ID A0A1U7REJ0_ALLSI Unreviewed; 273 AA.
AC A0A1U7REJ0;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=SPRY domain-containing SOCS box protein 4 isoform X1 {ECO:0000313|RefSeq:XP_006016591.1};
GN Name=SPSB4 {ECO:0000313|RefSeq:XP_006016591.1};
OS Alligator sinensis (Chinese alligator).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Crocodylia; Alligatoridae; Alligatorinae;
OC Alligator.
OX NCBI_TaxID=38654 {ECO:0000313|Proteomes:UP000189705, ECO:0000313|RefSeq:XP_006016591.1};
RN [1] {ECO:0000313|RefSeq:XP_006016591.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- PATHWAY: Protein modification; protein ubiquitination.
CC {ECO:0000256|ARBA:ARBA00004906}.
CC -!- SIMILARITY: Belongs to the SPSB family.
CC {ECO:0000256|ARBA:ARBA00010910}.
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DR RefSeq; XP_006016591.1; XM_006016529.3.
DR AlphaFoldDB; A0A1U7REJ0; -.
DR STRING; 38654.A0A1U7REJ0; -.
DR GeneID; 102379738; -.
DR KEGG; asn:102379738; -.
DR CTD; 92369; -.
DR eggNOG; KOG3953; Eukaryota.
DR InParanoid; A0A1U7REJ0; -.
DR OrthoDB; 65989at2759; -.
DR UniPathway; UPA00143; -.
DR Proteomes; UP000189705; Unplaced.
DR GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR CDD; cd03743; SOCS_SSB4; 1.
DR CDD; cd12906; SPRY_SOCS1-2-4; 1.
DR Gene3D; 2.60.120.920; -; 1.
DR Gene3D; 1.10.750.20; SOCS box; 1.
DR InterPro; IPR001870; B30.2/SPRY.
DR InterPro; IPR043136; B30.2/SPRY_sf.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR001496; SOCS_box.
DR InterPro; IPR036036; SOCS_box-like_dom_sf.
DR InterPro; IPR003877; SPRY_dom.
DR PANTHER; PTHR12245; SPRY DOMAIN CONTAINING SOCS BOX PROTEIN; 1.
DR PANTHER; PTHR12245:SF3; SPRY DOMAIN-CONTAINING SOCS BOX PROTEIN 4; 1.
DR Pfam; PF07525; SOCS_box; 1.
DR Pfam; PF00622; SPRY; 1.
DR SMART; SM00969; SOCS_box; 1.
DR SMART; SM00449; SPRY; 1.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR SUPFAM; SSF158235; SOCS box-like; 1.
DR PROSITE; PS50188; B302_SPRY; 1.
DR PROSITE; PS50225; SOCS; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000189705}.
FT DOMAIN 34..231
FT /note="B30.2/SPRY"
FT /evidence="ECO:0000259|PROSITE:PS50188"
FT DOMAIN 221..273
FT /note="SOCS box"
FT /evidence="ECO:0000259|PROSITE:PS50225"
SQ SEQUENCE 273 AA; 31122 MW; E771C65B994E181F CRC64;
MGQKISGSIK SVDVREPPYR PVKRELRGPD FCKPARLDML LDMPPAKLEV QYKHAWNNED
RSLNIFVKED DKLTFHRHPV AQSTDCIRGK VGYTRGLHVW QIHWPTRQRG THAVVGVSTA
EAPLHSVGYT SLVGSNSESW GWDLGRNKLY HNCKNQPGVT YPVFLEPDEP FVLPDTLLVV
LDMDEGTLSF MVDGQYLGVA FRGLKGKKVY PIVSAVWGHC EITMRYINGL DPEPLPLMDL
CRRSIRFALG RDRLHDIESL PLPQSLKNYL QYQ
//
