ID A0A1U7USN1_NICSY Unreviewed; 378 AA.
AC A0A1U7USN1;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=Protein SRG1-like isoform X1 {ECO:0000313|RefSeq:XP_009757223.1};
GN Name=LOC104210113 {ECO:0000313|RefSeq:XP_009757223.1};
OS Nicotiana sylvestris (Wood tobacco) (South American tobacco).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae;
OC Nicotiana.
OX NCBI_TaxID=4096 {ECO:0000313|Proteomes:UP000189701, ECO:0000313|RefSeq:XP_009757223.1};
RN [1] {ECO:0000313|Proteomes:UP000189701}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23773524; DOI=10.1186/gb-2013-14-6-r60;
RA Sierro N., Battey J.N., Ouadi S., Bovet L., Goepfert S., Bakaher N.,
RA Peitsch M.C., Ivanov N.V.;
RT "Reference genomes and transcriptomes of Nicotiana sylvestris and Nicotiana
RT tomentosiformis.";
RL Genome Biol. 14:R60.1-R60.17(2013).
RN [2] {ECO:0000313|RefSeq:XP_009757223.1}
RP IDENTIFICATION.
RC TISSUE=Leaf {ECO:0000313|RefSeq:XP_009757223.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the iron/ascorbate-dependent oxidoreductase
CC family. {ECO:0000256|ARBA:ARBA00008056, ECO:0000256|RuleBase:RU003682}.
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DR RefSeq; XP_009757223.1; XM_009758921.1.
DR AlphaFoldDB; A0A1U7USN1; -.
DR SMR; A0A1U7USN1; -.
DR GeneID; 104210113; -.
DR KEGG; nsy:104210113; -.
DR eggNOG; KOG0143; Eukaryota.
DR OrthoDB; 1057251at2759; -.
DR Proteomes; UP000189701; Unplaced.
DR GO; GO:0016706; F:2-oxoglutarate-dependent dioxygenase activity; IEA:UniProt.
DR GO; GO:0031418; F:L-ascorbic acid binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0009805; P:coumarin biosynthetic process; IEA:UniProt.
DR GO; GO:0002238; P:response to molecule of fungal origin; IEA:UniProt.
DR InterPro; IPR026992; DIOX_N.
DR InterPro; IPR044861; IPNS-like_FE2OG_OXY.
DR InterPro; IPR027443; IPNS-like_sf.
DR InterPro; IPR005123; Oxoglu/Fe-dep_dioxygenase.
DR PANTHER; PTHR47991:SF4; FE2OG DIOXYGENASE DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR47991; OXOGLUTARATE/IRON-DEPENDENT DIOXYGENASE; 1.
DR Pfam; PF03171; 2OG-FeII_Oxy; 1.
DR Pfam; PF14226; DIOX_N; 1.
DR SUPFAM; SSF51197; Clavaminate synthase-like; 1.
DR PROSITE; PS51471; FE2OG_OXY; 1.
PE 3: Inferred from homology;
KW Iron {ECO:0000256|ARBA:ARBA00023004, ECO:0000256|RuleBase:RU003682};
KW Metal-binding {ECO:0000256|RuleBase:RU003682};
KW Oxidoreductase {ECO:0000256|RuleBase:RU003682};
KW Reference proteome {ECO:0000313|Proteomes:UP000189701};
KW Vitamin C {ECO:0000256|ARBA:ARBA00022896}.
FT DOMAIN 222..322
FT /note="Fe2OG dioxygenase"
FT /evidence="ECO:0000259|PROSITE:PS51471"
SQ SEQUENCE 378 AA; 42835 MW; 923AD821531EF18B CRC64;
MFWNGKGRGQ LTEAMDESPP EVVNFGKSLL VPSVQELANE HLTNIPARYV RPEQESPAVS
DGTVGPTVPV IDLKKLVSGD SMDSELQKLH SACQHWGFLQ VVNHGVTPSI LENFKREVIE
LFSLTMEEKK KLWQQEGNHE GFGQLFVVSE EQKLDWSDMF YITTLPPHIR QMELFQNLPS
NLRDIMEAYC NEIKSLGMII LCQLAKALRM DEKEMRELFS DGVQSIRMNY YPPCPEPDRT
IGFSPHSDAD ALTILFQLNE TEGLQVRKDG IWVPIKPLPN ALIVNIGDIM EIVSNGVYRS
IEHRAVVNSN KERLSVATFY SSNLDSELGP AHSLIGPSSP AIFRRVPVEK YFKDFFARKL
DGKSYIDFMK EEARDGES
//
