ID A0A1U7UVX3_NICSY Unreviewed; 807 AA.
AC A0A1U7UVX3;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE RecName: Full=Beta-galactosidase {ECO:0000256|ARBA:ARBA00012756, ECO:0000256|RuleBase:RU000675};
DE EC=3.2.1.23 {ECO:0000256|ARBA:ARBA00012756, ECO:0000256|RuleBase:RU000675};
GN Name=LOC104212581 {ECO:0000313|RefSeq:XP_009760187.1};
OS Nicotiana sylvestris (Wood tobacco) (South American tobacco).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae;
OC Nicotiana.
OX NCBI_TaxID=4096 {ECO:0000313|Proteomes:UP000189701, ECO:0000313|RefSeq:XP_009760187.1};
RN [1] {ECO:0000313|Proteomes:UP000189701}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23773524; DOI=10.1186/gb-2013-14-6-r60;
RA Sierro N., Battey J.N., Ouadi S., Bovet L., Goepfert S., Bakaher N.,
RA Peitsch M.C., Ivanov N.V.;
RT "Reference genomes and transcriptomes of Nicotiana sylvestris and Nicotiana
RT tomentosiformis.";
RL Genome Biol. 14:R60.1-R60.17(2013).
RN [2] {ECO:0000313|RefSeq:XP_009760187.1}
RP IDENTIFICATION.
RC TISSUE=Leaf {ECO:0000313|RefSeq:XP_009760187.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Hydrolysis of terminal non-reducing beta-D-galactose residues
CC in beta-D-galactosides.; EC=3.2.1.23;
CC Evidence={ECO:0000256|ARBA:ARBA00001412,
CC ECO:0000256|RuleBase:RU000675};
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 35 family.
CC {ECO:0000256|ARBA:ARBA00009809, ECO:0000256|RuleBase:RU003679}.
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DR RefSeq; XP_009760187.1; XM_009761885.1.
DR AlphaFoldDB; A0A1U7UVX3; -.
DR GeneID; 104212581; -.
DR OrthoDB; 5489808at2759; -.
DR Proteomes; UP000189701; Unplaced.
DR GO; GO:0004565; F:beta-galactosidase activity; IEA:UniProtKB-EC.
DR GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR CDD; cd22842; Gal_Rha_Lectin_BGal; 1.
DR Gene3D; 2.60.120.740; -; 1.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 2.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR InterPro; IPR048913; BetaGal_gal-bd.
DR InterPro; IPR008979; Galactose-bd-like_sf.
DR InterPro; IPR031330; Gly_Hdrlase_35_cat.
DR InterPro; IPR019801; Glyco_hydro_35_CS.
DR InterPro; IPR001944; Glycoside_Hdrlase_35.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR InterPro; IPR000922; Lectin_gal-bd_dom.
DR InterPro; IPR043159; Lectin_gal-bd_sf.
DR PANTHER; PTHR23421:SF63; BETA-GALACTOSIDASE 12; 1.
DR PANTHER; PTHR23421; BETA-GALACTOSIDASE RELATED; 1.
DR Pfam; PF21467; BetaGal_gal-bd; 2.
DR Pfam; PF02140; Gal_Lectin; 1.
DR Pfam; PF01301; Glyco_hydro_35; 1.
DR PRINTS; PR00742; GLHYDRLASE35.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF49785; Galactose-binding domain-like; 2.
DR PROSITE; PS01182; GLYCOSYL_HYDROL_F35; 1.
DR PROSITE; PS50228; SUEL_LECTIN; 1.
PE 3: Inferred from homology;
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295, ECO:0000256|RuleBase:RU000675};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU000675};
KW Reference proteome {ECO:0000313|Proteomes:UP000189701};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..26
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 27..807
FT /note="Beta-galactosidase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5010542173"
FT DOMAIN 721..807
FT /note="SUEL-type lectin"
FT /evidence="ECO:0000259|PROSITE:PS50228"
SQ SEQUENCE 807 AA; 89791 MW; C0B543038462287D CRC64;
MQSVNVLLLL SLFFSFFSLF CSSVRATVSY DDRAIIINGK RRILISGSIH YPRSTPEMWP
GLIQKAKDGG LDIIETYVFW NGHEPSPGKF KFEGRYDLVK FIKLVQQAGL YVNLRIGPYI
CGEWNFGGFP VWLKYVPGME FRADNHPFKL AMQGFVEKIV NMMKSENLFE PQGGPIILAQ
IENEYGPIEW EVGSPGKAYT KWAAEMAVGL EIGVPWIMCK QEDAPDHVID TCNGFYCEDF
RPNKPYKPKM WTEVWTAWYT KFGGPVPRRP AEDLAFSVAR FIQNNGSFFN YYMYHGGTNF
GRTTSALFIA TSYDYDAPLD EYGLLNEPKY GHLRDLHKAI KLSEPALISS YPTVNWLGKN
QEAHVFRSKS GDCAAFLSNY DTKYSISSQC SQMMMAPVVG SLSWQSYSEE TPSAEESDTL
SANGLLEQIN ITRDSSDYLW YMTDVNVGPD EGFLKNGKDP FLTVMSAGHA MHVFINGQLS
GTVYGGLDNP KLTYSGNVKL RAGINKISLL SVAVGLPNVG LHFESWNTGV LGPVTLSGLN
DGTRDLTIQR WSYKVGLKGE SLSFHTSSGG SSVEWVEGSL LAQRQPLTWY KATFDAPEGN
DPVALDMVSM GKGQIWVNGE GVGRQWPGYI AKGHCGECNY AGEYTEKKCQ TNCGQPSQRW
YHVPRSWLKP SGNLLVVFEE WGGVPTRISL VRRATARVCA DIVDGQPTLK NWRTVSSGKS
NNMHPKAHLC CPDGKKISKI QFASYGVPQG TCGNFREGTC HAHKSYDAFE KNCIGRQSCS
LNVVPEVFGG DPCPNTSKKL SVEAICR
//
