GenomeNet

Database: UniProt
Entry: A0A1U7S5Z1_ALLSI
LinkDB: A0A1U7S5Z1_ALLSI
Original site: A0A1U7S5Z1_ALLSI 
ID   A0A1U7S5Z1_ALLSI        Unreviewed;       394 AA.
AC   A0A1U7S5Z1;
DT   10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT   10-MAY-2017, sequence version 1.
DT   08-MAY-2019, entry version 13.
DE   SubName: Full=ATP-sensitive inward rectifier potassium channel 11 {ECO:0000313|RefSeq:XP_006024938.1};
GN   Name=KCNJ11 {ECO:0000313|RefSeq:XP_006024938.1};
OS   Alligator sinensis (Chinese alligator).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Crocodylia; Alligatoridae; Alligatorinae;
OC   Alligator.
OX   NCBI_TaxID=38654 {ECO:0000313|Proteomes:UP000189705, ECO:0000313|RefSeq:XP_006024938.1};
RN   [1] {ECO:0000313|RefSeq:XP_006024938.1}
RP   IDENTIFICATION.
RG   RefSeq;
RL   Submitted (MAR-2019) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|RuleBase:RU003822};
CC       Multi-pass membrane protein {ECO:0000256|RuleBase:RU003822}.
CC   -!- SIMILARITY: Belongs to the inward rectifier-type potassium channel
CC       (TC 1.A.2.1) family. {ECO:0000256|RuleBase:RU003822,
CC       ECO:0000256|SAAS:SAAS00549381}.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   -----------------------------------------------------------------------
DR   RefSeq; XP_006024938.1; XM_006024876.1.
DR   STRING; 38654.XP_006024938.1; -.
DR   GeneID; 102387184; -.
DR   KEGG; asn:102387184; -.
DR   CTD; 3767; -.
DR   KO; K05004; -.
DR   OrthoDB; 956263at2759; -.
DR   Proteomes; UP000189705; Genome assembly.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0015272; F:ATP-activated inward rectifier potassium channel activity; IEA:InterPro.
DR   GO; GO:0034765; P:regulation of ion transmembrane transport; IEA:UniProtKB-KW.
DR   Gene3D; 2.60.40.1400; -; 1.
DR   InterPro; IPR014756; Ig_E-set.
DR   InterPro; IPR041647; IRK_C.
DR   InterPro; IPR016449; K_chnl_inward-rec_Kir.
DR   InterPro; IPR003279; K_chnl_inward-rec_Kir6.2.
DR   InterPro; IPR013518; K_chnl_inward-rec_Kir_cyto.
DR   InterPro; IPR040445; Kir_TM.
DR   PANTHER; PTHR11767; PTHR11767; 1.
DR   PANTHER; PTHR11767:SF44; PTHR11767:SF44; 1.
DR   Pfam; PF01007; IRK; 1.
DR   Pfam; PF17655; IRK_C; 1.
DR   PIRSF; PIRSF005465; GIRK_kir; 1.
DR   PRINTS; PR01332; KIR62CHANNEL.
DR   PRINTS; PR01320; KIRCHANNEL.
DR   SUPFAM; SSF81296; SSF81296; 1.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000189705};
KW   Ion channel {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434609, ECO:0000313|RefSeq:XP_006024938.1};
KW   Ion transport {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434639};
KW   Membrane {ECO:0000256|SAAS:SAAS00434581, ECO:0000256|SAM:Phobius};
KW   Potassium {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434575};
KW   Potassium transport {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434641};
KW   Reference proteome {ECO:0000313|Proteomes:UP000189705};
KW   Transmembrane {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434543, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAAS:SAAS00036756,
KW   ECO:0000256|SAM:Phobius};
KW   Transport {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00036755};
KW   Voltage-gated channel {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00048561}.
FT   TRANSMEM     73     94       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    153    177       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN       37    182       IRK. {ECO:0000259|Pfam:PF01007}.
FT   DOMAIN      190    362       IRK_C. {ECO:0000259|Pfam:PF17655}.
FT   SITE        169    169       Role in the control of polyamine-mediated
FT                                channel gating and in the blocking by
FT                                intracellular magnesium.
FT                                {ECO:0000256|PIRSR:PIRSR005465-1}.
SQ   SEQUENCE   394 AA;  44136 MW;  74200D43392D7E22 CRC64;
     MLSRKGIIPE EYVLTRLAED VPDHARYRAR ERRARFVGKN GACNVAHKNI REQGRFLQDV
     FTTLVDLKWP HTLLIFTMSF LCTWLLFGMG WWLIAFAHGD LDHSTQVERG GDPGGFVPCV
     TSIQSFTSAF LFSIEVQVTI GFGGRMVTEE CPAAILVLIV QNIVGLVINA IMLGCIFMKT
     AQAHRRAETL IFSKHAVIAL REGKLCFMLR VGDLRKSMII SATIRMQVVK KTTSLEGEVV
     PLHQIDIQME NPVGGNSIFL VAPLIVCHVI DQNSPLYDIS PLHLNHQEDL EVIVILEGVV
     ETTGITTQAR TSYLADEILW GQRFVPVVAE EDGRYSVDYS KFGNTVKVPT PSCTARELEE
     NRSIIDTMLQ SPKGTIRKRT VRLKPKFTIS DEPS
//
DBGET integrated database retrieval system