ID A0A1U7RCI4_MESAU Unreviewed; 1254 AA.
AC A0A1U7RCI4;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=Cell adhesion molecule-related/down-regulated by oncogenes isoform X1 {ECO:0000313|RefSeq:XP_005085899.1};
GN Name=Cdon {ECO:0000313|RefSeq:XP_005085899.1};
OS Mesocricetus auratus (Golden hamster).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea;
OC Cricetidae; Cricetinae; Mesocricetus.
OX NCBI_TaxID=10036 {ECO:0000313|Proteomes:UP000189706, ECO:0000313|RefSeq:XP_005085899.1};
RN [1] {ECO:0000313|RefSeq:XP_005085899.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_005085899.1; XM_005085842.3.
DR AlphaFoldDB; A0A1U7RCI4; -.
DR STRING; 10036.ENSMAUP00000021804; -.
DR GeneID; 101841139; -.
DR KEGG; maua:101841139; -.
DR CTD; 50937; -.
DR eggNOG; ENOG502QT4P; Eukaryota.
DR OrthoDB; 3138076at2759; -.
DR Proteomes; UP000189706; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0009952; P:anterior/posterior pattern specification; IEA:Ensembl.
DR GO; GO:0001708; P:cell fate specification; IEA:Ensembl.
DR GO; GO:0021987; P:cerebral cortex development; IEA:Ensembl.
DR GO; GO:0010172; P:embryonic body morphogenesis; IEA:Ensembl.
DR GO; GO:0060059; P:embryonic retina morphogenesis in camera-type eye; IEA:Ensembl.
DR GO; GO:0002088; P:lens development in camera-type eye; IEA:Ensembl.
DR GO; GO:0007520; P:myoblast fusion; IEA:Ensembl.
DR GO; GO:0007405; P:neuroblast proliferation; IEA:Ensembl.
DR GO; GO:0030182; P:neuron differentiation; IEA:Ensembl.
DR GO; GO:0043410; P:positive regulation of MAPK cascade; IEA:Ensembl.
DR GO; GO:0002052; P:positive regulation of neuroblast proliferation; IEA:Ensembl.
DR GO; GO:0045666; P:positive regulation of neuron differentiation; IEA:Ensembl.
DR GO; GO:0001934; P:positive regulation of protein phosphorylation; IEA:Ensembl.
DR GO; GO:0048643; P:positive regulation of skeletal muscle tissue development; IEA:Ensembl.
DR GO; GO:0051057; P:positive regulation of small GTPase mediated signal transduction; IEA:Ensembl.
DR GO; GO:0045944; P:positive regulation of transcription by RNA polymerase II; IEA:Ensembl.
DR GO; GO:0014816; P:skeletal muscle satellite cell differentiation; IEA:Ensembl.
DR GO; GO:0007224; P:smoothened signaling pathway; IEA:Ensembl.
DR CDD; cd00063; FN3; 3.
DR CDD; cd00096; Ig; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 8.
DR InterPro; IPR003961; FN3_dom.
DR InterPro; IPR036116; FN3_sf.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR013098; Ig_I-set.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR PANTHER; PTHR44170:SF30; FIBRONECTIN TYPE-III DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR44170; PROTEIN SIDEKICK; 1.
DR Pfam; PF00041; fn3; 3.
DR Pfam; PF07679; I-set; 1.
DR Pfam; PF13927; Ig_3; 3.
DR SMART; SM00060; FN3; 3.
DR SMART; SM00409; IG; 5.
DR SMART; SM00408; IGc2; 5.
DR SUPFAM; SSF49265; Fibronectin type III; 2.
DR SUPFAM; SSF48726; Immunoglobulin; 5.
DR PROSITE; PS50853; FN3; 3.
DR PROSITE; PS50835; IG_LIKE; 5.
PE 4: Predicted;
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Immunoglobulin domain {ECO:0000256|ARBA:ARBA00023319};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000189706};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}; Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..24
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 25..1254
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5010544373"
FT TRANSMEM 960..985
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 28..113
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 138..203
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 224..302
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 309..395
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 404..515
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 572..673
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 719..814
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 822..922
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT REGION 524..545
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 670..689
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 928..951
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1166..1212
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 670..684
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 935..951
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1170..1193
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1194..1210
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1254 AA; 136302 MW; DBDDBECFF75FFB26 CRC64;
MHPDLGPLWT LLYVLGILCS SVSSDLVPYF ISEPLSAVQK LGRPVDLHCS AKPVTARISW
LHNGKRLDSN MEQIKIHQGT LTILSLNPSL SGYYQCVANN SIGAIVSGPA TVSTAALGDF
DSSTMHVITA EEKNTGFIGC RVPESNPKAE VRYKIRGKWL KYSTGNYIIL PSGNLQILNV
SSKDKGSYKC AAYNPVTNEL KVEPTGRKLL VSRPSSDGFH ILHPALSQAL AVLPHSPVTL
ECVVSGVPAS QVYWLKDGQD AVSGSNWRRV HSHLATASID SADSGNYSCV VGNRSGDVKH
VTYMVNVLER ASISKGLQDQ KVSLGATVHF TCDVHGNPAP NRTWFHNAQP IHPSSRHLTE
GNGLKITGVT MEDSGLYQCV ADNGIGLMQS TGRLQIEQDS GLKPVIVTAP ENVEVMDGDF
VTLSCNATGV PVPTIHWYGH RGLITSHPSQ VLRSKSRKSH LLRHRDLDLE PVYFIMSRAG
SSSLSIRAAT QEHAGKYTCE ATNKHGATQS EAFLTVVPFE TNTKAESVTP SEATQNDERD
PRDGLESSLL SLFPVKVHSS GVELPTQKNA SVPDAPHILS PPQTHMPDTY NLVWRAGRDG
GLPINAYFVK YRKLDDGTGT VGSWHTVRVP GSENELHLTE LEPSSLYEVL MVARSTVGEG
QPAMLTFRTS KEKMASSKNT QASFPPVGIP KRPVISEASN SNFGVVLTDS SRHSGVPEAP
DRPTISTASE TSVYVTWIPR ANGGSPITAF KVEYKRMRSS DWLVAAEDIP PSKLSVEVRS
LEPGSTYKFR VIAINHYGES FRSSASRPYQ VAGFPNRFSN RPITGPHIAY TEAVSDTQIM
LKWTYIPSSN NNTPIQGFYI YYRPTDSDND SDYKRDVVEG SKQWHTIGHL QPETSYDIKM
QCFNEGGESE FSNVMICETK VKRVPGASEY PVKDLSTPPG SSGNGGNVGP ATSPARSSDM
LYLIVGCVLG VMVLILMVFI ALCLWKSRQQ NAIQKYDPPG YLYQGSEMNG QMVEYTTLSG
TTRINGSVHG GFLSKGSLGN GCSHLHHKVP NGVNGVLNGS INGGLYSAHT NSLTRTCVEF
EHPRHLMNGG GMYTAVPQID PLECINCRNC RNNNRCFTKT NSPLPVVPVL ASYPQDGLEM
KPLSALKVPV CPASTLPDCG QLPEESLKDS VAPTPTQHTC CQDNISDINS DSTEDTAEFS
RGDRNGHSEA EDNVLSWNPH ILSPVLEDCP EKTAWSPGLP LDGLSVVLQQ AQET
//
