEAVTTFSHS CSANKCPLLE MVEYLPESFK LVLDNCMSES SEEKTNRDFY
IEYNFRYLQC PLTLRKPKGD EEIEYEPLTI LNAMVRHNCM ELLSHPVCKE YLLMKWMAYG
FRAHLMNLGV YSLGLIPLTL LVTNIKPRKT LNGSETYNSG PLVSEESYFI RVCMCLVLIM
SLLGICKEIF QLIQQKLKYL LDYSNLLDWT IYTTSIIFVS SLFATIPGHL QWECGAIAVY
LSWMNFLLYL QRFENYGIYV VMFWEILRTL IRIVVVFFFL ILAFGLSFFV LLGSQKTYSS
PLLSVMKTFA MMLGDINYHD AFLGPLLSNE LPYPFLSYTV LIIFTLLIPI LLMNLLIGLA
VGDIAEVQKY AALKRIAMQV NLHTNLEKKL PYWFLSRVDQ ESITVYPNRP RYCGFMSVFQ
YCFGCEDNTT DTHSTDSTLE LEVLKQKYRL KDISTLLERQ HDLIKLILQK MEIVSEAEDE
DSNDLFQQNF RKQQLENRNS KWDTVLKVVK SKGA
//
