ID A0A1U7RQE3_ALLSI Unreviewed; 691 AA.
AC A0A1U7RQE3;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Cleavage and polyadenylation specificity factor subunit 3 isoform X1 {ECO:0000313|RefSeq:XP_006018469.1};
GN Name=CPSF3 {ECO:0000313|RefSeq:XP_006018469.1};
OS Alligator sinensis (Chinese alligator).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Crocodylia; Alligatoridae; Alligatorinae;
OC Alligator.
OX NCBI_TaxID=38654 {ECO:0000313|Proteomes:UP000189705, ECO:0000313|RefSeq:XP_006018469.1};
RN [1] {ECO:0000313|RefSeq:XP_006018469.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR RefSeq; XP_006018469.1; XM_006018407.3.
DR AlphaFoldDB; A0A1U7RQE3; -.
DR STRING; 38654.A0A1U7RQE3; -.
DR GeneID; 102371539; -.
DR KEGG; asn:102371539; -.
DR CTD; 51692; -.
DR eggNOG; KOG1137; Eukaryota.
DR InParanoid; A0A1U7RQE3; -.
DR OrthoDB; 169081at2759; -.
DR Proteomes; UP000189705; Unplaced.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR CDD; cd16292; CPSF3-like_MBL-fold; 1.
DR Gene3D; 3.40.50.10890; -; 1.
DR Gene3D; 3.60.15.10; Ribonuclease Z/Hydroxyacylglutathione hydrolase-like; 1.
DR InterPro; IPR022712; Beta_Casp.
DR InterPro; IPR021718; CPSF73-100_C.
DR InterPro; IPR001279; Metallo-B-lactamas.
DR InterPro; IPR036866; RibonucZ/Hydroxyglut_hydro.
DR InterPro; IPR011108; RMMBL.
DR PANTHER; PTHR11203; CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR FAMILY MEMBER; 1.
DR PANTHER; PTHR11203:SF11; CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR SUBUNIT 3; 1.
DR Pfam; PF10996; Beta-Casp; 1.
DR Pfam; PF11718; CPSF73-100_C; 1.
DR Pfam; PF00753; Lactamase_B; 1.
DR Pfam; PF07521; RMMBL; 1.
DR SMART; SM01027; Beta-Casp; 1.
DR SMART; SM01098; CPSF73-100_C; 1.
DR SMART; SM00849; Lactamase_B; 1.
DR SUPFAM; SSF56281; Metallo-hydrolase/oxidoreductase; 1.
PE 4: Predicted;
KW mRNA processing {ECO:0000256|ARBA:ARBA00022664};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000189705}.
FT DOMAIN 31..217
FT /note="Metallo-beta-lactamase"
FT /evidence="ECO:0000259|SMART:SM00849"
FT DOMAIN 253..374
FT /note="Beta-Casp"
FT /evidence="ECO:0000259|SMART:SM01027"
FT DOMAIN 484..690
FT /note="Pre-mRNA 3'-end-processing endonuclease
FT polyadenylation factor C-term"
FT /evidence="ECO:0000259|SMART:SM01098"
SQ SEQUENCE 691 AA; 77959 MW; 41FAF92E0934F188 CRC64;
MSAKRKADAM IPAEESDQLL IRPLGAGQEV GRSCIILEFK GRKIMLDCGI HPGLEGMDAL
PYIDLIDPAE IDLLLISHFH LDHCGALPWF LQKTSFKGRT FMTHATKAIY RWLLSDYVKV
SNISADDMLY TETDLEESMD KIETINFHEV KEVAGIKFWC YHAGHVLGAA MFMIEIAGVK
LLYTGDFSRQ EDRHLMAAEI PTIKPDILII ESTYGTHIHE KREEREARFC NTVHDIVNRG
GRGLIPVFAL GRAQELLLIL DEYWQNHPEL HDIPIYYASS LAKKCMAVYQ TYVNAMNDKI
RKQININNPF VFKHISNLKS MDHFDDIGPS VVMASPGMMQ SGLSRELFES WCTDKRNGVI
IAGYCVEGTL AKHIMSEPEE ITTMSGQKLP LKMSVDYISF SAHTDYQQTS EFIRALKPPH
VILVHGEQNE MARLKAALIR EYEDNDEVHI EVHNPRNTEA VTLNFRGEKL AKVMGSLADK
KPEQGQRISG ILVKRNFNYH ILSPCDLSNY TDLAMSTVTQ TQAIPYTGPF SLLYYQLQKL
TGDVEEIEVQ QKPALKVFKN ITVIQEPGMV VLEWVANPAN DMYADTVTTV ILEVQSNPKI
QKAAIHKISK QVDIDVYSKR LEIMLQDMFG EDCVSGKEGS ILSVAVDGKT ANISLETRTV
ECEPGCEDDE ALREMVELAA QRLYDALSPV H
//
