ID A0A1U7RJW0_ALLSI Unreviewed; 1260 AA.
AC A0A1U7RJW0;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 2.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=LOW QUALITY PROTEIN: AF4/FMR2 family member 2 {ECO:0000313|RefSeq:XP_006024724.2};
GN Name=AFF2 {ECO:0000313|RefSeq:XP_006024724.2};
OS Alligator sinensis (Chinese alligator).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Crocodylia; Alligatoridae; Alligatorinae;
OC Alligator.
OX NCBI_TaxID=38654 {ECO:0000313|Proteomes:UP000189705, ECO:0000313|RefSeq:XP_006024724.2};
RN [1] {ECO:0000313|RefSeq:XP_006024724.2}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the AF4 family. {ECO:0000256|ARBA:ARBA00007354}.
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DR RefSeq; XP_006024724.2; XM_006024662.3.
DR AlphaFoldDB; A0A1U7RJW0; -.
DR STRING; 38654.A0A1U7RJW0; -.
DR KEGG; asn:102375951; -.
DR eggNOG; ENOG502QUIB; Eukaryota.
DR InParanoid; A0A1U7RJW0; -.
DR OrthoDB; 4254515at2759; -.
DR Proteomes; UP000189705; Unplaced.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR GO; GO:0010468; P:regulation of gene expression; IEA:InterPro.
DR Gene3D; 6.10.250.2670; -; 1.
DR InterPro; IPR007797; AF4/FMR2.
DR InterPro; IPR043640; AF4/FMR2_CHD.
DR InterPro; IPR043639; AF4_int.
DR PANTHER; PTHR10528; AF4/FMR2 FAMILY MEMBER; 1.
DR PANTHER; PTHR10528:SF18; AF4_FMR2 FAMILY MEMBER 2; 1.
DR Pfam; PF05110; AF-4; 1.
DR Pfam; PF18875; AF4_int; 1.
DR Pfam; PF18876; AFF4_CHD; 1.
PE 3: Inferred from homology;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000189705}.
FT DOMAIN 997..1259
FT /note="AF4/FMR2 C-terminal homology"
FT /evidence="ECO:0000259|Pfam:PF18876"
FT REGION 114..265
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 365..713
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 800..980
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1136..1179
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 114..142
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 153..213
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 219..237
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 380..403
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 420..441
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 459..485
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 502..517
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 525..567
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 570..596
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 609..623
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 625..640
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 670..696
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 697..711
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 807..827
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 840..861
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 925..946
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 947..967
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1260 AA; 139019 MW; 34BFE5CC324A9898 CRC64;
MREYIMMANH YEQDRSALKR KEWERRNQEV QQDEDLFASG FNLFGEPYKT NKGDALANRV
QNTLGNYDEM KDLLTNHSNQ SHLVGIPKNS VPQTPIDKNE QSFFPEQRNR MIPSHQISGH
SSTSMPPPSS LSSNSALLHG HQSSRKSRTD WSRGGHNSNA AQPSQASSQQ SRSKHSSSHD
QPQSRYEDLY SCQSEQHKSG GAEEANPAAS SSHSRRHNHS KSTSSEHTYK ENSHSKSPTE
LEFVAHGPGS PLPSTSLLSA TNGLSTQNFP PGLHCKTSMV QQKPTAYVRP MDGQDQVPND
SPELKPPVEI ESGYGNQSFG TLLEGKANVP SSKNKLPKLP QASEVGLPND SSCVEEILRE
MTHSWPPPLT AIHTPGKAEQ TKFSIPSKVQ DSQHLTSGYN VQKWNEPAGK VATKSVPQKS
MLEDDLKLSS DEDDNEQAAE KTKPRNIPVN GLPLQTAHGT GLAHSSGGSG SSSESESSSE
SDSDSESSSS DSECNEESRN ATPEPEPPST NKWQLDKWLN KVNPHNKAII NNQNETHSDN
SSQSQSNQQA EGQNKGKLNS LPQTDSKDRA ILSPIREKAK PRVAQKTPEA KSSKQKSPAH
NEPTSQRTTG KKQPKKVERT SSVEEYNWPK PNNTSTTPKE KDTQEPAEQQ KVRTKASVGK
TAPRKEPRTS TGLASEKKKY RGPSKIVPKS REFIETDSST SDSNTDQEES LQAKILPACS
GPANGIKVKD SGSNILSVSS LTSNGSNTSI DQTSNDLEEQ LFSPIPIVQN ELLSPLREYE
ELKSLWVKID LSLLSRIPGQ EPFETASVKT EPREASVKHR RPSRESPTPA AVEKPSTKSK
RKHKQSESSD TYGESKKQRL EETSASCLLP PCISPIPNHR LSSTKESSTN SVKKAAKKRE
EKLFPPPLSP LLDEPVHRRH SSDNSFNQES NVTNSLQTSS SSSSTSKHRK NESKSSANPK
GLCEEESHNR PATNTLPDTS HLETDIWCAM PPLSNGNSES RRPKITFDDA LHNADYYMQE
AKKLKHKADA LLEKFGKAVN YADAALSFIE CGNAMERDPL EAKSPYTMYS ETVELIRYAM
RLKNFTGSSA TEGDKKLAVL CYRCLSLLYL RMFKLKKDHA MKYSRSLMEY FKNTSKASQV
PSPWGGNGKS TETPSPMSLS PSPASSGGSS TGPAGSSSAA TITIPERTHH MAASHVNITN
NVLRSYEHWD MADKLTKENK EFFVDLDSVM GPLTQHSSMT NLVRYVRQGL HWLRTEAHLL
//
