ID A0A1U7RP60_ALLSI Unreviewed; 1883 AA.
AC A0A1U7RP60;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE SubName: Full=LOW QUALITY PROTEIN: plexin-A1 {ECO:0000313|RefSeq:XP_006017840.1};
GN Name=PLXNA1 {ECO:0000313|RefSeq:XP_006017840.1};
OS Alligator sinensis (Chinese alligator).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Crocodylia; Alligatoridae; Alligatorinae;
OC Alligator.
OX NCBI_TaxID=38654 {ECO:0000313|Proteomes:UP000189705, ECO:0000313|RefSeq:XP_006017840.1};
RN [1] {ECO:0000313|RefSeq:XP_006017840.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004251};
CC Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004251}.
CC -!- SIMILARITY: Belongs to the plexin family.
CC {ECO:0000256|ARBA:ARBA00010297}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00352}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR RefSeq; XP_006017840.1; XM_006017778.3.
DR STRING; 38654.A0A1U7RP60; -.
DR GeneID; 102382705; -.
DR KEGG; asn:102382705; -.
DR CTD; 5361; -.
DR eggNOG; KOG3610; Eukaryota.
DR InParanoid; A0A1U7RP60; -.
DR OrthoDB; 1387371at2759; -.
DR Proteomes; UP000189705; Unplaced.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0017154; F:semaphorin receptor activity; IEA:InterPro.
DR CDD; cd00603; IPT_PCSR; 1.
DR CDD; cd01180; IPT_plexin_repeat1; 1.
DR CDD; cd01179; IPT_plexin_repeat2; 1.
DR CDD; cd01181; IPT_plexin_repeat3; 1.
DR CDD; cd12790; RasGAP_plexin_A; 1.
DR CDD; cd11271; Sema_plexin_A1; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 5.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR014756; Ig_E-set.
DR InterPro; IPR002909; IPT_dom.
DR InterPro; IPR031148; Plexin.
DR InterPro; IPR042744; Plexin-A1_Sema.
DR InterPro; IPR013548; Plexin_cytoplasmic_RasGAP_dom.
DR InterPro; IPR046800; Plexin_RBD.
DR InterPro; IPR002165; Plexin_repeat.
DR InterPro; IPR016201; PSI.
DR InterPro; IPR008936; Rho_GTPase_activation_prot.
DR InterPro; IPR001627; Semap_dom.
DR InterPro; IPR036352; Semap_dom_sf.
DR InterPro; IPR041019; TIG1_plexin.
DR InterPro; IPR041362; TIG2_plexin.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR PANTHER; PTHR22625; PLEXIN; 1.
DR PANTHER; PTHR22625:SF35; PLEXIN-A1; 1.
DR Pfam; PF08337; Plexin_cytopl; 1.
DR Pfam; PF20170; Plexin_RBD; 1.
DR Pfam; PF01437; PSI; 3.
DR Pfam; PF01403; Sema; 1.
DR Pfam; PF01833; TIG; 4.
DR Pfam; PF18020; TIG_2; 1.
DR Pfam; PF17960; TIG_plexin; 1.
DR SMART; SM00429; IPT; 4.
DR SMART; SM00423; PSI; 3.
DR SMART; SM00630; Sema; 1.
DR SUPFAM; SSF81296; E set domains; 4.
DR SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR SUPFAM; SSF103575; Plexin repeat; 2.
DR SUPFAM; SSF101912; Sema domain; 1.
