ID A0A1U7RZC8_ALLSI Unreviewed; 589 AA.
AC A0A1U7RZC8;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE SubName: Full=Cleavage stimulation factor subunit 2 isoform X1 {ECO:0000313|RefSeq:XP_006026574.1};
GN Name=CSTF2 {ECO:0000313|RefSeq:XP_006026574.1};
OS Alligator sinensis (Chinese alligator).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Crocodylia; Alligatoridae; Alligatorinae;
OC Alligator.
OX NCBI_TaxID=38654 {ECO:0000313|Proteomes:UP000189705, ECO:0000313|RefSeq:XP_006026574.1};
RN [1] {ECO:0000313|RefSeq:XP_006026574.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR RefSeq; XP_006026574.1; XM_006026512.3.
DR AlphaFoldDB; A0A1U7RZC8; -.
DR STRING; 38654.A0A1U7RZC8; -.
DR GeneID; 102377980; -.
DR KEGG; asn:102377980; -.
DR CTD; 1478; -.
DR eggNOG; KOG0108; Eukaryota.
DR InParanoid; A0A1U7RZC8; -.
DR OrthoDB; 179465at2759; -.
DR Proteomes; UP000189705; Unplaced.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0031124; P:mRNA 3'-end processing; IEA:InterPro.
DR CDD; cd12671; RRM_CSTF2_CSTF2T; 1.
DR Gene3D; 1.25.40.630; -; 1.
DR Gene3D; 3.30.70.330; -; 1.
DR Gene3D; 1.10.20.70; Transcription termination and cleavage factor, C-terminal domain; 1.
DR InterPro; IPR025742; CSTF2_hinge.
DR InterPro; IPR026896; CSTF_C.
DR InterPro; IPR038192; CSTF_C_sf.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR000504; RRM_dom.
DR PANTHER; PTHR45735; CLEAVAGE STIMULATION FACTOR SUBUNIT 2; 1.
DR PANTHER; PTHR45735:SF2; RRM DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF14327; CSTF2_hinge; 1.
DR Pfam; PF14304; CSTF_C; 1.
DR Pfam; PF00076; RRM_1; 1.
DR SMART; SM00360; RRM; 1.
DR SUPFAM; SSF54928; RNA-binding domain, RBD; 1.
DR PROSITE; PS50102; RRM; 1.
PE 4: Predicted;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000189705};
KW RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00176}.
FT DOMAIN 16..94
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT REGION 198..453
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 466..489
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 514..547
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 202..220
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 221..240
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 266..284
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 333..353
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 421..453
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 589 AA; 61917 MW; BF774E8628FC1431 CRC64;
MAGLAVRDPA VDRSLRSVFV GNIPYEATEE QLKDIFSEVG PVVSFRLVYD RETGKPKGYG
FCEYQDQETA LSAMRNLNGR EFSGRALRVD NAASEKNKEE LKSLGTGAPI IESPYGDPVN
PEDAPESISR AVASLPPEQM FELMKQMKLC VQNSPQEARN MLLQNPQLAY ALLQAQVVMR
IVDPEIALKI LHRQTSVPPL IPGNQQPVPG PGPGPGPGPG PNAQMNQQTP PSSQPQTIGG
MHVNGAPPLM QPPMQGGVPA PGQMPTSVQG PGPGPGPGPG PMAPGGGMQP QVGMPGGGPV
PMERGQGNLQ LSPVGPARPA SIERVQVPMP DPRAPMQRGP LPASGPPPRG LLGDAPNDPR
GGTLLSVTGE VEPRGYLGPP HQGPPMHHMP GHDNRGPPHE MRGGPMGEPR PLMGEPRGPL
MDARGGRDPR GMEPRGMEPR GMEPRGMDTR GMEPRVMEPR GMEARGMEPR AMEPRGPGPN
SRGPMPGGIQ GPGPLNMGAN VPQGPRQVPN MPGAGMQGGG LPGAGVQGAG QPGGFSPGQN
QVTPQDHEKA ALIMQVLQLT ADQIAMLPPE QRQSILILKE QIQKSTGAP
//
