ID   A0A1U7RYJ9_ALLSI        Unreviewed;      1206 AA.
AC   A0A1U7RYJ9;
DT   10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT   10-MAY-2017, sequence version 1.
DT   27-MAR-2024, entry version 31.
DE   RecName: Full=Cullin-associated NEDD8-dissociated protein 1 {ECO:0000256|ARBA:ARBA00040131};
DE   AltName: Full=Cullin-associated and neddylation-dissociated protein 1 {ECO:0000256|ARBA:ARBA00042178};
GN   Name=CAND1 {ECO:0000313|RefSeq:XP_006022534.1};
OS   Alligator sinensis (Chinese alligator).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Crocodylia; Alligatoridae; Alligatorinae;
OC   Alligator.
OX   NCBI_TaxID=38654 {ECO:0000313|Proteomes:UP000189705, ECO:0000313|RefSeq:XP_006022534.1};
RN   [1] {ECO:0000313|RefSeq:XP_006022534.1}
RP   IDENTIFICATION.
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC       Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC   -!- SIMILARITY: Belongs to the CAND family.
CC       {ECO:0000256|ARBA:ARBA00007657}.
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DR   RefSeq; XP_006022534.1; XM_006022472.2.
DR   AlphaFoldDB; A0A1U7RYJ9; -.
DR   STRING; 38654.A0A1U7RYJ9; -.
DR   GeneID; 102370142; -.
DR   KEGG; asn:102370142; -.
DR   CTD; 55832; -.
DR   eggNOG; KOG1824; Eukaryota.
DR   InParanoid; A0A1U7RYJ9; -.
DR   OrthoDB; 68829at2759; -.
DR   Proteomes; UP000189705; Unplaced.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0010265; P:SCF complex assembly; IEA:InterPro.
DR   Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR   InterPro; IPR011989; ARM-like.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR039852; CAND1/CAND2.
DR   InterPro; IPR013932; TATA-bd_TIP120.
DR   PANTHER; PTHR12696:SF1; CULLIN-ASSOCIATED NEDD8-DISSOCIATED PROTEIN 1; 1.
DR   PANTHER; PTHR12696; TIP120; 1.
DR   Pfam; PF13513; HEAT_EZ; 1.
DR   Pfam; PF08623; TIP120; 1.
DR   SUPFAM; SSF48371; ARM repeat; 1.
PE   3: Inferred from homology;
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW   Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW   Reference proteome {ECO:0000313|Proteomes:UP000189705};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT   DOMAIN          1016..1178
FT                   /note="TATA-binding protein interacting (TIP20)"
FT                   /evidence="ECO:0000259|Pfam:PF08623"
FT   REGION          291..320
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        291..318
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1206 AA;  133558 MW;  EEA603E95880F0DB CRC64;
     MATNDLMTEL QKDSIKLDDD SERKVVKMIL KLLEDKNGEV QNLAVKCLGP LVSKVKEYQV
     ETIVDTLCTN MLSDKEQLRD ISSIGLKTVI GELPPASSGS ALAANVCKKI TGRLTSAIAK
     QEDVSVQLEA LDIMADMLSR QGGLLVNFHP SILTCLLPQL TSPRLAVRKR TIIALGHLVM
     SCGNIVFVDL IEHLLTELSK NDSMSTTRTY IQCIAAISRQ AGHRIGEYLE KIIPLVVKFC
     NVDDDELREY CIQAFESFVR RCPKEVYPHV STIINICLKY LTYDPNYNYD DEDEDENAMD
     ADGGDDDDQG SDDEYSDDDD MSWKVRRAAA KCLDAVVSTR HEMLPEFYKT VSPALIARFK
     EREENVKADV FHAYLSLLKQ TRPVQSWLCD PDAMEQGETP LTMLQSQVPN IVKALHKQMK
     EKSVKTRQCC FNMLTELVNV LPGALTQHVP VLVPGIIFSL NDKSSSSNLK IDALSCLYVI
     LCNHSPQVFH PHVQALVPPV VACVGDPFYK ITSEALLVTQ QLVKVIRPLD QPSSFDATPY
     IKDLFTCTIK RLKAADIDQE VKERAISCMG QIICSLGDNL GTDLPNTLQI FLERLKNEIT
     RLTTVKALTL IAGSPLKIDL RPVLGEGVPI LASFLRKNQR ALKLGTLSAL DILIKNYSDS
     LTAAMIDAVL DELPPLISES DMHVSQMAIS FLTTLAKVYP SSLSKISGSI LNELIGLVRS
     PLLQGGALSA MLEFFQALVV TGTNNLGYMD LLRMLTGPVY SQSTALTHKQ SYYSIAKCVA
     ALTRACPKEG PAVVGQFIQD VKNSRSTDSI RLLALLSLGE VGHHIDLSGQ IELKSVILEA
     FSSPSEEVKS AASYALGSIS VGNLPEYLPF VLQEITSQPK RQYLLLHSLK EIISSASVVG
     LKPYVENIWA LLLKHCECAE EGTRNVVAEC LGKLTLIDPE TLLPRLKGYL ASGSSYARSS
     VVTAVKFTIS DHPQPIDPLL KNCIGDFLKT LEDPDLNVRR VALVTFNSAA HNKPSLIRDL
     LDTVLPHLYN ETKVRKELIR EVEMGPFKHT VDDGLDIRKA AFECMYTLLD SCLDRLDIFE
     FLNHVEDGLK DHYDIKMLTF LMLVRLSTLC PSAVLQRLDR LVEPLRATCT TKVKANSVKQ
     EFEKQDELKR SAMRAVAALL TIPEAEKSPL MSEFQSQISS NPELAAIFES IQKDSSSTNL
     ESMDTS
//