ID A0A1U7S392_ALLSI Unreviewed; 415 AA.
AC A0A1U7S392;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE RecName: Full=Zona pellucida-like domain-containing protein 1 {ECO:0000256|ARBA:ARBA00040851};
DE AltName: Full=Cupulin {ECO:0000256|ARBA:ARBA00043069};
GN Name=ZPLD1 {ECO:0000313|RefSeq:XP_006033967.1,
GN ECO:0000313|RefSeq:XP_025071576.1};
OS Alligator sinensis (Chinese alligator).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Crocodylia; Alligatoridae; Alligatorinae;
OC Alligator.
OX NCBI_TaxID=38654 {ECO:0000313|RefSeq:XP_006033967.1};
RN [1] {ECO:0000313|RefSeq:XP_006033967.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (APR-2022) to UniProtKB.
CC -!- FUNCTION: Glycoprotein which is a component of the gelatinous
CC extracellular matrix in the cupulae of the vestibular organ.
CC {ECO:0000256|ARBA:ARBA00037652}.
CC -!- SUBCELLULAR LOCATION: Cytoplasmic vesicle membrane
CC {ECO:0000256|ARBA:ARBA00004358}; Single-pass type I membrane protein
CC {ECO:0000256|ARBA:ARBA00004358}. Secreted, extracellular space,
CC extracellular matrix {ECO:0000256|ARBA:ARBA00004498}.
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DR RefSeq; XP_006033967.1; XM_006033905.2.
DR RefSeq; XP_025071576.1; XM_025215791.1.
DR STRING; 38654.A0A1U7S392; -.
DR GeneID; 102383148; -.
DR KEGG; asn:102383148; -.
DR CTD; 131368; -.
DR eggNOG; ENOG502QQQ1; Eukaryota.
DR OrthoDB; 5345199at2759; -.
DR Proteomes; UP000189705; Unplaced.
DR GO; GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.
DR Gene3D; 2.60.40.4100; Zona pellucida, ZP-C domain; 1.
DR InterPro; IPR042235; ZP-C.
DR InterPro; IPR001507; ZP_dom.
DR PANTHER; PTHR14002; ENDOGLIN/TGF-BETA RECEPTOR TYPE III; 1.
DR PANTHER; PTHR14002:SF24; ZONA PELLUCIDA-LIKE DOMAIN-CONTAINING PROTEIN 1; 1.
DR Pfam; PF00100; Zona_pellucida; 1.
DR SMART; SM00241; ZP; 1.
DR PROSITE; PS51034; ZP_2; 1.
PE 4: Predicted;
KW Cytoplasmic vesicle {ECO:0000256|ARBA:ARBA00023329};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000189705};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..16
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 17..415
FT /note="Zona pellucida-like domain-containing protein 1"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5041056008"
FT TRANSMEM 373..396
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 43..320
FT /note="ZP"
FT /evidence="ECO:0000259|PROSITE:PS51034"
SQ SEQUENCE 415 AA; 46007 MW; 3269F934045C6CF7 CRC64;
MEQVWLLLLL TIKVLSVTTQ FNGYNCDANL HSRFPAERDI NVYCGVQAIT MKINFCTVLF
SGYSETDLAL NGKHGDAHCR GFINNNTFPA VVIFIINLST LETCGNTLVV STVPGVNAYG
NVSMVQIGNV SGYIDTPDPP TIISYLPGLL YKFSCSYPLE YLVNNTQLAS SSAAISVREN
NGTFISTLNL LLYNDSTYSQ QLIIPSTGLP LKTKIYAAVR ATNLDGRWNV LMDYCYTTPS
GNPNDFLRYD LFFSCDKDPQ TTIIENGKSQ MGRFSFEVFR FVKHKNQKMS TVFLHCVTKL
CRSDDCPFLV PICSNRERRD AMRRTTWSTL STSGNAVISA GPIITRSDET PTNNSQLVHP
NGPPFHLNSV TSALISGIVI LGVMSIFLFV CSLTLLHRKW PSNSVLDGIQ NPVFN
//
