ID A0A1U7S3T7_ALLSI Unreviewed; 434 AA.
AC A0A1U7S3T7;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE SubName: Full=Keratin, type I cytoskeletal 18 {ECO:0000313|RefSeq:XP_006030669.1};
GN Name=KRT18 {ECO:0000313|RefSeq:XP_006030669.1};
OS Alligator sinensis (Chinese alligator).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Crocodylia; Alligatoridae; Alligatorinae;
OC Alligator.
OX NCBI_TaxID=38654 {ECO:0000313|Proteomes:UP000189705, ECO:0000313|RefSeq:XP_006030669.1};
RN [1] {ECO:0000313|RefSeq:XP_006030669.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the intermediate filament family.
CC {ECO:0000256|RuleBase:RU000685}.
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DR RefSeq; XP_006030669.1; XM_006030607.3.
DR AlphaFoldDB; A0A1U7S3T7; -.
DR STRING; 38654.A0A1U7S3T7; -.
DR GeneID; 102375632; -.
DR KEGG; asn:102375632; -.
DR CTD; 3875; -.
DR eggNOG; ENOG502QUS8; Eukaryota.
DR InParanoid; A0A1U7S3T7; -.
DR OrthoDB; 4640531at2759; -.
DR Proteomes; UP000189705; Unplaced.
DR GO; GO:0005882; C:intermediate filament; IEA:UniProtKB-KW.
DR GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR Gene3D; 1.20.5.170; -; 1.
DR Gene3D; 1.20.5.500; Single helix bin; 1.
DR Gene3D; 1.20.5.1160; Vasodilator-stimulated phosphoprotein; 1.
DR InterPro; IPR018039; IF_conserved.
DR InterPro; IPR039008; IF_rod_dom.
DR InterPro; IPR002957; Keratin_I.
DR PANTHER; PTHR23239; INTERMEDIATE FILAMENT; 1.
DR PANTHER; PTHR23239:SF349; KERATIN, TYPE I CYTOSKELETAL 18; 1.
DR Pfam; PF00038; Filament; 1.
DR PRINTS; PR01248; TYPE1KERATIN.
DR SMART; SM01391; Filament; 1.
DR SUPFAM; SSF64593; Intermediate filament protein, coiled coil region; 2.
DR PROSITE; PS00226; IF_ROD_1; 1.
DR PROSITE; PS51842; IF_ROD_2; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Intermediate filament {ECO:0000256|ARBA:ARBA00022754,
KW ECO:0000256|RuleBase:RU000685};
KW Reference proteome {ECO:0000313|Proteomes:UP000189705}.
FT DOMAIN 86..397
FT /note="IF rod"
FT /evidence="ECO:0000259|PROSITE:PS51842"
FT REGION 1..23
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 83..124
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 195..233
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 302..382
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 434 AA; 48723 MW; A09C1F00B2FF18BA CRC64;
MSISRSVYSS TRRPVSSSQG FTTTRKTTAA SVYAGAGGSG SRISMPWGSR GVYGANSIYL
GASGGSGGGY GASGIYLGGS AVIHNEKETM QDLNDRLASY LEKVRSLETA NHNLEVQIRE
FLDKKGPSTQ DWTHYWDIIE DLRNKIYEES VDNARIVLQI DNARLAADDF RVKYEGELAI
RQSVEADIAG LRKVIDDTNM SRLQLESEIE NLKEELIYMK KNHEEEAKSL QAQVSGSGLT
VEVDSPKTHD LGKIMTDIRA QYEALAQKNR EDLDKYWNQQ ITESTIEITQ STKDMDTAHG
TLTELRRTYQ TLEIELESLR NLKGSLEANL MEVENRYGMQ LEHLNGLLLR TEAELMQVRT
EVQRQAEEYQ ALLNIKVKLE AEIATYRRLL EGGEEFSLKD ALAEDSSHKV YIQTSKQIVD
GKLVSETTET RALK
//
