ID A0A1U7TNR7_CARSF Unreviewed; 473 AA.
AC A0A1U7TNR7;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE SubName: Full=Serine incorporator 3 {ECO:0000313|RefSeq:XP_008058013.1};
GN Name=SERINC3 {ECO:0000313|RefSeq:XP_008058013.1};
OS Carlito syrichta (Philippine tarsier) (Tarsius syrichta).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Tarsiiformes; Tarsiidae;
OC Carlito.
OX NCBI_TaxID=1868482 {ECO:0000313|Proteomes:UP000189704, ECO:0000313|RefSeq:XP_008058013.1};
RN [1] {ECO:0000313|RefSeq:XP_008058013.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the TDE1 family.
CC {ECO:0000256|ARBA:ARBA00006665}.
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DR RefSeq; XP_008058013.1; XM_008059822.1.
DR AlphaFoldDB; A0A1U7TNR7; -.
DR STRING; 1868482.ENSTSYP00000002123; -.
DR Ensembl; ENSTSYT00000002297; ENSTSYP00000002123; ENSTSYG00000002293.
DR GeneID; 103262195; -.
DR KEGG; csyr:103262195; -.
DR CTD; 10955; -.
DR OMA; GNPRVWY; -.
DR OrthoDB; 53161at2759; -.
DR Proteomes; UP000189704; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0051607; P:defense response to virus; IEA:Ensembl.
DR GO; GO:0009597; P:detection of virus; IEA:Ensembl.
DR GO; GO:0045087; P:innate immune response; IEA:Ensembl.
DR InterPro; IPR005016; TDE1/TMS.
DR PANTHER; PTHR10383; SERINE INCORPORATOR; 1.
DR PANTHER; PTHR10383:SF51; SERINE INCORPORATOR 3; 1.
DR Pfam; PF03348; Serinc; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000189704};
KW Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..20
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 21..473
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5010519859"
FT TRANSMEM 36..57
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 97..117
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 132..151
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 158..180
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 200..227
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 239..257
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 406..427
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 447..467
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 473 AA; 52763 MW; B02B5C19B42E0CE3 CRC64;
MGAVLGVFSL ASWVPCLCSG ASCLLCSCCP NCKNSMLTRL IYAFILLLGT IVSWIMLQKE
IEPQLKKIPG FCEEGFKIKV ADIMADKDCD VLVGYKAVYR INFALAIFFF VFSLLMIKVK
TSKDPRAAVH NGFWFFKIAA LVGIMVGSFY IPGSYFTTAW FVVGMIGAFI FILIQLILLV
DSAHSWNESW VNRMEEGNPR LWYAALLSFT SLFYILSIIS VGLLYTYYTK SHGCTENKFF
ISINLIFCVV VSMISIHPKI QEHQPHSGLL QSSVITLYTI YLTWSAMSNE PDRSCNPSLL
SFLTNIAAPT LAPGNSTAVA PTSPPPSKSG PSLNSENLVG LFVFVVCLLY SSIRNSSNSQ
VNKLTLSGSD SVILRDTSTN GANDEEEGQP RRAVDNEKEG VQYSYFFFHF MLSLASLYIM
MTLTSWYSPD AKFQNMTSKW PAVWVKISSS WVCLLLYVWT LVAPLVLTNR DFS
//
