ID A0A1U7S524_ALLSI Unreviewed; 609 AA.
AC A0A1U7S524;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE SubName: Full=Nuclear protein localization protein 4 homolog isoform X1 {ECO:0000313|RefSeq:XP_006034863.1};
GN Name=NPLOC4 {ECO:0000313|RefSeq:XP_006034863.1};
OS Alligator sinensis (Chinese alligator).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Crocodylia; Alligatoridae; Alligatorinae;
OC Alligator.
OX NCBI_TaxID=38654 {ECO:0000313|Proteomes:UP000189705, ECO:0000313|RefSeq:XP_006034863.1};
RN [1] {ECO:0000313|RefSeq:XP_006034863.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the NPL4 family.
CC {ECO:0000256|ARBA:ARBA00011025}.
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DR RefSeq; XP_006034863.1; XM_006034801.3.
DR AlphaFoldDB; A0A1U7S524; -.
DR STRING; 38654.A0A1U7S524; -.
DR GeneID; 102369078; -.
DR KEGG; asn:102369078; -.
DR CTD; 55666; -.
DR eggNOG; KOG2834; Eukaryota.
DR InParanoid; A0A1U7S524; -.
DR OrthoDB; 5400828at2759; -.
DR Proteomes; UP000189705; Unplaced.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
DR CDD; cd08061; MPN_NPL4; 1.
DR Gene3D; 3.40.140.10; Cytidine Deaminase, domain 2; 1.
DR Gene3D; 2.30.30.380; Zn-finger domain of Sec23/24; 1.
DR InterPro; IPR037518; MPN.
DR InterPro; IPR016563; Npl4.
DR InterPro; IPR007717; NPL4_C.
DR InterPro; IPR024682; Npl4_Ub-like_dom.
DR InterPro; IPR007716; NPL4_Zn-bd_put.
DR InterPro; IPR029071; Ubiquitin-like_domsf.
DR InterPro; IPR001876; Znf_RanBP2.
DR InterPro; IPR036443; Znf_RanBP2_sf.
DR PANTHER; PTHR12710; NUCLEAR PROTEIN LOCALIZATION 4; 1.
DR PANTHER; PTHR12710:SF0; NUCLEAR PROTEIN LOCALIZATION PROTEIN 4 HOMOLOG; 1.
DR Pfam; PF05021; NPL4; 1.
DR Pfam; PF11543; UN_NPL4; 1.
DR Pfam; PF05020; zf-NPL4; 1.
DR PIRSF; PIRSF010052; Polyub_prc_Npl4; 1.
DR SMART; SM00547; ZnF_RBZ; 1.
DR SUPFAM; SSF90209; Ran binding protein zinc finger-like; 1.
DR SUPFAM; SSF54236; Ubiquitin-like; 1.
DR PROSITE; PS50249; MPN; 1.
DR PROSITE; PS01358; ZF_RANBP2_1; 1.
DR PROSITE; PS50199; ZF_RANBP2_2; 1.
PE 3: Inferred from homology;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000189705};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00322};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00322}.
FT DOMAIN 227..364
FT /note="MPN"
FT /evidence="ECO:0000259|PROSITE:PS50249"
FT DOMAIN 581..609
FT /note="RanBP2-type"
FT /evidence="ECO:0000259|PROSITE:PS50199"
SQ SEQUENCE 609 AA; 68475 MW; D39B590D3E300FB3 CRC64;
MAETIIIRVQ SPEGVKRITA TKRETVSTFL KKVAKEFGFR NNGFSIYTNR NRTGEITASQ
NKSLNLLKIK HGDMLFLYPS SPAGSSSENM DISISQGLRP TGAPQVVEDE IDQYLIKQDG
KIYRNRDQQL CRHGPLGKCV HCVPLEPFDE DYLNHLEPPV KHMSFHAYIR KLTGGADKGK
FVALENISCK IKSGCEGHPP WPEGICTKCQ PSAITLNRQK YRHVDNIMFE NHTIADRFLD
FWRKTGNQHL GYLYGRYTEH KDIPLGIRAE VAAIYEPPQI GTQNSLEILE DPKAEVVDEI
AAKLGLRKVG WIFTDLVSED TRKGTVRYSR NKDAYFLSAE ECITAGNFQN QQPNICRLSP
DGHFGSKFVT VVATGGPDNQ VHFEGYQVSN QCMALVRDEC LLPCRDAPEL GYAKESSSEQ
YVPDVFYKDI DKFGNEITQL ARPLPVEYLI IDITTTFPKD PVYTFSISQS PFPIENHDVL
GETQDFHSLA TYLSQNTSSV FLDVISDFHL LLFLVTNEVM PLRDSISLLL EAVRTKNEEL
AQTWKKSEQW ATIEQLCSTV GVQLSGLHEY GAVGSSQHAA ATAVWACQHC TFMNQPGTDH
CEMCSLPRT
//