DR PROSITE; PS51004; SEMA; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000189705};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..30
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 31..1883
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5010584243"
FT TRANSMEM 1235..1259
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 24..505
FT /note="Sema"
FT /evidence="ECO:0000259|PROSITE:PS51004"
FT COILED 1256..1290
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 1883 AA; 211617 MW; 37C9803957BBADF0 CRC64;
MWLLRLKHHL SVNIWTLLLL GSAWLPLAEG APKSPFRTFS VTDWSLTHLV VHNKTGEVYV
GAVNRIYKLS NNLTQLRIHV TGPVDDNEKC YPPPSVQSCP HGLVTTNNVN KLLLVDYSEN
RLIACGSASQ GICQFLRLDD LFKLGEPHHR KEHYLSSVNE SGTMSGVIIE VSNGQNKLFI
GTPIDGKSEY FPTLSSRKLM ANEENAEMFG FVYQDEFVSS QLKIPSDTLS KFPTFDIYYI
YSFSSEQFVY YLTLQLDTQL TSPDSTGEQF FTSKIVRLCV DDPKFYSYVE FPIGCVRDGI
EYRLIQDAYL TKPGKALAKQ LGIMEREDIL FTIFSQGQKN RVKPPKESVL CLFTLKKIKD
KIKERIQSCY RGEGKLSLPW LLNKELGCIN SPLQIDDNFC GQDFNQPLGG TITIEGTPLF
VDKEDGMTSV AAYDYRGHTV VFAGTRSGRI KKILVNLSST GGHPALQYEN VVAHEGSSIL
RDLVLSPDRQ HIYAMTEKQV TRVPVESCEQ YKSCALCLGS RDPHCGWCVL HNVCSRKDRC
ERADEPQRFA SDLRQCVELT VQPKNISVTM SEVPLVLQAW NVPDLSAGVN CSFEDFTESE
SRIEDGRIYC SSPSAKDVIP ITRGRGDKRV VKLYLKSKET GKKFASVDFV FYNCSVHQSC
LSCVNGSFPC HWCKYRHICT HNAAECSFQE GRVNMSEDCP QILPSTQIYI PVGVVKPITL
TAKNLPQPQS GQRNYECIFH IPGSTTRVTA LRFNSTSIQC QNTSYFYEGN DISDLPVNLS
VVWNGNFVID NPQNIQAHLY KCSALRESCG LCLKADPRFE CGWCVTEKRC SLRQHCLAYE
SSWMHASNGN SRCTDPKILK LSPETGPRQG GTRLTITGEN LGLKFEDVRW GVRVGKVVCN
PIESEYISAE QIVCEIGDAS PSKIHEARVE VCIRDCSPSY RATSPKSFTF VTPTFSRVIP
ARGPLSGGTW IVIEGNHLNA GSNVTVTIGG RPCAFSWRSA REIRCRTPPG QSPGGSPILI
NINRAELSNP EVKYNYTEDP TIQKIDPEWS INSGGTLLTV IGTNLATIKE PKIRAKYGSS
ERENNCTVYN DTTMLCYAPS IDNPVRSPPE IGDRPDEIGF VMDNVQALLI VNTTNFVYYP
DPVFEPLSPS GMLELKPSSP LILKGRNLLP PATGNSRLNY TVLIGETPCA LTVSETQLLC
ESPNLTGQHK VTIKAGGFEF SPGTLQIYSD SLLTLPAIIG IGGGGGLLLL IIIIVLIAYK
RKSRDADRTL KRLQLQMDNL ESRVALECKE AFAELQTDIH ELTNDLDGAG IPFLDYRTYA
MRVLFPGIED HPVLKEMEVQ ANVEKSLTLF GQLLNKKHFL XXXXXXXXXX XSMRDRGNVA
SLIMTALQGE MEYATGVLKQ LLSDLIEKNL ESKNHPKLLL RRTESVAEKM LTNWFTFLLY
KFLKECAGEP LFMLYCAIKQ QMEKGPIDAI TGEARYSLSE DKLIRQQIDY KMLTLNCVNP
ENENAPEIPV KVLNCDTITQ VKEKLLDAVY KGVPYSQRPK AGDMDLEWRQ GRMARIILQD
EDVTTKIDND WKRLNTLAHY QVTDGSSVAL VPKQNSAYNI SNSSTFTKSL SRYESMLRTA
SSPDSLRSRT PMITPDLESG TKLWHLVKNH DHMDQREGDR GSKMVSEIYL TRLLATKGTL
QKFVDDLFET IFSTAHRGSA LPLAIKYMFD FLDEQADKHQ INDYDVRHTW KSNCLPLRFW
VNVIKNPQFV FDIHKNSITD ACLSVVAQTF MDSCSTSEQQ LGKXNKLLYA KDIPNYKSWV
ERYYADIAKM PAISDQDMSA YLAEQSRLHL SQFNSMSALH EIYSYITKYK DEILAALEKD
EQARRQRLRS KLEQAIDTMA LSS
//
