ID A0A1U7RP24_ALLSI Unreviewed; 635 AA.
AC A0A1U7RP24;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=Epsin-1 isoform X3 {ECO:0000313|RefSeq:XP_006026801.1};
GN Name=EPN1 {ECO:0000313|RefSeq:XP_006026801.1};
OS Alligator sinensis (Chinese alligator).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Crocodylia; Alligatoridae; Alligatorinae;
OC Alligator.
OX NCBI_TaxID=38654 {ECO:0000313|Proteomes:UP000189705, ECO:0000313|RefSeq:XP_006026801.1};
RN [1] {ECO:0000313|RefSeq:XP_006026801.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the epsin family.
CC {ECO:0000256|ARBA:ARBA00010130}.
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DR RefSeq; XP_006026801.1; XM_006026739.3.
DR AlphaFoldDB; A0A1U7RP24; -.
DR GeneID; 102371487; -.
DR CTD; 29924; -.
DR OrthoDB; 1532at2759; -.
DR Proteomes; UP000189705; Unplaced.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0008289; F:lipid binding; IEA:UniProtKB-KW.
DR CDD; cd16990; ENTH_Epsin; 1.
DR Gene3D; 1.25.40.90; -; 1.
DR InterPro; IPR013809; ENTH.
DR InterPro; IPR008942; ENTH_VHS.
DR InterPro; IPR003903; UIM_dom.
DR PANTHER; PTHR12276:SF48; EPSIN-1; 1.
DR PANTHER; PTHR12276; EPSIN/ENT-RELATED; 1.
DR Pfam; PF01417; ENTH; 1.
DR SMART; SM00273; ENTH; 1.
DR SMART; SM00726; UIM; 3.
DR SUPFAM; SSF48464; ENTH/VHS domain; 1.
DR PROSITE; PS50942; ENTH; 1.
DR PROSITE; PS50330; UIM; 3.
PE 3: Inferred from homology;
KW Lipid-binding {ECO:0000256|ARBA:ARBA00023121};
KW Reference proteome {ECO:0000313|Proteomes:UP000189705}.
FT DOMAIN 12..144
FT /note="ENTH"
FT /evidence="ECO:0000259|PROSITE:PS50942"
FT REGION 148..183
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 267..441
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 615..635
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 152..183
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 288..316
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 330..345
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 388..406
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 619..635
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 635 AA; 66244 MW; CEE9B13BAEA4A9C4 CRC64;
MSTSSLRRQM KNIVHNYSEA EIKVREATSN DPWGPSSSLM SEIADLTYNV VAFSEIMSMI
WKRLNDHGKN WRHVYKAMTL MEYLIKTGSE RVAQQCKENI YAIQTLKDFQ YVDRDGKDQG
VNVREKAKQL VALLKDDERL KEERAHALKT KEKLAQTSTA SSASSASAPT DAEQAWPQSS
GEEELQLQLA LAMSKEEAEQ PPAAAEEDLQ LQLALSLSKE EHDKEERIRR GDDLRLQMAI
EESKKETVPA RSEESSLMDL ADVFTAPAPP AIGDPWNTTA PADPWGTSGP APAGPPASDP
WGGTPSGPPP SSDPWGAAAP IPAVASADPW GGDQTTTNSD PWNSEGGGAA GSGAAPTNDP
WASVPAPTPT AQVKPPQDPW APAQTFSDPW GGSPSKPSTN GTAAGGGFEQ FGSPGETDEF
SDFDSLRTTL PKSGSSTGEL DLLAGEVPVS RVAGTKSPST FDMAAVGGSL AEVSKSTRKT
PESFLGPNAA LVDLDSLVSA KPPAAPTAKT SNPFLPTGAA PVASATAAGP VAGASTTNPF
QQPQAASLTL SQLRVSPVMA LGQPGPTVAP MVSVSPMGPG VPLTSVSPMV GMQPLAPVPT
PGLPAMGLPP MMAPPPVGPG TTSAQSLANT NPFLL
//
