ID A0A1U7SHG0_ALLSI Unreviewed; 289 AA.
AC A0A1U7SHG0;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE RecName: Full=Cytochrome c oxidase subunit 4 {ECO:0000256|RuleBase:RU367145};
GN Name=LOC102371582 {ECO:0000313|RefSeq:XP_006030565.2};
OS Alligator sinensis (Chinese alligator).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Crocodylia; Alligatoridae; Alligatorinae;
OC Alligator.
OX NCBI_TaxID=38654 {ECO:0000313|Proteomes:UP000189705, ECO:0000313|RefSeq:XP_006030565.2};
RN [1] {ECO:0000313|RefSeq:XP_006030565.2}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- FUNCTION: Component of the cytochrome c oxidase, the last enzyme in the
CC mitochondrial electron transport chain which drives oxidative
CC phosphorylation. {ECO:0000256|RuleBase:RU367145}.
CC -!- PATHWAY: Energy metabolism; oxidative phosphorylation.
CC {ECO:0000256|ARBA:ARBA00004673, ECO:0000256|RuleBase:RU367145}.
CC -!- SUBUNIT: Component of the cytochrome c oxidase (complex IV, CIV), a
CC multisubunit enzyme composed of 14 subunits.
CC {ECO:0000256|RuleBase:RU367145}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004167}; Single-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004167}. Mitochondrion
CC inner membrane {ECO:0000256|ARBA:ARBA00004434,
CC ECO:0000256|RuleBase:RU367145}; Single-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004434, ECO:0000256|RuleBase:RU367145}.
CC -!- SIMILARITY: Belongs to the cytochrome c oxidase IV family.
CC {ECO:0000256|ARBA:ARBA00008135, ECO:0000256|RuleBase:RU367145}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR RefSeq; XP_006030565.2; XM_006030503.3.
DR AlphaFoldDB; A0A1U7SHG0; -.
DR STRING; 38654.A0A1U7SHG0; -.
DR GeneID; 102371582; -.
DR KEGG; asn:102371582; -.
DR eggNOG; KOG4075; Eukaryota.
DR InParanoid; A0A1U7SHG0; -.
DR OrthoDB; 5343704at2759; -.
DR UniPathway; UPA00705; -.
DR Proteomes; UP000189705; Unplaced.
DR GO; GO:0005751; C:mitochondrial respiratory chain complex IV; IEA:InterPro.
DR GO; GO:0006123; P:mitochondrial electron transport, cytochrome c to oxygen; IEA:InterPro.
DR CDD; cd00922; Cyt_c_Oxidase_IV; 1.
DR Gene3D; 1.10.442.10; Cytochrome c oxidase subunit IV; 1.
DR InterPro; IPR013288; Cyt_c_oxidase_su4.
DR InterPro; IPR004203; Cyt_c_oxidase_su4_fam.
DR InterPro; IPR036639; Cyt_c_oxidase_su4_sf.
DR PANTHER; PTHR10707:SF11; CYTOCHROME C OXIDASE SUBUNIT 4 ISOFORM 2, MITOCHONDRIAL; 1.
DR PANTHER; PTHR10707; CYTOCHROME C OXIDASE SUBUNIT IV; 1.
DR Pfam; PF02936; COX4; 1.
DR PRINTS; PR01873; CYTCOXIDASE4.
DR SUPFAM; SSF81406; Mitochondrial cytochrome c oxidase subunit IV; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|RuleBase:RU367145};
KW Mitochondrion {ECO:0000256|ARBA:ARBA00023128,
KW ECO:0000256|RuleBase:RU367145};
KW Mitochondrion inner membrane {ECO:0000256|RuleBase:RU367145};
KW Reference proteome {ECO:0000313|Proteomes:UP000189705};
KW Transmembrane {ECO:0000256|RuleBase:RU367145};
KW Transmembrane helix {ECO:0000256|RuleBase:RU367145}.
FT TRANSMEM 223..243
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU367145"
FT REGION 1..21
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 289 AA; 31508 MW; C5280A2C232947D4 CRC64;
MGPRSLWGKH PAGPHPAQLP APCRTGLASA VGRAGSVRPS CPGSRGLGAF LPQPGLAGGG
GNGVLPPSLS CQAGLTTGQA GLTGTGCQEE DGAPISRPLQ GKGCSLQQGM CLPQMLSLPV
LRASFLARRG VLGLAAVRAA HNHGKPVAIQ EDMSVPQYMD KRNHPLPDVP YHRDLSADEK
ALTEKQKGSW KELSNEEKVA LYHIKFCQTY AEMNRPSNEW KTVLGVTFMF LGFTGLILAW
QRYYVMPDKP HTLSDEWKAK QLKRMLDMRM NPVEGLATQW DYDKNEWKK
//
