ID A0A1U7RYQ1_ALLSI Unreviewed; 530 AA.
AC A0A1U7RYQ1;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE SubName: Full=Cryptochrome-1-like {ECO:0000313|RefSeq:XP_006021416.1, ECO:0000313|RefSeq:XP_025057054.1};
GN Name=LOC102382870 {ECO:0000313|RefSeq:XP_006021416.1,
GN ECO:0000313|RefSeq:XP_025057054.1};
OS Alligator sinensis (Chinese alligator).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Crocodylia; Alligatoridae; Alligatorinae;
OC Alligator.
OX NCBI_TaxID=38654 {ECO:0000313|RefSeq:XP_006021416.1};
RN [1] {ECO:0000313|RefSeq:XP_006021416.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (APR-2022) to UniProtKB.
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|PIRSR:PIRSR602081-1};
CC Note=Binds 1 FAD per subunit. {ECO:0000256|PIRSR:PIRSR602081-1};
CC -!- SIMILARITY: Belongs to the DNA photolyase class-1 family.
CC {ECO:0000256|ARBA:ARBA00005862}.
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DR RefSeq; XP_006021416.1; XM_006021354.3.
DR RefSeq; XP_025057054.1; XM_025201269.1.
DR STRING; 38654.A0A1U7RYQ1; -.
DR GeneID; 102382870; -.
DR KEGG; asn:102382870; -.
DR eggNOG; KOG0133; Eukaryota.
DR OrthoDB; 124765at2759; -.
DR Proteomes; UP000189705; Unplaced.
DR Gene3D; 1.25.40.80; -; 1.
DR Gene3D; 1.10.579.10; DNA Cyclobutane Dipyrimidine Photolyase, subunit A, domain 3; 1.
DR Gene3D; 3.40.50.620; HUPs; 1.
DR InterPro; IPR036134; Crypto/Photolyase_FAD-like_sf.
DR InterPro; IPR036155; Crypto/Photolyase_N_sf.
DR InterPro; IPR005101; Cryptochr/Photolyase_FAD-bd.
DR InterPro; IPR002081; Cryptochrome/DNA_photolyase_1.
DR InterPro; IPR006050; DNA_photolyase_N.
DR InterPro; IPR014729; Rossmann-like_a/b/a_fold.
DR PANTHER; PTHR11455; CRYPTOCHROME; 1.
DR PANTHER; PTHR11455:SF52; CRYPTOCHROME CIRCADIAN REGULATOR 5; 1.
DR Pfam; PF00875; DNA_photolyase; 1.
DR Pfam; PF03441; FAD_binding_7; 1.
DR SUPFAM; SSF48173; Cryptochrome/photolyase FAD-binding domain; 1.
DR SUPFAM; SSF52425; Cryptochrome/photolyase, N-terminal domain; 1.
DR PROSITE; PS51645; PHR_CRY_ALPHA_BETA; 1.
PE 3: Inferred from homology;
KW Chromophore {ECO:0000256|ARBA:ARBA00022991};
KW FAD {ECO:0000256|ARBA:ARBA00022827, ECO:0000256|PIRSR:PIRSR602081-1};
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630, ECO:0000256|PIRSR:PIRSR602081-
KW 1}; Reference proteome {ECO:0000313|Proteomes:UP000189705}.
FT DOMAIN 3..132
FT /note="Photolyase/cryptochrome alpha/beta"
FT /evidence="ECO:0000259|PROSITE:PS51645"
FT REGION 487..530
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 494..508
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 248..252
FT /ligand="FAD"
FT /ligand_id="ChEBI:CHEBI:57692"
FT /evidence="ECO:0000256|PIRSR:PIRSR602081-1"
FT BINDING 288..295
FT /ligand="FAD"
FT /ligand_id="ChEBI:CHEBI:57692"
FT /evidence="ECO:0000256|PIRSR:PIRSR602081-1"
FT BINDING 386..388
FT /ligand="FAD"
FT /ligand_id="ChEBI:CHEBI:57692"
FT /evidence="ECO:0000256|PIRSR:PIRSR602081-1"
FT SITE 319
FT /note="Electron transfer via tryptophanyl radical"
FT /evidence="ECO:0000256|PIRSR:PIRSR602081-2"
FT SITE 373
FT /note="Electron transfer via tryptophanyl radical"
FT /evidence="ECO:0000256|PIRSR:PIRSR602081-2"
FT SITE 396
FT /note="Electron transfer via tryptophanyl radical"
FT /evidence="ECO:0000256|PIRSR:PIRSR602081-2"
SQ SEQUENCE 530 AA; 60772 MW; 4DF1E12A094B2704 CRC64;
MKHSCIHWFR KGLRLHDNPA LLAAMKDCSE LYPIFILDPW FPKNMQVSVN RWRFLVESLK
DLDESLKKLK SRLFVVRGHP AEVFPGLFKA WKVTRLTFEV DTEPYSKQRD AEVVRLAAAH
GVQVIQKVSH TLYDTDRVIA ENNGKVPLTY RQLQAVLAGL GPPKQPVLAP TLETMKDCCT
PGRDNRDPKY EIPTLEELGQ DPKEAGPCLY PGGESEALSR LDFHMKRMTW VCNFKKPDTE
PNTLSPSTTV LSPYVKFGCL SVRTFWWKLT EIYRGKKHSS PPVSLHGQLL WREFFYTAGA
GIPNFNRMEG NPICVQVDWD DNPEYVKAWK EGRTGYPFID AIMTQLRTEG WIHHLARHAV
ACFLTRGDLW VSWEEGQKVF EELLLDADWS LNAGNWQWLS ASAFFHQFFR VYSPVAFGKK
TDKSGAYIKK YLPILRKFPA EYIYEPWKAP RSMQEQAGCI IGRDYPRPIV EHEALSKRNI
MRMKAAYAQR SHSKAAQVEK ESTKKGGKRK LPAGPSVVEL LTKKPKAKSS
//
