ID A0A1U7REV6_MESAU Unreviewed; 465 AA.
AC A0A1U7REV6;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=Ankyrin repeat and SOCS box protein 10 isoform X2 {ECO:0000313|RefSeq:XP_005087295.1};
GN Name=Asb10 {ECO:0000313|RefSeq:XP_005087295.1};
OS Mesocricetus auratus (Golden hamster).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea;
OC Cricetidae; Cricetinae; Mesocricetus.
OX NCBI_TaxID=10036 {ECO:0000313|Proteomes:UP000189706, ECO:0000313|RefSeq:XP_005087295.1};
RN [1] {ECO:0000313|RefSeq:XP_005087295.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- PATHWAY: Protein modification; protein ubiquitination.
CC {ECO:0000256|ARBA:ARBA00004906}.
CC -!- SIMILARITY: Belongs to the ankyrin SOCS box (ASB) family.
CC {ECO:0000256|ARBA:ARBA00005949}.
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DR RefSeq; XP_005087295.1; XM_005087238.3.
DR AlphaFoldDB; A0A1U7REV6; -.
DR STRING; 10036.ENSMAUP00000014537; -.
DR GeneID; 101834695; -.
DR KEGG; maua:101834695; -.
DR CTD; 136371; -.
DR eggNOG; KOG0504; Eukaryota.
DR OrthoDB; 1787271at2759; -.
DR UniPathway; UPA00143; -.
DR Proteomes; UP000189706; Unplaced.
DR GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 3.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR001496; SOCS_box.
DR InterPro; IPR036036; SOCS_box-like_dom_sf.
DR PANTHER; PTHR24126:SF14; 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 10-RELATED; 1.
DR PANTHER; PTHR24126; ANKYRIN REPEAT, PH AND SEC7 DOMAIN CONTAINING PROTEIN SECG-RELATED; 1.
DR Pfam; PF00023; Ank; 1.
DR Pfam; PF12796; Ank_2; 2.
DR Pfam; PF07525; SOCS_box; 1.
DR PRINTS; PR01415; ANKYRIN.
DR SMART; SM00248; ANK; 7.
DR SMART; SM00969; SOCS_box; 1.
DR SUPFAM; SSF48403; Ankyrin repeat; 1.
DR SUPFAM; SSF158235; SOCS box-like; 1.
DR PROSITE; PS50297; ANK_REP_REGION; 5.
DR PROSITE; PS50088; ANK_REPEAT; 5.
DR PROSITE; PS50225; SOCS; 1.
PE 3: Inferred from homology;
KW ANK repeat {ECO:0000256|ARBA:ARBA00023043, ECO:0000256|PROSITE-
KW ProRule:PRU00023}; Reference proteome {ECO:0000313|Proteomes:UP000189706};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT REPEAT 113..145
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 145..177
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 178..210
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 212..244
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 291..323
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT DOMAIN 418..457
FT /note="SOCS box"
FT /evidence="ECO:0000259|PROSITE:PS50225"
SQ SEQUENCE 465 AA; 50970 MW; 8971EE6C9A318D31 CRC64;
MSWSPEECRG QEEPQGGRHT LCARLVEKPD RGSEEHLEPG LGPIITRTAS GPALAFWQAV
LAGDVGSVSQ ILADSSTGLA PDSIFDTSDP ERWRDFRFNI RALRLWSLTY EEELTTPLHV
AASRGHTEVL RLLLRRRAKP DSAPGGRTAL HEACTAGHTA CVHVLLVAGA DPNTPDQDGK
RPLHLCWGPG ILECVELLLK FGAHVDGRSE DEEETPLHVA ARLGHVELAD LLLRWGACPD
ARNAEGWTPL LAACDARCQS PRDAEATTTR CFQLCSLLLS VGADADAANQ DKQRPLHLAC
RHGHSAVVEL LLSCGVSANA MDYGGHTPLH CALQGPATAL AHSPEHTVRA LLNHGAVRVW
PGALPKVLER WCVSPRTIEV LMNTYCVVQL PEESRRLVPP EIVQKHHGFY TSLFALVRQP
RSLQHLSRCA LRCHLEGSLP QALPRLPLPS SLLRYLQLEF EDVLY
//
