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Database: UniProt
Entry: A0A1U7SJJ2_ALLSI
LinkDB: A0A1U7SJJ2_ALLSI
Original site: A0A1U7SJJ2_ALLSI 
ID   A0A1U7SJJ2_ALLSI        Unreviewed;       284 AA.
AC   A0A1U7SJJ2;
DT   10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT   10-MAY-2017, sequence version 1.
DT   08-MAY-2019, entry version 10.
DE   RecName: Full=Deoxyribonuclease {ECO:0000256|PIRNR:PIRNR000988};
GN   Name=DNASE1 {ECO:0000313|RefSeq:XP_006036898.1};
OS   Alligator sinensis (Chinese alligator).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Crocodylia; Alligatoridae; Alligatorinae;
OC   Alligator.
OX   NCBI_TaxID=38654 {ECO:0000313|Proteomes:UP000189705, ECO:0000313|RefSeq:XP_006036898.1};
RN   [1] {ECO:0000313|RefSeq:XP_006036898.1}
RP   IDENTIFICATION.
RG   RefSeq;
RL   Submitted (MAR-2019) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the DNase I family.
CC       {ECO:0000256|PIRNR:PIRNR000988}.
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DR   RefSeq; XP_006036898.1; XM_006036836.1.
DR   STRING; 38654.XP_006036898.1; -.
DR   GeneID; 102381685; -.
DR   KEGG; asn:102381685; -.
DR   CTD; 1773; -.
DR   KO; K11994; -.
DR   OrthoDB; 1282784at2759; -.
DR   Proteomes; UP000189705; Genome assembly.
DR   GO; GO:0004536; F:deoxyribonuclease activity; IEA:InterPro.
DR   GO; GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.
DR   GO; GO:0006308; P:DNA catabolic process; IEA:InterPro.
DR   Gene3D; 3.60.10.10; -; 1.
DR   InterPro; IPR018057; Deoxyribonuclease-1_AS.
DR   InterPro; IPR016202; DNase_I.
DR   InterPro; IPR033125; DNASE_I_2.
DR   InterPro; IPR036691; Endo/exonu/phosph_ase_sf.
DR   InterPro; IPR005135; Endo/exonuclease/phosphatase.
DR   Pfam; PF03372; Exo_endo_phos; 1.
DR   PIRSF; PIRSF000988; DNase_I_euk; 1.
DR   PRINTS; PR00130; DNASEI.
DR   SMART; SM00476; DNaseIc; 1.
DR   SUPFAM; SSF56219; SSF56219; 1.
DR   PROSITE; PS00919; DNASE_I_1; 1.
DR   PROSITE; PS00918; DNASE_I_2; 1.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000189705};
KW   Disulfide bond {ECO:0000256|PIRSR:PIRSR000988-2};
KW   Endonuclease {ECO:0000256|PIRNR:PIRNR000988};
KW   Hydrolase {ECO:0000256|PIRNR:PIRNR000988};
KW   Nuclease {ECO:0000256|PIRNR:PIRNR000988};
KW   Reference proteome {ECO:0000313|Proteomes:UP000189705};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     22       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        23    284       Deoxyribonuclease. {ECO:0000256|SAM:
FT                                SignalP}.
FT                                /FTId=PRO_5010543179.
FT   DOMAIN       48    274       Endo/exonuclease/phosphatase.
FT                                {ECO:0000259|Pfam:PF03372}.
FT   ACT_SITE    100    100       {ECO:0000256|PIRSR:PIRSR000988-1}.
FT   ACT_SITE    156    156       {ECO:0000256|PIRSR:PIRSR000988-1}.
FT   DISULFID    123    126       {ECO:0000256|PIRSR:PIRSR000988-2}.
FT   DISULFID    195    231       Essential for enzymatic activity.
FT                                {ECO:0000256|PIRSR:PIRSR000988-2}.
SQ   SEQUENCE   284 AA;  31988 MW;  CCC6C126D74B5C2C CRC64;
     MGAMKLVLSL LTVAYLLHTA ATLRISAFNI RTCGDTKLSN ETIAGIIVNI LSMYDLIVVQ
     EVRDSDLSAV KKLMNKLNRM SPHLYSYVVS LPLGRTSYKE QYLFIYRTGM MSVVDSYYYE
     DGCESCMNDT FSREPFIVKF SSPHTEVKEF VLVPLHASPN EAAAEIDALY DVYLDVISKW
     ATDNILFLGD FNAGCSYVSP EDWASIRLRT NRAFQWLIPD SADTTVSHTV CAYDRIVASG
     SEMKSCLIPE TAHVNNFQRA FNLQYKDALA VSDHFPVEVT LRSF
//
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