ID A0A1U7SID2_ALLSI Unreviewed; 219 AA.
AC A0A1U7SID2;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE RecName: Full=Vacuolar protein sorting-associated protein 28 homolog {ECO:0000256|PIRNR:PIRNR017535};
GN Name=VPS28 {ECO:0000313|RefSeq:XP_006038351.1};
OS Alligator sinensis (Chinese alligator).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Crocodylia; Alligatoridae; Alligatorinae;
OC Alligator.
OX NCBI_TaxID=38654 {ECO:0000313|Proteomes:UP000189705, ECO:0000313|RefSeq:XP_006038351.1};
RN [1] {ECO:0000313|RefSeq:XP_006038351.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- FUNCTION: Component of the ESCRT-I complex (endosomal sorting complex
CC required for transport I), a regulator of vesicular trafficking
CC process. {ECO:0000256|PIRNR:PIRNR017535}.
CC -!- SIMILARITY: Belongs to the VPS28 family.
CC {ECO:0000256|PIRNR:PIRNR017535, ECO:0000256|PROSITE-ProRule:PRU00642}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR RefSeq; XP_006038351.1; XM_006038289.3.
DR AlphaFoldDB; A0A1U7SID2; -.
DR STRING; 38654.A0A1U7SID2; -.
DR GeneID; 102375033; -.
DR KEGG; asn:102375033; -.
DR CTD; 51160; -.
DR eggNOG; KOG3284; Eukaryota.
DR InParanoid; A0A1U7SID2; -.
DR OrthoDB; 5486880at2759; -.
DR Proteomes; UP000189705; Unplaced.
DR GO; GO:0000813; C:ESCRT I complex; IEA:UniProtKB-UniRule.
DR GO; GO:0032509; P:endosome transport via multivesicular body sorting pathway; IEA:InterPro.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-UniRule.
DR Gene3D; 1.20.120.1130; -; 1.
DR Gene3D; 1.20.1440.200; -; 1.
DR InterPro; IPR037202; ESCRT_assembly_dom.
DR InterPro; IPR007143; Vps28.
DR InterPro; IPR017899; VPS28_C.
DR InterPro; IPR037206; VPS28_C_sf.
DR InterPro; IPR017898; VPS28_N.
DR InterPro; IPR038358; VPS28_N_sf.
DR PANTHER; PTHR12937; VACUOLAR PROTEIN SORTING 28, ISOFORM 2 VPS28; 1.
DR PANTHER; PTHR12937:SF0; VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 28 HOMOLOG; 1.
DR Pfam; PF03997; VPS28; 1.
DR PIRSF; PIRSF017535; VPS28; 1.
DR SUPFAM; SSF140111; Endosomal sorting complex assembly domain; 1.
DR SUPFAM; SSF140427; VPS28 C-terminal domain-like; 1.
DR PROSITE; PS51310; VPS28_C; 1.
DR PROSITE; PS51313; VPS28_N; 1.
PE 3: Inferred from homology;
KW Endosome {ECO:0000256|ARBA:ARBA00022753, ECO:0000256|PIRNR:PIRNR017535};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927,
KW ECO:0000256|PIRNR:PIRNR017535};
KW Reference proteome {ECO:0000313|Proteomes:UP000189705};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|PIRNR:PIRNR017535}.
FT DOMAIN 12..119
FT /note="VPS28 N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51313"
FT DOMAIN 122..218
FT /note="VPS28 C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51310"
SQ SEQUENCE 219 AA; 25304 MW; F57F4C02D0181A93 CRC64;
MFHGIPAPGM GAPGNKPELY EEVKLYKNAR EREKYDNMAE LFAVVKTMQA LEKAYIKDCV
SPNEYTAACS RLLVQYKAAF KQVQGSEISS IDEFCRKFRL DCPLAMERIK EDRPITIKDT
SSPYVPWLGE PSLFITVMDK LRLEIRAMDE IQPDLRELME TMNRMSHLPP DFEGRQKVNQ
WLQTLSGMSA SDELDDSQVR QMLFDLESAY NAFNRFLHS
//
